ECG Cases

SEPTEMBER 10, 2024

Help Support EM Cases by Giving a Donation here: [link] The post EM Quick Hits 59 Traumatic Coronary Artery Dissection, Proper Use of Insulin, Mesenteric Ischemia, Exercise Associated Hyponatremia, AI for OMI appeared first on Emergency Medicine Cases.

Ischemia 107

Ischemia Exercise SCAD 107

Cardiology Update

JANUARY 14, 2024

As the medical community delves deeper into the intricacies of ANOCA, the study provides a compelling narrative for clinicians and researchers alike, aiming to decipher the complexities of myocardial bridges and their role in exercise-induced ischemia. Original article: Sinha A et al. Circ Cardiovasc Interv.

Exercise 119

Exercise Ischemia Angina Physiology 119

Dr. Smith's ECG Blog

MAY 30, 2024

ischemia) or it can be secondary to abnormal depolarization (e.g Discussion: The ECG in today's case does not have typical ST depression vector of diffuse subendocardial ischemia. The ST vector in subendocardial ischemia (SEI) usually has the largest amount of ST depression in leads II and V5, towards the apex of the heart. (ST

Ischemia 88

Ischemia Coronary Angiogram Pulmonary STEMI 88

DAIC

FEBRUARY 23, 2024

Food and Drug Administration ( FDA )-cleared Cleerly ISCHEMIA software device applied to a non-invasive coronary CT angiogram ( CCTA ) can be billed using the new Category I CPT code 75580. Prior studies have demonstrated the independent and incremental benefit of Cleerly ISCHEMIA applied to CCTA beyond traditional assessment.

Ischemia 105

Ischemia Coronary Artery Disease Physiology Cardiovascular Imaging 105

DAIC

MAY 2, 2024

a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, today announced the primary endpoint results of the open label roll-in cohort of the CardiAMP Cell Therapy in Chronic Myocardial Ischemia Trial. Getty Images milla1cf Thu, 05/02/2024 - 10:12 May 2, 2024 — BioCardia, Inc. ,

Ischemia 95

Ischemia Angina Heart Failure Outcomes 95

Dr. Smith's ECG Blog

SEPTEMBER 18, 2024

This confirms that the pain was ischemia and is now resovled. The cardiology fellow agreed with plan for emergent cath and escorted the patient to the cath lab. Another ECG was recorded after the nitroglycerine and now without pain: All findings are resolved. The i nitial hs troponin I returned 75%.

Ischemia 122

Ischemia Plaque Stenosis Myocardial Infarction 122

Journal of the American Heart Association

FEBRUARY 8, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundIschemic stroke is among the most prevalent diseases, with high death and morbidity. Numerous preclinical studies have reported efficacious interventions in rodent stroke models. However, reperfusion therapies remain the only clinically efficacious intervention to date.

Ischemia 45

Ischemia Stroke Strokes Outcomes 45

Medical Xpress - Cardiology

JANUARY 9, 2024

However, reperfusion itself could induce more severe injury, called myocardial ischemia/reperfusion injury (MI/RI). The most effective treatment for MI in clinic is reperfusion, e.g., interventional or thrombolytic therapy.

Ischemia 75

Ischemia Myocardial Infarction Research 75

Science Daily - Heart Disease

APRIL 10, 2024

Over 200 million people around the world experience peripheral artery disease (PAD) -- a condition caused by the narrowing of the blood vessels from the heart to the lower limbs that leads to pain when walking -- and for roughly 1-in-10 this advances to chronic limb-threatening ischemia (CLTI), an advanced form of PAD.

Quality of Life 70

Quality of Life Ischemia Peripheral Arterial Disease Plaque 70

Cardiovascular Diabetology

MAY 30, 2024

Ischemia and no obstructive coronary artery disease (INOCA) is increasingly recognized and associated with poor outcomes. The triglyceride-glucose (TyG) index is a reliable alternative measure of insulin resis.

Coronary Artery Disease 59

Coronary Artery Disease Ischemia Outcomes Research 59

American College of Cardiology

JANUARY 2, 2024

The goal of the MINT trial was to compare the effect of a liberal vs. restrictive blood transfusion strategy on acute myocardial infarction (MI) in patients with concomitant anemia.

Ischemia 75

Ischemia Myocardial Infarction Article 75

Cardiovascular Diabetology

DECEMBER 1, 2024

However, its role in diabetic hind-limb ischemia was not. Adipsin (complement factor D, CFD), as the first described adipokine, is well-known for its regulatory effects in diabetic cardiovascular complications.

Ischemia 52

Ischemia Diabetes Research 52

NEJM Journal Watch - Cardiology

MARCH 12, 2025

No, according to a randomized trial in the U.K.

Ischemia 79

Ischemia Outcomes 79

DAIC

MARCH 28, 2024

The study describes the validation of Cleerly's artificial intelligence-guided quantitative coronary CT angiography (AI-QCT) ISCHEMIA technology for diagnostic accuracy and prognostic risk stratification. High Diagnostic Accuracy of AI-ISCHEMIA in Comparison to PET, FFR-CT, SPECT, and Invasive FFR: A Pacific Substudy. 2024.01.007.

Ischemia 110

Ischemia Chest Pain Atherosclerosis Coronary Artery Disease 110

Frontiers in Cardiovascular Medicine

MARCH 18, 2025

Finally, we also emphasize the preclinical/clinical translational significance of neutrophil-targeted strategies.

Cardiovascular Disease 52

Cardiovascular Disease Atrial Fibrillation Atherosclerosis Ischemia 52

Frontiers in Cardiovascular Medicine

FEBRUARY 19, 2025

These methods only alleviate symptoms of heart failure and myocardial ischemia and improve patients' quality of life by partially restoring myocardial reperfusion. At present, the main methods to treat ischemic heart disease are drug therapy, intervention and operation.

Myocardial Infarction 52

Myocardial Infarction Quality of Life Heart Transplant Ischemia 52

Dr. Smith's ECG Blog

APRIL 14, 2024

No ischemia. This is a conundrum, because it is clear that the patient is having an acute MI, the ECG is dynamic, but the pain is very mild and there is no ECG evidence of active transmural ischemia. We already know that the ischemia is ongoing, though mild (because of the persistent pain). Q-waves are even more pronounced.

Chest Pain 120

Chest Pain Ischemia Myocardial Infarction Ultrasound 120

Journal of Cardiothoracic Surgery

JANUARY 14, 2025

miRNA, circRNA, and lncRNA play crucial roles in the pathogenesis and progression of myocardial ischemia-reperfusion injury (MI/RI). This study aims to provide valuable insights into miRNA, circRNA, lncRNA, an.

Ischemia 52

Ischemia Research 52

Dr. Smith's ECG Blog

JULY 25, 2024

The ECG shows severe ischemia, possibly posterior OMI. But cardiac arrest is a period of near zero flow in the coronary arteries and causes SEVERE ischemia. It takes time for that ischemia to resolve. The patient was brought to the ED and had this ECG recorded: What do you think? And what do you want to do?

Cardiac Arrest 125

Cardiac Arrest Ischemia Tachycardia Defibrillator 125

EMS 12-Lead

APRIL 9, 2024

Many of the changes seen are reminiscent of LVH with “strain,” and downstream Echo may very well corroborate such a suspicion, but since the ECG isn’t the best tool for definitively establishing the presence of LVH, we must favor a subendocardial ischemia pattern, instead. Type I ischemia. Type II ischemia.

Ischemia 116

Ischemia Stenosis Chest Pain Coronary Artery Disease 116

Cardiovascular Diabetology

JANUARY 17, 2025

Ischemia with nonobstructive coronary arteries (INOCA) has high morbidity, mortality, and poor quality of life. Metabolic syndrome (MetS) is a complex of multiple cardiac metabolic risk factors, significantly.

Ischemia 52

Ischemia Quality of Life Risk Factors Research 52

Stroke Journal

JANUARY 30, 2025

Background and Rationale:Acute hyperglycemia caused by cerebral ischemia occurs when there is a lack of oxygen, resulting in anaerobic glycolysis. Young mice were subjected to time-dependently ischemia induction (0, 1, 2, or 3 h) without reperfusion, and aged mice underwent ischemia for 1 h.

Ischemia 40

Ischemia Stroke Strokes 40

The New England Journal of Medicine

SEPTEMBER 4, 2024

In a 57-year-old man with chest pain, an ECG obtained by EMS showed widespread ST-segment depressions. At the hospital, left main coronary-artery stenosis was seen on angiography (shown in a video).

Ischemia 58

Ischemia Chest Pain Stenosis Hospital 58

Med Page Today

APRIL 29, 2024

(MedPage Today) -- The FDA approved the Esprit BTK everolimus-eluting scaffold system for chronic limb-threatening ischemia (CLTI) below the knee, Abbott announced on Monday. This system represents the first drug-eluting resorbable scaffold with.

Peripheral Arterial Disease 111

Peripheral Arterial Disease Stent Stents Ischemia 111

Cardiovascular Diabetology

MAY 19, 2024

There is conflicting evidence whether prediabetes is associated with adverse clinical outcomes in patients with chronic coronary syndrome. We aimed to assess the effect of prediabetes in patients with chronic.

Ischemia 64

Ischemia Outcomes Research 64

Journal of the American Heart Association

MARCH 17, 2025

BackgroundAcute myocardial ischemia (AMI)triggered ventricular arrhythmias are closely linked to maladaptive sympathetic hyperactivity mediated via the left stellate ganglion (LSG). The retigabine group demonstrated a higher ventricular fibrillation threshold (26.672.61 versus 12.331.76

Ischemia 40

Ischemia Arrhythmia Electrophysiology Blood Pressure 40

Journal of Clinical Investigation - Cardiology

MARCH 3, 2025

The plasticity of Ms offers an opportunity to polarize them toward mediating injury resolution in both native and transplanted kidneys undergoing ischemia and/or rejection. The role of macrophages (Ms) remains incompletely understood in kidney injury and repair.

Kidney Disease 40

Kidney Disease Ischemia Transplant 40

Dr. Smith's ECG Blog

MAY 20, 2024

This EKG is diagnostic of transmural ischemia of the inferior wall. If it is angina, lowering the BP with IV Nitroglycerine may completely alleviate the pain and the (unseen) ECG ischemia. Transmural ischemia (as seen with the OMI findings on ECG) is not very common with demand ischemia, but is possible.

Chest Pain 126

Chest Pain Blood Pressure Ischemia STEMI 126

Med Page Today

JUNE 11, 2024

(MedPage Today) -- An experimental study showed that heat exposure increased myocardial blood flow to put stress on the heart, and some people showed asymptomatic heat-induced myocardial ischemia on imaging. Annals of Internal Medicine) Olfactory.

Ischemia 104

Ischemia Stroke Strokes 104

DAIC

DECEMBER 3, 2024

worsening PAD symptoms leading to revascularization, chronic limb threatening ischemia, and acute limb ischemia events) by 36% compared to placebo. This analysis focused on the incidence of major adverse limb events (MALE) in patients with pre-existing PAD enrolled in the CLEAR Outcomes trial. Bempedoic acid reduced MALE (e.g.

Outcomes 69

Outcomes Peripheral Arterial Disease Ischemia Research 69

DAIC

MARCH 27, 2024

Food and Drug Administration (FDA) for its DynamX BTK System, a novel, adaptive implant for use in the treatment of narrowed or blocked vessels below-the-knee (BTK) in patients with chronic limb-threatening ischemia (CLTI). The natural history of untreated severe or critical limb ischemia. 2013;382(9901):1329-1340. J Vasc Surg.

Peripheral Arterial Disease 111

Peripheral Arterial Disease Ischemia Technology Coronary Artery Disease 111

ECG Cases

JUNE 18, 2024

acute Q waves or loss of R waves, hyperacute T waves, or reciprocal STD/TWI) and if the ECG is nondiagnostic, consider other OMI signs including clinical (refractory ischemia, hemodynamic/electrical instability) and POCUS (new regional wall motion abnormalities).

STEMI 125

STEMI Ischemia 125

Stroke Journal

JANUARY 30, 2025

This study aims to investigate the role of organelle-specific autophagy in rodent brain ischemia models.Methods:Rats and mice were subjected to either sham surgery, 20 min of global ischemia, or 40/120 min of focal brain ischemia, followed by 0.5-, 4-, 24- and 72-h reperfusion, respectively.

Ischemia 40

Ischemia Stroke Strokes 40

ECG Cases

SEPTEMBER 12, 2023

Jesse MacLaren guides us through 10 cases of patients who present with generalized weakness or acute neurologic symptoms and discusses how to look for ECG signs of dysrhythmias, electrolyte emergencies, acute coronary occlusion, and demand ischemia in patients with generalized weakness and in patients with neurologic symptoms, to consider predisposing (..)

Dysrhythmia 128

Dysrhythmia Atrial Fibrillation Embolism Blog 128

Circulation

MARCH 23, 2025

Circulation, Volume 151, Issue 12 , Page 884-886, March 25, 2025.

Ischemia 49

Ischemia Circulation 49

Dr. Smith's ECG Blog

NOVEMBER 22, 2023

Important point: when there is diffuse subendocardial ischemia but no OMI, a wall motion abnormality will not necessarily be present. They agreed ischemia was likely in the setting of demand given DKA and infection. That this is all demand ischemia is unlikely. Lung exam showed diffuse B lines bilaterally. Aslanger's pattern.

Chest Pain 119

Chest Pain Ischemia Echocardiogram Myocardial Infarction 119

Frontiers in Cardiovascular Medicine

DECEMBER 14, 2023

Mitochondrial transplantation provides a novel methodology for rescue of cell viability and cell function following ischemia-reperfusion injury and applications for other pathologies are expanding. In this review we present our methods and acquired data and evidence accumulated to support the use of mitochondrial transplantation.

Transplant 104

Transplant Ischemia 104