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CareDx Launches Two Expanded Indications for AlloSure Testing Services

DAIC

The Transplant Company recently announced that AlloSureis now commercially available for pediatric heart transplant patients of all ages and patients who have received a simultaneous pancreas-kidney (SPK) transplant. 1 "The availability of AlloSure dd-cfDNA for all pediatric heart transplant patients is a major development.

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Revolutionary Genomic Study Sheds Light on Immune Microenvironment in Transplanted Pediatric Hearts

DAIC

Pictured Left to Right: Members and students of the McGill Gene Editing Laboratory at The Texas Heart Institute in Houston, Texas: Fansen Meng, PhD, Xiao Li, PhD, James Martin, MD, PhD, Rich Li, PhD (back), Maggie Lim (undergraduate student at Rice University front), Yuka Morikawa, PhD, Ann Bromley.

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A retrospective study of infantile-onset Takayasu arteritis: experience from a tertiary referral center in China

Frontiers in Cardiovascular Medicine

A comprehensive evaluation of clinical, laboratory, radiographic features, disease activity, treatment and outcomes was carried out. The mean Pediatric Vasculitis Activity Score (PVAS), Takayasu Clinical Activity Score (ITAS-2010) and ITAS-A scores were 2.8/63, All patients had aberrant laboratory parameters. 36) months.

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Interplay between mitochondrial dysfunction and lysosomal storage: challenges in genetic metabolic muscle diseases with a focus on infantile onset Pompe disease

Frontiers in Cardiovascular Medicine

Methods We performed a retrospective analysis to examine the clinical manifestations, genetic traits, and the relationship between PD and mitochondrial function in a pediatric patient. Laboratory tests and echocardiography confirmed heart failure and hypertrophic cardiomyopathy.

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Associations Between End-Tidal Carbon Dioxide During Pediatric Cardiopulmonary Resuscitation, CPR Quality, and Survival

Circulation

Background:Supported by laboratory and clinical investigations of adult cardiopulmonary arrest, resuscitation guidelines recommend monitoring end-tidal carbon dioxide (ETCO2) as an indicator of CPR quality but note that "specific values to guide therapy have not been established in children."Methods:This Circulation, Ahead of Print.

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Abstract WP225: Changes in Hemoglobin Levels During Vascular Events in Moyamoya Arteriopathy

Stroke Journal

Laboratory data for each vascular event (stroke or TIA) were collected. The most recent laboratory data preceding events were also collected (baseline). Perioperative events (those occurring ≤7 days after revascularization) were excluded.

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Abstract 4146022: Serology supportive of recent coxsackievirus B infection is correlated with Multisystem Inflammatory Syndrome in Children (MIS-C)

Circulation

To explore an association with MIS-C we investigated the sero-epidemiology of CV in admitted pediatric patients.Method:A retrospective case control study was performed by chart review of children (age ≤ 21) admitted to a tertiary care hospital with CV serological testing from January 2017 to August 2023. of cases respectively.