Circulation

OCTOBER 18, 2023

BACKGROUND:Rivaroxaban plus aspirin compared with aspirin alone reduced major cardiac and ischemic limb events after lower extremity revascularization (LER) in the VOYAGER PAD (Vascular Outcomes Study of ASA Along With Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease) trial. at 6 months and 2.0%

Peripheral Arterial Disease 40

Peripheral Arterial Disease Myocardial Infarction Thrombolysis Ischemia 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Despite comparable outcomes for different frontline techniques in mechanical thrombectomy (MT) for acute ischemic stroke (AIS), there are sparse data regarding if and when to switch techniques if the first pass is unsuccessful. 3.86, P = 0.002) and 90-day good clinical outcome (adjusted odds ratio 2.10, 95% CI: 1.15-3.85,

Circulation 40

Circulation Stroke Strokes Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

MCA tortuosity was calculated using Inflection Count Metric(ICM) by two blinded readers to angiographical/clinical outcomes. The primary efficacy end point was achievement of modified Thrombolysis in Cerebral Ischemia (mTICI) reperfusion scores of ≥2b on first pass.

Atrial Fibrillation 40

Atrial Fibrillation Thrombolysis Ischemia Hemorrhage 40

Dr. Smith's ECG Blog

NOVEMBER 4, 2022

This has been termed a “STEMI equivalent” and included in STEMI guidelines, suggesting this patient should receive dual anti-platelets, heparin and immediate cath lab activation–or thrombolysis in centres where cath lab is not available. His response: “subendocardial ischemia. Anything more on history? POCUS will be helpful.”

Ischemia 52

Ischemia STEMI Stenosis Chest Pain 52

Stroke: Vascular and Interventional Neurology

AUGUST 16, 2023

In CRAO, the time between initial insult to presentation is significant because, analogous to ischemic stroke, the duration of ischemia is inversely related to viable retinal tissue. Intravenous thrombolysis is a compelling therapeutic approach, with current limited data suggesting early intervention (4.5

Article 40

Article Thrombolysis Ischemia Risk Factors 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Rescue treatment with stenting, balloon angioplasty, and/or intraarterial thrombolysis or antiplatelets are often required to treat the underlying stenosis. ConclusionPTAS appears to be an effective and safe treatment for ICAD after MT in the posterior circulation both improving likelihood of good outcomes and overall survival.

Stents 40

Stents Stent Circulation Stroke 40

Dr. Smith's ECG Blog

AUGUST 3, 2017

Computer read: "Non-specific ST abnormality, consider anterior subendocardial ischemia" There are very poor R-waves in V1-V4 suggesting old anterior MI. Firstly, subendocardial ischemia does not localize on 12-Lead ECG. But the real question at hand is: Are these precordial ST-depressions a result of subendocardial ischemia?

Chest Pain 52

Chest Pain Myocardial Infarction STEMI Ischemia 52

Dr. Smith's ECG Blog

MARCH 11, 2016

More likely, the patient had crescendo angina, with REVERSIBLE ischemia for 48 hours that only became potentially irreversible (STEMI) at that point in time. During the 48 hours of angina, such reversible ischemia often leads to myocardial stunning with akinesis of the myocardial wall that puts it at risk for thrombus.

Myocardial Infarction 52

Myocardial Infarction Pericarditis Angina STEMI 52

Dr. Smith's ECG Blog

OCTOBER 3, 2018

Details cannot be shared here, but suffice it to say that inability to recognize acute occlusive myocardial infarction in the presence of ventricular paced rhythm contributed to a poor outcome. Blinded physicians adjudicated angiogram reports for coronary lesions and thrombolysis in myocardial infarction (TIMI) flow score.

Chest Pain 52

Chest Pain Myocardial Infarction STEMI Ischemia 52

Stroke Journal

FEBRUARY 1, 2024

Objective:To investigate the treatment outcomes of MT in tVBO.Method:This international, multicenter, retrospective cohort included patients with MT for tVBO and isolated BAO from 2013 to 2023. The primary outcome was the 90-day modified Rankin Scale (mRS) score 0-2. These outcomes were compared between tVBO and isolated BAO groups.

Outcomes 40

Outcomes Thrombolysis Ischemia Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

With the evolving technology and newer generation of catheters and devices, the interest in improving the technical and procedural factors that can help better the recanalization success, clinical outcomes, and efficiency is ever‐growing. Most of the patients had MCA occlusion (68.4% with 50.9% of cases.

Thrombolysis 40

Thrombolysis Ischemia Hemorrhage Stroke 40

Dr. S. Venkatesan MD

NOVEMBER 8, 2024

08/11, 12:07] Dr S Venkatesan: Is the therapeutic time window for primary PCI and thrombolysis same ? [08/11, Thrombolysis has a broader time window, but efficacy decreases significantly after 6 hours. [ 08/11, 12:13] Dr S Venkatesan: Time windows are related to time taken for myocardial cell death because of ischemia.

Thrombolysis 40

Thrombolysis Ischemia Hospital Outcomes 40

Dr. Smith's ECG Blog

MARCH 14, 2025

This case highlights how T-waves are very important in the assessment of ischemia and dynamic changes in acute coronary syndrome. I have often seen colleagues worry about T-wave inversions as a sign of ongoing ischemia. Here is evidence for this: Opiates are associated with worse outcomes in Myocardial Infarction. Am Heart J.

Chest Pain 106

Chest Pain Myocardial Infarction STEMI Ischemia 106