This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidneydisease (CKD).
Ten presentations will feature new data from the pivotal Phase III FINEARTS-HF cardiovascular (CV) outcomes trial, which investigated KERENDIA for treatingt adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF). Additional ACC.25
BackgroundInhibition of prostaglandin synthesis by nonsteroidal anti‐inflammatory drugs is associated with cardiovascular mortality and kidneydisease. Longitudinal associations with cardiovascular mortality and kidneyoutcomes (eGFR <60 or <45 mL/min per 1.73
(MedPage Today) -- A multi-pronged electronic health record-based population health management intervention failed to move the needle for slowing chronic kidneydisease (CKD) progression, a cluster randomized trial showed. Over a median follow.
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
2 Most are balancing multiple comorbidities, such as obesity, diabetes, hypertension and chronic kidneydisease (CKD). In fact, a 2024 report on heart failure trends and outcomes published in the Journal of Cardiac Failure showed that in patients with heart failure with preserved ejection fraction, 5-year mortality was 75.7%.
Panelists discuss the new health measures relevant to chronic kidneydisease (CKD) management and their significance in improving patient care and outcomes.
Chronic kidneydisease affects 14% of the U.S. population1 and is associated with an extraordinarily high risk of poor outcomes, including progression to end-stage kidneydisease, cardiovascular events, and death.2
Among participants with type 2 diabetes and cardiovascular disease, chronic kidneydisease, or both, oral semaglutide (14 mg) was associated with a lower risk of cardiovascular events than placebo after 4 years of follow-up.
(MedPage Today) -- Use of cystatin C and SGLT2 inhibitors were highlighted in the KidneyDisease: Improving Global Outcomes (KDIGO) organization's updated clinical practice guideline. In a synopsis of the recently published guideline -- serving.
Panelists discuss how early detection of chronic kidneydisease (CKD) in stages 2 and 3 can improve patient outcomes across various specialties, including nephrology, cardiology, and primary care.
Acute coronary syndrome (ACS) events in people receiving long-term haemodialysis (HD) are common, present atypically and are associated with poor outcomes. 57 These are some of the reasons that the combination of cardiac and renal disease strike fear into even the most seasoned clinicians.
Kenneth Mahaffey, MD, discusses FLOW trial data showing semaglutide improves cardiovascular outcomes in patients with type 2 diabetes, regardless of CKD severity.
The goal of the phase 3b SOUL trial was to assess the cardiovascular efficacy of oral semaglutide, a GLP-1 receptor agonist, and to determine the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease (ASCVD), chronic kidneydisease (CKD), or both.
BackgroundThis realworld evidence study compared risks of cardiovascular events in hospital settings among patients with chronic kidneydisease (CKD) with and without hyperkalemia.Methods and ResultsAdults with CKD stages 3b/4 with and without hyperkalemia were identified from Optum's deidentified Market Clarity Data (January 2016August 2022).
End-stage kidneydisease (ESKD) patients are prone to bloodstream infections which may result in a higher risk of cardiac implantable electronic device (CIED) infections.
Alexandra Louise Møller, MS, PhD, discusses the results of a PROVALID analysis examining the predictive value of endotrophin levels for predicting CKD events.
BACKGROUND:Intensive blood pressure (BP) control in youth with chronic kidneydisease (CKD) slows progression, delaying the need for kidney replacement therapy (KRT). Hypertension, Ahead of Print. Most youth with CKD have hypertension and BP control is difficult to achieve outside of controlled experimental settings.
Patients with chronic kidneydisease (CKD) on renal replacement therapy (RRT) are at high risk for cardiovascular implantable electronic device (CIED) infections. Although device extraction is standard management, it is often avoided in these patients due to high procedural risks.
Efficacy and safety of finerenone in patients with chronic kidneydisease and type 2 diabetes by diuretic use: a FIDELITY analysis. c CV composite outcome component(s). d Composite of time to kidney failure, sustained 57% decrease in eGFR from baseline over 4weeks, or kidney-related death. thiazide diuretics).
Results Baseline characteristics revealed significant differences between NUA and HUA groups, with the latter exhibiting a higher prevalence of males, chronic kidneydisease (CKD) and elevated levels of various biomarkers. Our findings suggest that monitoring and managing SUA could be crucial in improving patient with HF outcomes.
Background Chronic KidneyDisease (CKD) stands as a formidable health challenge, recognized not only for its growing prevalence but also for its association with elevated mortality rates. Emerging evidence suggests that CKD is inherently linked to inflammatory processes, marking it as an inflammatory disorder.
Despite improved glycemic treatment, the impact of glycation on pathological consequences may persist and contribute to adverse clinical outcomes in diabetes. In the present study we.
Meta-analysis on the main outcomes of angiotensin receptorneprilysin inhibitor (ARNI) in heart failure (HF) patients with end-stage kidneydisease (ESKD) on dialysis. However, the evidence on the benefits of ARNI in HF patients with end-stage kidneydisease (ESKD) undergoing dialysis is limited.
Background Advanced chronic kidneydisease (ACKD) is common in patients undergoing percutaneous coronary intervention (PCI) and is associated with adverse outcomes. These patients are often excluded from revascularization studies. The goal of this study was to evaluate the impact of ACKD in patients undergoing PCI.
As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidneydisease. Researchers tracked outcomes for a median of just under 18 months.
a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidneydisease (CKD) and other diseases, hasannounced that the U.S. The primary outcome measure is absolute change in the frequency of apnea-hypopnea episodes. tim.hodson Wed, 01/08/2025 - 14:11 Jan.
in the composite primary outcome of kidney failure, serious eGFR decline, or death compared to placebo. Participants receiving semaglutide had an overall hazard ratio of 0.76
Chronic kidneydisease was linked to increased mortality, higher costs, and the need for mechanical ventilation among hospitalized patients with sickle cell disease.
Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidneydisease, or heart failure, as well as among adults with few cardiovascular risk factors. Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025.
Main outcome was SCA identified byInternational Classification of Diseases, Tenth Revision (ICD10).Participants The influence of proteinuria on SCA was stronger in advanced chronic kidneydisease (stage 3 and stage 45).ConclusionsProteinuria Urine protein was measured using the spot urine dipstick method.
The goal of the EMPA-KIDNEY trial was to assess the safety and efficacy of empagliflozin in improving cardiac and renal outcomes among patients with chronic kidneydisease (CKD).
BackgroundBoth nighttime systolic blood pressure and pulse rate are associated with adverse outcomes in patients with chronic kidneydisease (CKD). Cox regression was used to explore the association between nighttime DP and adverse outcomes.
milla1cf Fri, 06/28/2024 - 19:07 June 28, 2024 — AstraZeneca has set out a new ambition for Healthy Heart Africa , its flagship health equity initiative, to target a broader range of non-communicable diseases (NCDs), including chronic kidneydisease (CKD) as well as hypertension and cardiovascular disease.
2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetic kidneydisease. Clinicians and health care systems must be encouraged to make use of these treatments.”
Publication date: Available online 22 October 2024 Source: The American Journal of Cardiology Author(s): Nathan W. Kong, Joseph M. Kim, Anna K. Krawisz, Patrick Heindel, Archana Tale, Yang Song, Jeffrey L. Weinstein, Mohamad A. Hussain, Eric A.
BACKGROUND:Hypertension frequently accompanies chronic kidneydisease (CKD) as etiology and sequela. Hypertension, Volume 80, Issue 12 , Page 2533-2543, December 1, 2023. We defined CKD as a sustained estimated glomerular filtration rate value <60 mL/min per 1.73 m2or a urine albumin-to-creatinine ratio ≥30 mg/g.
Mineralocorticoid receptor antagonist (MRA) use in severe chronic kidneydisease and heart failure with reduced ejection fraction (HFrEF). CI, confidence interval; eGFR, estimated glomerular filtration rate; HR, hazard ratio. m 2 , respectively. An eGFR ≥60 ml/min/1.73 m
BACKGROUND:Patients with end-stage kidneydisease undergoing dialysis are at significant risk of stroke. Whether dialysis modality is associated with cerebrovascular disease is unclear. The primary outcome was incident acute ischemic stroke. Stroke, Volume 54, Issue 12 , Page 3054-3063, December 1, 2023.
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content