Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP356-ATP356, February 1, 2025. Background and Rationale:Acute hyperglycemia caused by cerebral ischemia occurs when there is a lack of oxygen, resulting in anaerobic glycolysis. We demonstrated that ischemia accelerates aging-like processes in the brain.

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Ischemia Stroke Strokes 40

ECG Cases

SEPTEMBER 12, 2023

Jesse MacLaren guides us through 10 cases of patients who present with generalized weakness or acute neurologic symptoms and discusses how to look for ECG signs of dysrhythmias, electrolyte emergencies, acute coronary occlusion, and demand ischemia in patients with generalized weakness and in patients with neurologic symptoms, to consider predisposing (..)

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Dysrhythmia Atrial Fibrillation Embolism Blog 131

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A113-A113, February 1, 2025. Background:Early detection and intervention of cerebral ischemia is critical to improving patient outcomes. This method has the potential to identify ischemic changes and facilitate expeditious intervention.

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Ischemia Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP365-ATP365, February 1, 2025. Introduction:Polymorphonuclear leukocytes (PMNs) are among the first leukocytes recruited to the infarct following reperfusion in ischemic stroke. Infarct size was determined via triphenyl tetrazolium chloride staining.

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Ischemia Stroke Strokes Circulation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP368-ATP368, February 1, 2025. Ischemic stroke affects more than 600,000 Americans annually. Brain edema in the acute phase of ischemia-reperfusion primarily associates with early-stage neurovascular damage and plays a major role in poor outcomes of stroke.

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Stroke Strokes Ischemia Outcomes 40

Stroke Journal

MARCH 6, 2024

Stroke, Ahead of Print. BACKGROUND:Ischemic stroke is often accompanied by oxidative stress and inflammatory response, both of which work synergistically to exacerbate the disruption of the blood-brain barrier and ischemic brain injury. The ALK inhibitor alectinib was administered following the stroke.

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Stroke Strokes Ischemia Cancer 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. Acute ischemic stroke is a leading cause for neurological disability worldwide, and treatment strategies are rapidly evolving. Patient selection for recanalization therapy and postintervention management relies heavily on diagnostic imaging.

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Stroke Strokes Ischemia Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A45-A45, February 1, 2024. Introduction:Telestroke enables timely and remote evaluation of patients with acute stroke syndromes. However, stroke mimics represent more than 30% of this population. To predict stroke mimic, TS had the highest AUC (68.3)

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Stroke Journal

MARCH 31, 2025

Stroke, Ahead of Print. Preventing or reversing no-reflow has the potential to augment the clinical benefit of reperfusion treatment in ischemic stroke. BACKGROUND:Tissue-level hypoperfusion (no-reflow) persists in 30% of patients with seemingly successful upstream angiographic recanalization at thrombectomy.

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Stroke Strokes Outcomes Ischemia 74

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP233-ATP233, February 1, 2025. While nearly all stroke patients undergo neuroimaging during acute triage, many patients do not initially present to EVT-capable centers, and interhospital transfer for the EVT procedure can result in significant time delays. hours from initial neuroimaging.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP20-AWMP20, February 1, 2025. Background:Neuronal circuitry remodeling which compromises excitatory and inhibitory neurons is critical to improve neurological outcome after stroke.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP371-AWP371, February 1, 2025. The significance of cranial bone marrow-derived leukocytes following ischemic stroke in the setting of ischemia/reperfusion remains uncertain.

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Ischemia Circulation Stroke Strokes 40

Stroke Journal

NOVEMBER 9, 2023

Stroke, Volume 54, Issue 12 , Page 3190-3201, December 1, 2023. STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP26-ADP26, February 1, 2025. The function of these novel RNAs within the post-stroke brain remains virtually unexplored. Results:We discovered 46 eSINE-RNAs upregulated in the cortex following MCAO, 33 of which were unique to stroke and not detected in the sham group.

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Stroke Strokes Outcomes Ablation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP372-ATP372, February 1, 2025. Introduction:Ischemic stroke is highly heterogeneous, with patient-to-patient differences in infarct location, severity, and degree of reperfusion, among other factors.

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Physiology Stroke Strokes Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP357-ATP357, February 1, 2025. Background:Despite the effectiveness of immediate treatment, such as thrombolytic therapy, after a stroke, many patients are unable to benefit due to time restrictions. In cases of acute ischemia, training improved complications and reduced glial activation.

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Ischemia Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP119-ATP119, February 1, 2024. Introduction:“Stroke code” activation is a uniform process to summon healthcare stakeholders to orchestrate the rapid sequential steps for urgent management in patients with possible stroke.

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Circulation Stroke Strokes Ischemia 40

HeartRhythm

APRIL 30, 2024

Strokes and silent ischemia remain a serious complication of atrial fibrillation catheter ablation (AFCA). This is mainly due to extensive ablation lesions in the left atrium that create large areas of endothelial injury that produces prothrombotic states during and after AFCA.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP317-ATP317, February 1, 2024. Background and rationale:Smooth muscle cell-specific cGK1 knock-out mice (SMKO) due to impaired blood vessel motility is a leading cause of reduced blood flow in ischemic stroke. Not only SMLC but also SMKO were the same.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP115-AWMP115, February 1, 2025. Intro:Resources for studying stroke are limited to clinical trials with sparse access to physiological and biochemical details, and pre-clinical animal studies with limited relation to humans. International Stroke Conference, February 7-9 2024, Phoenix2.

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Stroke Strokes Physiology Ischemia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP303-AWP303, February 1, 2024. Introduction:Chronic hypertension decreases collateral blood flow through leptomeningeal anastomoses (LMAs) during ischemic stroke, which has been linked to worsened stroke outcome. mmHg at 60 min. However, oxygenation did not recover in SHR (5.9±0.23

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Hypertension Stroke Strokes Ischemia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP9-AWP9, February 1, 2024. Introduction:Early neurologic deterioration (END) and poor functional outcomes are more frequent with night than daytime onset of ischemic stroke. female, initial NIHSS 7 (IQR 2-15), LKW to randomization 59 mins (IQR 46-80), and 473 (38%) treated with IV lytics.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP359-AWP359, February 1, 2025. Background:Mechanical thrombectomy has been associated with improved outcomes in patients with acute ischemic stroke. Investigating the post-reperfusion inflammatory milieu could provide valuable insights into the mechanisms that influence stroke outcomes.

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Stroke: Vascular and Interventional Neurology

FEBRUARY 1, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. Patients transported to a more distant Thrombectomy Stroke Center traveled an average of 5.7 Patients transported to a more distant Thrombectomy Stroke Center traveled an average of 5.7 minutes shorter. minutes shorter.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP287-ATP287, February 1, 2024. Introduction:Previous stroke studies in female rodents have demonstrated that the severity of ischemic damage is differentially impacted by the estrous cycle. Keywords: stroke, estrous cycle, CBF, estrogen

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP28-ADP28, February 1, 2025. Background:Microglia-mediated inflammatory response directly affects ischemic stroke outcome. Autophagy is crucial in inflammatory response after cerebral ischemia. Histopathological and behavioral methods were performed to assess ischemic injury in mice.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP87-AWMP87, February 1, 2025. Background:Complete recanalization, defined as modified Treatment in Cerebral Ischemia (mTICI) score of 2c or better, has been shown to be superior to mTICI 2b in terms of patient outcomes following stroke thrombectomy.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP296-AWP296, February 1, 2024. Introduction:Stroke patients with type-2 diabetes exhibit exacerbated cerebrovascular dysfunction and increased neurological deficits compared to non-diabetic stroke patients.

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionPediatric patients presenting with atypical stroke symptoms pose a diagnostic challenge, which often causes delays in management. Around a quarter of pediatric stroke patients will present with new onset seizures.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP29-ADP29, February 1, 2025. Introduction:The potential role of tRNA derived fragment (tRF&tiRNA) in ischemic stroke remains largely unknown. Small RNA sequencing analyses were conducted to explore the differentially expressed tRNA derived fragments.

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. This is secondary to delayed postoperative cerebral ischemia and infarction caused by vasospasm.7 This is secondary to delayed postoperative cerebral ischemia and infarction caused by vasospasm.7 compared to a median age of 55 (44.0‐64.0)

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP131-AWP131, February 1, 2024. The Alberta Stroke Program Early CT score (ASPECTS) is a 10-item score of the territory of the middle cerebral artery (MCA). In an ambispective analysis, patients with ischemic Stroke from a national network of hospitals were included.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP213-AWP213, February 1, 2025. Intracerebral Hemorrhagic (ICH) stroke is the second most common type of stroke and its aftermath is often more severe than ischemia. Neural activity (Electrophysiological) data is collected pre/post stroke and during stimulation.

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Hemorrhage Stroke Strokes Electrophysiology 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 1 ICAD‐related strokes are at high risk for re‐occlusion following MT.

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Stents Stent Circulation Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP399-AWP399, February 1, 2025. Background:The neuroinflammation triggered by acute cerebral ischemia can be mediated through inflammasome such as NLRP3 (NOD-like receptor family, pyrin domain containing 3) and ASC (apoptosis-associated speck-like protein). 17/Icr-Jcl mice in this experiment.

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Ischemia Stenosis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A162-A162, February 1, 2025. Background:Preceding respiratory tract infections (RTIs) caused by bacteria or viruses are associated with worse stroke outcomes, likely due to an exaggerated inflammatory immune response, endothelial dysfunction, platelet activation, and coagulopathy. On day 6 (S.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP402-AWP402, February 1, 2025. Background:Patients with hypertension (HTN) are almost 3 times more likely to have a stroke than non-hypertensive individuals. Middle Cerebral Artery Occlusion was used to induce focal ischemia/reperfusion injury (I/R). fold), IL-6 (3.3-fold),

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