Stroke Journal

FEBRUARY 1, 2024

The primary efficacy end point was achievement of modified Thrombolysis in Cerebral Ischemia (mTICI) reperfusion scores of ≥2b on first pass. MCA tortuosity was calculated using Inflection Count Metric(ICM) by two blinded readers to angiographical/clinical outcomes. Good functional outcomes was defined as mRS0-2 on 90-day followup.

Atrial Fibrillation 40

Atrial Fibrillation Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

The bootstrap resampling method was considered internal validation of the model.Results:Age (< 70 years), premorbid status (mRS 0), National Institutes of Health Stroke Scale (NIHSS) (< 20), and recanalization status after the MT (modified Thrombolysis in Cerebral Ischemia [mTICU] ≥2b) were related to 90-day mRS 0-3.

Stroke 40

Stroke Strokes Circulation Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Successful recanalization was defined as modified Thrombolysis in Cerebral Ischemia Score≥ 2b. The primary outcome was a 90-day modified Rankin Scale (mRS) of 0-3. Secondary outcomes were symptomatic intracranial hemorrhage and intracranial hemorrhage within 24 hours and mortality at 90 days.

Outcomes 40

Outcomes Stroke Strokes Hemorrhage 40

Stroke: Vascular and Interventional Neurology

AUGUST 16, 2023

In CRAO, the time between initial insult to presentation is significant because, analogous to ischemic stroke, the duration of ischemia is inversely related to viable retinal tissue. Intravenous thrombolysis is a compelling therapeutic approach, with current limited data suggesting early intervention (4.5

Article 40

Article Thrombolysis Risk Factors Ischemia 40

Dr. Smith's ECG Blog

AUGUST 3, 2017

Computer read: "Non-specific ST abnormality, consider anterior subendocardial ischemia" There are very poor R-waves in V1-V4 suggesting old anterior MI. Firstly, subendocardial ischemia does not localize on 12-Lead ECG. But the real question at hand is: Are these precordial ST-depressions a result of subendocardial ischemia?

Chest Pain 52

Chest Pain Myocardial Infarction STEMI Ischemia 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Rescue treatment with stenting, balloon angioplasty, and/or intraarterial thrombolysis or antiplatelets are often required to treat the underlying stenosis. IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1

Stents 40

Stents Stent Circulation Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Often caused by sudden interruption of blood flow to the spinal cord due to embolic phenomena, intrinsic factors such as connective tissue disease, and due to intra/post‐operative hypotension leading to ischemia or infarction.

Embolism 40

Embolism Thrombolysis Cancer Ischemia 40

EMS 12-Lead

AUGUST 14, 2022

A second 12 Lead ECG was recorded: This is a testament to the dynamic nature of coronary thrombosis and thrombolysis. Accurate identification is absolutely necessary as this pattern can be easily misinterpreted for something less nefarious: for example, generic “subendocardial ischemia.” But the lesion is still active!

STEMI 52

STEMI Sudden Cardiac Death Thrombosis Thrombolysis 52

Ken Grauer, MD

APRIL 9, 2023

As discussed in ECG Blog #108 — AIVR generally occurs in one of the following C linical S ettings : i ) As a rhythm during cardiac arrest; ii ) In the monitoring phase of acute MI ( especially with inferior MI ) ; or , iii ) As a reperfusion arrhythmia ( ie, following thrombolysis, acute angioplasty, or spontaneous reperfusion ).

Blog 78

Blog Chest Pain Arrhythmia Cardiac Arrest 78

Dr. Smith's ECG Blog

OCTOBER 3, 2018

Blinded physicians adjudicated angiogram reports for coronary lesions and thrombolysis in myocardial infarction (TIMI) flow score. There is no way the ST-T wave should change from lead V4-to-V5 as we see here given the similar all negative QRS appearance in these 2 leads, unless there is acute ischemia.

Chest Pain 52

Chest Pain Myocardial Infarction STEMI Ischemia 52

Dr. Smith's ECG Blog

MARCH 11, 2016

More likely, the patient had crescendo angina, with REVERSIBLE ischemia for 48 hours that only became potentially irreversible (STEMI) at that point in time. During the 48 hours of angina, such reversible ischemia often leads to myocardial stunning with akinesis of the myocardial wall that puts it at risk for thrombus.

Myocardial Infarction 52

Myocardial Infarction Pericarditis Angina STEMI 52

Dr. Smith's ECG Blog

DECEMBER 14, 2022

Is this Acute Ischemia? Reperfusion of OMI indicates at least partial thrombolysis of occluding thrombus, but still unstable plaque rupture, which can reocclude at any moment. No formal echo was done, and EF was normal on ventriculogram during cath, with no obvious wall motion abnormalities. More on LVH. LVH with anterior ST Elevation.

Chest Pain 52

Chest Pain STEMI Blog Stenosis 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Outcomes included complications, NIHSS at discharge, final modified TICI (thrombolysis in cerebral ischemia) scores including the first‐pass effect (FPE, defined as mTICI 2c/3 after first pass), modified‐FPE (defined as, mTICI 2b‐3 after first pass), symptomatic intracranial hemorrhage (SITS‐MOST definition), and death at discharge.

Thrombolysis 40

Thrombolysis Ischemia Hemorrhage Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Secondary outcomes included complete recanalization (modified Thrombolysis in Cerebral Ischemia [mTICI] ≥ 2C) and 90-day mortality rate. Introduction:The efficacy of mechanical thrombectomy (MT) for tandem vertebrobasilar occlusion (tVBO) is not well established in patients with basilar artery occlusion (BAO).Objective:To

Outcomes 40

Outcomes Thrombolysis Ischemia Stroke 40

DAIC

FEBRUARY 7, 2024

Man’s winning presentation, Abstract 43, “Race-Ethnic Specific Trends in Stroke Thrombolysis Care Metrics in Relation to U.S. The Stroke Care in Emergency Medicine Award encourages investigators to undertake or continue research in the emergent phase of acute stroke treatment and submit an abstract to the International Stroke Conference.

Stroke 105

Stroke Strokes Research Health Disparities 105

Dr. S. Venkatesan MD

NOVEMBER 8, 2024

08/11, 12:07] Dr S Venkatesan: Is the therapeutic time window for primary PCI and thrombolysis same ? [08/11, Thrombolysis has a broader time window, but efficacy decreases significantly after 6 hours. [ 08/11, 12:13] Dr S Venkatesan: Time windows are related to time taken for myocardial cell death because of ischemia.

Thrombolysis 40

Thrombolysis Ischemia Hospital Outcomes 40