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SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidney disease.

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EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidney disease.

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Advance in the Treatment of Acute Heart Failure Identified

DAIC

The drug, dapagliflozin, was initially approved for the treatment of Type 2 diabetes, but it since has been shown to reduce the risk of hospitalization for heart failure and death in patients with serious health problems that include heart and chronic kidney disease and heightened cardiovascular risk.

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Multispecialty multidisciplinary input into comorbidities along with treatment optimisation in heart failure reduces hospitalisation and clinic attendance

Open Heart

Outcome measures were (1) all-cause hospitalisations, (2) outpatient clinic attendances and (3) cost. post-MDT; p<0.001), initiation of renin–angiotensin aldosterone system inhibitors in HF with reduced ejection fraction (HFrEF) with advanced chronic kidney disease (9% pre vs 71% post-MDT; p<0.001). ±4 months.

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Predictors of worse outcome after postponing non-emergency cardiac interventions during the COVID-19 pandemic

Open Heart

to 5.12; p=0.049), chronic kidney disease (HR 1.89; 95% CI 1.03 to 3.49; p=0.041) as well as severe valvular heart disease (HR 3.08; 95% CI 1.68 Results The combined end point of death and emergency cardiovascular hospitalisation occurred in 70 (36.3%) of 193 patients with a postponed cardiovascular intervention.

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Abstract 4145609: The Cardiac Conundrum of Cannabis: A Case of Junctional Bradycardia Triggered by Cannabis Use

Circulation

Patient did not report any symptoms and was hemodynamically stable. He was euvolemic on physical exam.

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Abstract WP252: MARS: Migraine and Retinal Stroke - A Population-Based Cohort Study of 39 Million Patients

Stroke Journal

vs. 6.9%, SD 0.1), chronic kidney disease (1.9% This finding sets the stage for future work leveraging both outpatient and pharmacy-based claims to further explore this finding. Patients with migraine were younger (40.2±15.2 standardized difference (SD) 0.38), more likely to be female (81.4% vs. 5.1%, SD 0.12).

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