Cardiovascular Diabetology

MAY 19, 2024

There is conflicting evidence whether prediabetes is associated with adverse clinical outcomes in patients with chronic coronary syndrome. We aimed to assess the effect of prediabetes in patients with chronic.

Ischemia 64

Ischemia Outcomes Research 64

American College of Cardiology

JULY 25, 2024

What is the prognostic impact of peri-infarct ischemia on stress cardiovascular magnetic resonance (CMR) imaging?

Ischemia 43

Ischemia Outcomes Article 43

NEJM Journal Watch - Cardiology

JULY 24, 2024

Identifying and treating silent myocardial ischemia was associated with decreased cardiovascular mortality and fewer adverse cardiovascular events at 5 years.

Ischemia 45

Ischemia Outcomes 45

Circulation: Cardiovascular Interventions

DECEMBER 28, 2023

BACKGROUND:Lower-limb amputation rates in patients with chronic limb-threatening ischemia vary across the United States, with marked disparities in amputation rates by gender, race, and income status. Mean age, 76.6 years; women, 38.9%; Black adults, 24.5%; and of low income, 35.2%.

Vascular Care 61

Vascular Care Ischemia Medicare Cardiovascular Interventions 61

Dr. Smith's ECG Blog

JANUARY 2, 2016

There may be ischemia present, but it is not evident on the ECG. In this paper, Dr. Birnbaum writes: "In patients with ACS without LVH, ST depression with negative T waves in the lateral leads is a sign of sub-endocardial ischemia and is an independent predictor of adverse outcome [11 – 13].

Ischemia 52

Ischemia Chest Pain STEMI Myocardial Infarction 52

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 26, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Treatment effects are expressed as an odds ratio for a better health status outcome with an invasive versus conservative treatment strategy using Bayesian hierarchical proportional odds models. Diabetes was present in 28% and multivessel disease in 51%.

Ischemia 40

Ischemia Heart Disease Angina Anatomy 40

DAIC

MARCH 27, 2025

ii to show blood flow through the heart muscle and evaluate the presence, extent and degree of myocardial ischemia or infarction. Around 6 million MPI procedures are undertaken each year in theU.S. Flyrcado is now available in selectU.S.markets.

Coronary Artery Disease 52

Coronary Artery Disease CMS Innovation Ischemia 52

Journal of the American Heart Association

MARCH 27, 2025

Journal of the American Heart Association, Ahead of Print.

Quality of Life 45

Quality of Life Ischemia Outcomes 45

DAIC

FEBRUARY 14, 2024

2 An estimated 10% of patients with PAOD have its most severe form: chronic limb-threatening ischemia (CLTI). Given this dismal outcome, the prognosis of CLTI is worse than most cancers.3,4 Determinants of long-term outcomes and costs in the management of critical limb ischemia: A population-based cohort study.

Heart Attack 111

Heart Attack Heart attacks Peripheral Arterial Disease Ischemia 111

Frontiers in Cardiovascular Medicine

JANUARY 22, 2024

Myocardial ischemia may induce myocardial fibrosis, a condition that progressively leads to ventricular remodeling, heightening the risk of heart failure. The timely detection of myocardial fibrosis is crucial for intervention and improved outcomes. The results demonstrated tracer-specific uptake (SUVmax = 4.6)

Angina 69

Angina Ischemia Myocardial Infarction Electrocardiogram 69

Circulation

NOVEMBER 11, 2024

To elucidate this relationship, we investigated gut microbiota dynamics in response to immunosuppression and cell therapy in a nonhuman primate (NHP) cardiac ischemia/reperfusion (IR) model, with controlled genetic, dietary, and environmental factors.

Ischemia 40

Ischemia Transplant Heart Transplant Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). In this study, our hypothesis was that NETs cause vascular occlusion leading to delayed cerebral ischemia (DCI) and worse outcome after SAH. However, degrading NETs only marginally improved outcomes.

Ischemia 40

Ischemia Hemorrhage Aneurysm Outcomes 40

Stroke Journal

JANUARY 30, 2025

Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). Following SAH, neutrophils cause vascular occlusion via neutrophil extracellular traps (NETs) and NETs have been identified as a therapeutic target to prevent delayed cerebral ischemia in mice (DCI) with SAH.

Aneurysm 40

Aneurysm Biomarkers Ischemia Hemorrhage 40

Journal of the American Heart Association

FEBRUARY 14, 2024

Maternal blood and tissues were collected.

Ischemia 40

Ischemia Blood Pressure Circulation Hypertension 40

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 26, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Ischemia 40

Ischemia Circulation Outcomes 40

DAIC

MARCH 20, 2024

The Freesolve BTK RMS is designed for individuals suffering from chronic limb-threatening ischemia (CLTI). Our next generation RMS represents a leap forward over existing resorbable technology, incorporating technical innovations intended to address physicians' needs and optimize outcomes for patients suffering from CLTI.”

Peripheral Arterial Disease 105

Peripheral Arterial Disease Innovation Technology Coronary Artery Disease 105

Stroke Journal

MARCH 31, 2025

A favorable outcome (90-day modified Rankin Scale score of 02 or return to baseline modified Rankin Scale) was observed in 43.33% (n=13/30) of patients with eTICI 2c3NoReflow, 67.50% (n=81/120) of eTICI 2c3CompleteFlow, 63.03% (n=150/238) of eTICI 2b, and 50.00% (n=34/68) of unsuccessful thrombectomy.

Strokes 74

Strokes Stroke Outcomes Ischemia 74

Circulation

NOVEMBER 11, 2024

Background:The incidence of cardiac arrest (CA) increases with age, leading to poorer neurological outcomes after the return of spontaneous circulation (ROSC) in the elderly.

Ischemia 40

Ischemia Cardiac Arrest Circulation Outcomes 40

Stroke Journal

JANUARY 30, 2025

Background:Early detection and intervention of cerebral ischemia is critical to improving patient outcomes. Stroke, Volume 56, Issue Suppl_1 , Page A113-A113, February 1, 2025. This method has the potential to identify ischemic changes and facilitate expeditious intervention.

Ischemia 40

Ischemia Stroke Strokes Outcomes 40

Dr. Smith's ECG Blog

FEBRUARY 9, 2024

The first ECG was labeled “anterior subendocardial ischemia”, but subendocardial ischemia does not localize. If there were diffuse ischemic STD, with precordial STDmaxV5-6 and reciprocal STE-aVR, this would be non-specific subendocardial ischemia from ACS or supply-demand mismatch.

Chest Pain 114

Chest Pain STEMI Atrial Flutter Ischemia 114

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundLittle is known about treatment variability across US hospitals for patients with chronic limb‐threatening ischemia (CLTI).Methods The primary outcome of interest was variability in CLTI treatment, as characterized by the median odds ratio. Journal of the American Heart Association, Ahead of Print.

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Inpatient Ischemia Hospital Outcomes 40

ECG Guru

JULY 24, 2023

ST depression in the setting of acute transmural ischemia (STEMI) is almost ALWAYS due to reciprocal change. Outcome: The patient went to the cath lab, but we have no further followup. The elevation is higher in Lead III than in Lead II, a reliable sign of RCA occlusion. Reciprocal depression in Leads aVL and I.

Chest Pain 98

Chest Pain STEMI Ischemia Outcomes 98

DAIC

JULY 23, 2024

Brittany Weber, MD, PhD , of Brigham and Women’s Hospital, is the 2024 YIA winner for her abstract, "The Frequency, Prevalence, And Outcomes Of Incidentally Detected Coronary Artery Calcium Using Artificial Intelligence Analysis Among Patients With Immune Mediated Inflammatory Diseases.”

Chest Pain 105

Chest Pain Coronary Artery Disease Plaque Ischemia 105

Dr. Smith's ECG Blog

JUNE 5, 2024

The ECG does not show any definite signs of ischemia. This combination is often extremely effective for maintaining good longterm outcome ( Lanza and Shimokawa — Eur Cardiol 18: e38, 2023 ). The patient presented due to chest pain that was typical in nature, retrosternal and radiating to the left arm and neck.

Chest Pain 122

Chest Pain Blog Cardiac Arrest Cardiomyopathy 122

Heart BMJ

OCTOBER 28, 2024

1 Indeed, if the recently published ORBITA-2 trial demonstrated the benefit of revascularisation in relieving angina symptoms, 2 many other trials aiming to show a benefit on hard outcomes have failed in their purpose. 3 The ISCHEMIA-EXTEND reported the extended follow-up of the recent ISCHEMIA trial.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Angioplasty Angina Ischemia 52

Dr. Smith's ECG Blog

FEBRUARY 14, 2024

When the ischemia is resolved, if there is no infarction, the T-wave can normalize. When I see a case like this, I am skeptical that the ECG is manifesting acute ischemia or reperfused OMI. Outcome: All hs troponin I ﹤ 3 ng/L (undetectable). On occasion, unstable angina can present with reversible T-wave inversion during pain.

Chest Pain 110

Chest Pain Angina Ischemia Outcomes 110

Stroke Journal

JANUARY 30, 2025

Introduction:Oxidative stress plays an important role in both early brain injury and delayed cerebral ischemia after subarachnoid hemorrhage (SAH). In this study, we evaluated the effect of MnP-05 on short-term outcomes of SAH in mice.Methods:We used 12-week-old male C57BL/6J mice. P<0.05, Fig.

Hemorrhage 40

Hemorrhage Outcomes Blood Pressure Ischemia 40

Stroke Journal

FEBRUARY 1, 2024

However, clinical outcomes remain similar. This study compares post-thrombectomy outcomes in both groups, matched by initial NIHSS scores.Method:From October 2017 to March 2023, we studied LVO cases undergoing thrombectomy for acute ischemic stroke. Successful recanalization was defined as Thrombolysis in Cerebral Ischemia score ≥2b.

Outcomes 40

Outcomes Embolism Atrial Fibrillation Thrombolysis 40

Dr. Smith's ECG Blog

AUGUST 6, 2024

In any case, the ECG is diagnostic of severe ischemia and probably OMI. So this could be myocarditis but in my opinion needs an angiogram before making that diagnosis. == Dr. Nossen Comment/Interpretation: Evaluation of ischemia on an ECG can be very challenging. Concordant STE of 1 mm in just one lead or 2a.

Chest Pain 104

Chest Pain Ischemia Pericarditis Tachycardia 104

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

The degree of ischemia-reperfusion injury (IRI), which occurs during the harvest and implantation of the grafts, is an important determinant of graft patency. There was also a non-ischemia-reperfusion control group ( n  = 8). Introduction Coronary artery bypass grafting (CABG) is the most common cardiac surgical procedure.

Coronary Artery Bypass Graft 64

Coronary Artery Bypass Graft Transplant Ischemia Aortic 64

Dr. Smith's ECG Blog

AUGUST 2, 2024

In this patient's case, the RV ischemia manifested as dramatic anterior hyperacute T waves. This degree of STE is a bit atypical for LAD ischemia. the investigators reviewed outcomes in 118 patients presenting with NSTEMI. Remember that the RV is the most anterior chamber. Here is a transverse image of a CT showing this.

STEMI 119

STEMI Ischemia Blog Chest Pain 119

Stroke Journal

FEBRUARY 1, 2024

Introduction:Real-world data showed that less than half of the acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) presenting with low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) (2-5) achieved favorable outcomes at 90 days after mechanical thrombectomy (MT). was related to 90-day mRS 0-3.

Outcomes 40

Outcomes Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

aureus-infected WT,Vwf-/-,Adamts13-/-mice were subjected to transient (30 min) middle cerebral artery ischemia using a filament model. Functional outcomes (modified neurological severity score, rota-rod, corner, novel object recognition, and wire-hanging test) were measured in the same cohort of mice up to 4 weeks. aureusinfected WT).

Outcomes 40

Outcomes Stroke Strokes Thrombosis 40

Dr. Smith's ECG Blog

JUNE 27, 2021

If this STD were due to LVH or to subendocardial ischemia, rather than posterior OMI, it would be maximal in V5 and V6. If I saw this without the STD V2-V4, I would not make anything of it, and even with that precordial STD, I am not convinced that it is a manifestation of ischemia. Alcohol intoxication? V5-V6), even if less than 0.1

Myocardial Infarction 40

Myocardial Infarction Ischemia STEMI Pulmonary 40

Dr. Smith's ECG Blog

NOVEMBER 3, 2023

The baseline ECG is basically normal with no ischemia. You can see in the lead-specific analysis that she "sees" the STD in V5, V5, and II, with STE in aVR as signs of "Not OMI", because subendocardial ischemia pattern is not the same as OMI. In my opinion, I think it looks more like subendocardial ischemia.

Chest Pain 82

Chest Pain Cardiogenic Shock Ischemia Myocardial Infarction 82

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The aim of this study is to provide outcome comparisons between WEB and BAC in a specific cohort of patients with ruptured wide‐necked IAs.MethodsIn this international cohort study, we included consecutive patients treated for ruptured wide‐neck IAs with either WEB or BAC at three neurovascular centers. Of the patients, 60.5%

Aneurysm 40

Aneurysm Outcomes Hemorrhage Stents 40

Stroke Journal

JANUARY 30, 2025

Background:Complete recanalization, defined as modified Treatment in Cerebral Ischemia (mTICI) score of 2c or better, has been shown to be superior to mTICI 2b in terms of patient outcomes following stroke thrombectomy. Stroke, Volume 56, Issue Suppl_1 , Page AWMP87-AWMP87, February 1, 2025.

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Stroke Strokes Outcomes Ischemia 40