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Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidneydisease (CKD).
BackgroundInhibition of prostaglandin synthesis by nonsteroidal anti‐inflammatory drugs is associated with cardiovascular mortality and kidneydisease. Longitudinal associations with cardiovascular mortality and kidneyoutcomes (eGFR <60 or <45 mL/min per 1.73
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Panelists discuss the new health measures relevant to chronic kidneydisease (CKD) management and their significance in improving patient care and outcomes.
(MedPage Today) -- A multi-pronged electronic health record-based population health management intervention failed to move the needle for slowing chronic kidneydisease (CKD) progression, a cluster randomized trial showed. Over a median follow.
Among participants with type 2 diabetes and cardiovascular disease, chronic kidneydisease, or both, oral semaglutide (14 mg) was associated with a lower risk of cardiovascular events than placebo after 4 years of follow-up.
Panelists discuss how early detection of chronic kidneydisease (CKD) in stages 2 and 3 can improve patient outcomes across various specialties, including nephrology, cardiology, and primary care.
Acute coronary syndrome (ACS) events in people receiving long-term haemodialysis (HD) are common, present atypically and are associated with poor outcomes. 57 These are some of the reasons that the combination of cardiac and renal disease strike fear into even the most seasoned clinicians.
Kenneth Mahaffey, MD, discusses FLOW trial data showing semaglutide improves cardiovascular outcomes in patients with type 2 diabetes, regardless of CKD severity.
BackgroundThis realworld evidence study compared risks of cardiovascular events in hospital settings among patients with chronic kidneydisease (CKD) with and without hyperkalemia.Methods and ResultsAdults with CKD stages 3b/4 with and without hyperkalemia were identified from Optum's deidentified Market Clarity Data (January 2016August 2022).
End-stage kidneydisease (ESKD) patients are prone to bloodstream infections which may result in a higher risk of cardiac implantable electronic device (CIED) infections.
The goal of the phase 3b SOUL trial was to assess the cardiovascular efficacy of oral semaglutide, a GLP-1 receptor agonist, and to determine the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease (ASCVD), chronic kidneydisease (CKD), or both.
Alexandra Louise Møller, MS, PhD, discusses the results of a PROVALID analysis examining the predictive value of endotrophin levels for predicting CKD events.
BACKGROUND:Intensive blood pressure (BP) control in youth with chronic kidneydisease (CKD) slows progression, delaying the need for kidney replacement therapy (KRT). Hypertension, Ahead of Print. Most youth with CKD have hypertension and BP control is difficult to achieve outside of controlled experimental settings.
Patients with chronic kidneydisease (CKD) on renal replacement therapy (RRT) are at high risk for cardiovascular implantable electronic device (CIED) infections. Although device extraction is standard management, it is often avoided in these patients due to high procedural risks.
(MedPage Today) -- Use of cystatin C and SGLT2 inhibitors were highlighted in the KidneyDisease: Improving Global Outcomes (KDIGO) organization's updated clinical practice guideline. In a synopsis of the recently published guideline -- serving.
Results Baseline characteristics revealed significant differences between NUA and HUA groups, with the latter exhibiting a higher prevalence of males, chronic kidneydisease (CKD) and elevated levels of various biomarkers. Our findings suggest that monitoring and managing SUA could be crucial in improving patient with HF outcomes.
Despite improved glycemic treatment, the impact of glycation on pathological consequences may persist and contribute to adverse clinical outcomes in diabetes. In the present study we.
Meta-analysis on the main outcomes of angiotensin receptorneprilysin inhibitor (ARNI) in heart failure (HF) patients with end-stage kidneydisease (ESKD) on dialysis. However, the evidence on the benefits of ARNI in HF patients with end-stage kidneydisease (ESKD) undergoing dialysis is limited.
Background Advanced chronic kidneydisease (ACKD) is common in patients undergoing percutaneous coronary intervention (PCI) and is associated with adverse outcomes. These patients are often excluded from revascularization studies. The goal of this study was to evaluate the impact of ACKD in patients undergoing PCI.
a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidneydisease (CKD) and other diseases, hasannounced that the U.S. The primary outcome measure is absolute change in the frequency of apnea-hypopnea episodes. tim.hodson Wed, 01/08/2025 - 14:11 Jan.
Chronic kidneydisease was linked to increased mortality, higher costs, and the need for mechanical ventilation among hospitalized patients with sickle cell disease.
2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetic kidneydisease. Clinicians and health care systems must be encouraged to make use of these treatments.”
Publication date: Available online 22 October 2024 Source: The American Journal of Cardiology Author(s): Nathan W. Kong, Joseph M. Kim, Anna K. Krawisz, Patrick Heindel, Archana Tale, Yang Song, Jeffrey L. Weinstein, Mohamad A. Hussain, Eric A.
Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidneydisease, or heart failure, as well as among adults with few cardiovascular risk factors. Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025.
BACKGROUND:Hypertension frequently accompanies chronic kidneydisease (CKD) as etiology and sequela. Hypertension, Volume 80, Issue 12 , Page 2533-2543, December 1, 2023. We defined CKD as a sustained estimated glomerular filtration rate value <60 mL/min per 1.73 m2or a urine albumin-to-creatinine ratio ≥30 mg/g.
Main outcome was SCA identified byInternational Classification of Diseases, Tenth Revision (ICD10).Participants The influence of proteinuria on SCA was stronger in advanced chronic kidneydisease (stage 3 and stage 45).ConclusionsProteinuria Urine protein was measured using the spot urine dipstick method.
The goal of the EMPA-KIDNEY trial was to assess the safety and efficacy of empagliflozin in improving cardiac and renal outcomes among patients with chronic kidneydisease (CKD).
Anemia of chronic disease : A type of anemia commonly seen in patients with long-term health conditions such as kidneydisease or heart disease. Identifying and addressing preoperative anemia before surgery is an important strategy for reducing risks and ensuring better outcomes after heart bypass surgery.
This meta-analysis uses data from patients with type 2 diabetes from 6 outcomes trials to investigate the association of sodium-glucose cotransporter 2 inhibitors with cardiovascular- and kidneydisease–related outcomes.
Key findings presented at the conference included disparities in access to kidney transplantation and waitlisting based on race and neighborhood characteristics, racial and ethnic differences in incident chronic kidneydisease (CKD), and the use of motivational strategies to improve dialysis nonadherence among African American patients.
Cox proportional survival analysis was used to assess outcomes where cardioprotective GLD (any of Sodium Glucose Lowering Transport 2 receptor inhibitors [SGLT2i] and Glucagon Like Peptide Receptor Agonists [GLP-1 RA]) served as a reference. vs. 10.5%) and chronic kidneydisease (3.7% vs. 6.8%), myocardial infarction (7.7%
Panelists discuss the current barriers to urine albumin-creatinine ratio (uACR) testing, strategies to address these barriers, the guideline goals for reducing uACR, and the importance of a multimodal approach, as well as how increased awareness of chronic kidneydisease (CKD) testing can improve patient outcomes and engage health care providers in (..)
The primary outcome was a composite of inhospital adverse events. Associations between multimorbidity patterns and outcomes were evaluated using multivariableadjusted logistic regression models. years]) admitted to the China Chest Pain Center Database between 2016 and 2021. Among 9570 patients, 50% (n=4789) had multimorbidity.
Indeed, numerous studies are currently investigating the impact of such approaches on clinical outcomes and healthcare utilisation. Accordingly, the management of AF has shifted towards a holistic and integrated approach, targeting comorbidities and risk factors, itself associated with improved outcomes. 2 Before the. 2 Before the.
Understanding and addressing the dysregulated immune system is a promising approach to modifying cardiorenal outcomes in people with CKD. Understanding and addressing the dysregulated immune system is a promising approach to modifying cardiorenal outcomes in people with CKD.
This study evaluates the outcomes in patients admitted for HF with and without hyperkalemia.Methods:We used the Nationwide Readmissions Database (NRD) from 2016-2019, extracting adult patients with a primary diagnosis of HF who were admitted between January and November of each year. vs. 2.5%, p < 0.001). 2], p<0.001).Conclusion:Hyperkalemia
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