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Blood pressure trial intervention shows mixed outcomes in chronic kidney disease patients

Medical Xpress - Cardiology

Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidney disease (CKD).

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Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing

Journal of Clinical Investigation - Cardiology

of cases, a qualifying potentially disease-causing rare variant in an established gene was found. This information may inform genetic testing and counseling in the clinic.

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Research shows sotagliflozin is the first medication of its kind to significantly reduce both heart attacks and strokes

Medical Xpress - Cardiology

Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart attack and stroke among these patients, according to results from an international clinical trial led by a Mount Sinai researcher.

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Pentoxifylline ameliorates subclinical atherosclerosis progression in patients with type 2 diabetes and chronic kidney disease: a randomized pilot trial

Cardiovascular Diabetology

Diabetic kidney disease (DKD) is associated with a higher risk of cardiovascular disease (CVD). Pentoxifylline (PTF), a nonselective phosphodiesterase inhibitor with anti-inflammatory, antiproliferative, and a.

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Chronic kidney disease linked to key cardiovascular risk precursor

Medical Xpress - Cardiology

Overactivation of the sympathetic nervous system is a hallmark sign of chronic kidney disease (CKD) that increases the risk of cardiovascular disease. This may contribute to sympathetic nervous system overactivation and related problems, according to researchers from Vitam—Research Center Health Durable in Canada.

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Adults younger than 40 with ideal heart health had lower heart disease, stroke, and kidney disease risk

American Heart News - Heart News

Research Highlights: A study of nearly 4 million young adults under age 40 in South Korea found that those who had ideal cardiovascular health were nearly two-thirds less likely to develop heart disease, stroke and/or kidney disease during a 12-year.

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Bioinformatics analysis of the expression of potential common genes and immune-related genes between atrial fibrillation and chronic kidney disease

Frontiers in Cardiovascular Medicine

Research objectiveThis study is based on bioinformatics analysis to explore the co-expressed differentially expressed genes (DEGs) between atrial fibrillation (AF) and chronic kidney disease (CKD), identify the biomarkers for the occurrence and development of the two diseases, investigate the potential connections between AF and CKD, and explore the (..)