Ischemia, Strokes and Thrombolysis - Cardiovascular Update

Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study

Stroke Journal

JANUARY 4, 2024

Stroke, Ahead of Print. BACKGROUND:The effectiveness of intravenous thrombolysis (IVT) before endovascular treatment (EVT) has been investigated in randomized trials and meta-analyses. These studies mainly concerned anterior circulation occlusions. All patients with a posterior circulation occlusion were included.

Thrombolysis

Thrombolysis Circulation Hemorrhage Outcomes

Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke

Stroke Journal

NOVEMBER 9, 2023

Stroke, Volume 54, Issue 12 , Page 3190-3201, December 1, 2023. STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke.

Stroke

Stroke Strokes Academic Thrombolysis

Abstract WP192: Impact of Second Line Thrombectomy Technique Following Failed First Pass Thrombectomy for Anterior Circulation Stroke: To Switch or Not to Switch?

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP192-AWP192, February 1, 2024. Introduction:Despite comparable outcomes for different frontline techniques in mechanical thrombectomy (MT) for acute ischemic stroke (AIS), there are sparse data regarding if and when to switch techniques if the first pass is unsuccessful.

Stroke

Stroke Strokes Circulation Thrombolysis

Abstract 225: Rescue Stenting for Posterior Circulation Strokes

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 1 ICAD‐related strokes are at high risk for re‐occlusion following MT.

Stent

Stent Stents Circulation Stroke

Abstract WP205: Development and Validation of a Prediction Model for Outcome in Mechanical Thrombectomy for Large-Vessel Occlusion Anterior Circulation Stroke With Low ASPECTS

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP205-AWP205, February 1, 2024. The aim of this study is to develop and validate a stroke prediction tool for outcome in MT for AIS patients with low ASPECTS using data from an ongoing international multicenter registry, the Stroke Thrombectomy and Aneurysm Registry (STAR).Methods:236

Stroke

Stroke Strokes Circulation Outcomes

Abstract TP193: Impact of Number of Passes on Outcomes of Mechanical Thrombectomy in Stroke Patients With Low ASPECTS

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP193-ATP193, February 1, 2024. Successful recanalization was defined as modified Thrombolysis in Cerebral Ischemia Score≥ 2b. The primary outcome was a 90-day modified Rankin Scale (mRS) of 0-3.

Outcomes

Outcomes Stroke Strokes Hemorrhage

Abstract TP188: Diving MCA and First-Pass Reperfusion: A Subgroup Analysis of the Arise II Study

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP188-ATP188, February 1, 2024. Here, we investigate the association of middle cerebral artery(MCA) tortuosity on radiographic and functional outcome.Methods:The Analysis of Revascularization in Ischemic Stroke with EmboTrap II was utilized to identify patients with anterior circulation stroke.

Atrial Fibrillation

Atrial Fibrillation Thrombolysis Ischemia Stroke

Abstract TP195: Impact of Intracranial Atherosclerotic Disease on Thrombectomy Outcomes in Acute Cerebral Infarction With Large Vessel Occlusion

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP195-ATP195, February 1, 2024. This study compares post-thrombectomy outcomes in both groups, matched by initial NIHSS scores.Method:From October 2017 to March 2023, we studied LVO cases undergoing thrombectomy for acute ischemic stroke.

Outcomes

Outcomes Embolism Atrial Fibrillation Thrombolysis

Rivaroxaban Plus Aspirin Versus Aspirin Alone After Endovascular Revascularization for Symptomatic PAD: Insights From VOYAGER PAD

Circulation

OCTOBER 18, 2023

The primary efficacy outcome was a composite of acute limb ischemia, major amputation of a vascular pathogenesis, myocardial infarction, ischemic stroke, or cardiovascular death. The principal safety end point was Thrombolysis in Myocardial Infarction major bleeding. 1.03]) or surgical LER (HR, 0.81 [95% CI, 0.67–0.98];Pinteraction=0.43).

Peripheral Arterial Disease

Peripheral Arterial Disease Myocardial Infarction Thrombolysis Ischemia

Central Retinal Artery Occlusion: A Review of Pathophysiological Features and Management

Stroke: Vascular and Interventional Neurology

AUGUST 16, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that results in painless vision loss attributable to retinal infarction. Intravenous thrombolysis is a compelling therapeutic approach, with current limited data suggesting early intervention (4.5

Article

Article Thrombolysis Risk Factors Ischemia

Abstract 163: Total Spinal Cord Infarction, An Underrecognized Postoperative Complication

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. 1% of all strokes, with complete or posterior spinal cord involvement detailed in the case below being even rarer. IntroductionSpinal cord infarctions (SCI) are scarce entities, constituting only 0.3‐1%

Embolism

Embolism Thrombolysis Cancer Ischemia

American Stroke Association to Honor 11 Leading Scientists at International Stroke Conference ISC 2024

DAIC

FEBRUARY 7, 2024

During the American Stroke Association’s International Stroke Conference 2024, ISC24, eleven scientists leading the way in stroke research will be recognized for their exceptional professional achievements. Sacco Outstanding Stroke Research Mentor Award, which honors Ralph L. 7-9 in Phoenix, AZ. 7-9 in Phoenix, AZ.

Stroke

Stroke Strokes Research Health Disparities

Abstract 221: EARLY EXPERIENCE OF EMBOGUARD BALLOON GUIDE CATHETER IN LARGE VESSEL OCCLUSION THROMBECTOMY

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionEndovascular thrombectomy (EVT) is the standard of care in acute ischemic stroke secondary to large vessel occlusion in selective patients within the first 24 hours. Non‐dominant M2, M3, and A2 occlusions were excluded.

Thrombolysis

Thrombolysis Ischemia Hemorrhage Stroke

Abstract TMP88: Impact of Tandem Vertebrobasilar Occlusion on Outcome of Mechanical Thrombectomy for Basilar Artery Occlusion

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP88-ATMP88, February 1, 2024. Secondary outcomes included complete recanalization (modified Thrombolysis in Cerebral Ischemia [mTICI] ≥ 2C) and 90-day mortality rate. The primary outcome was the 90-day modified Rankin Scale (mRS) score 0-2.

Outcomes

Outcomes Thrombolysis Ischemia Stroke

Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study

Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke

Abstract WP192: Impact of Second Line Thrombectomy Technique Following Failed First Pass Thrombectomy for Anterior Circulation Stroke: To Switch or Not to Switch?

Abstract 225: Rescue Stenting for Posterior Circulation Strokes

Abstract WP205: Development and Validation of a Prediction Model for Outcome in Mechanical Thrombectomy for Large-Vessel Occlusion Anterior Circulation Stroke With Low ASPECTS

Abstract TP193: Impact of Number of Passes on Outcomes of Mechanical Thrombectomy in Stroke Patients With Low ASPECTS

Abstract TP188: Diving MCA and First-Pass Reperfusion: A Subgroup Analysis of the Arise II Study

Abstract TP195: Impact of Intracranial Atherosclerotic Disease on Thrombectomy Outcomes in Acute Cerebral Infarction With Large Vessel Occlusion

Rivaroxaban Plus Aspirin Versus Aspirin Alone After Endovascular Revascularization for Symptomatic PAD: Insights From VOYAGER PAD

Central Retinal Artery Occlusion: A Review of Pathophysiological Features and Management

Abstract 163: Total Spinal Cord Infarction, An Underrecognized Postoperative Complication

American Stroke Association to Honor 11 Leading Scientists at International Stroke Conference ISC 2024

Abstract 221: EARLY EXPERIENCE OF EMBOGUARD BALLOON GUIDE CATHETER IN LARGE VESSEL OCCLUSION THROMBECTOMY

Abstract TMP88: Impact of Tandem Vertebrobasilar Occlusion on Outcome of Mechanical Thrombectomy for Basilar Artery Occlusion

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