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Active plant substance found to reduce pulmonary hypertension

Medical Xpress - Cardiology

Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients.

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Artificial intelligence to improve the diagnosis of pulmonary hypertension: promises and pitfalls

Heart BMJ

Challenges in the diagnosis of pulmonary hypertension Pulmonary hypertension (PH) is a clinical–physiological syndrome thought to affect 1% of the global population. Patients with PH experience symptoms including dyspnoea, fatigue and oedema, often associated with physical and psychosocial disability.

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Upregulation of Angiomotin-like 2 ameliorates experimental pulmonary arterial hypertension by inactivating YAP1 signaling

Journal of Cardiovascular Pharmacology

Abstract: Angiomotin-like 2 (AMOTL2) is related to numerous physiological and pathological conditions by affecting signal transduction. However, whether AMOTL2 is linked to pulmonary arterial hypertension (PAH) has not been addressed. AMOTL2 was downregulated in hypoxia-stimulated pulmonary arterial smooth muscle cells (PASMCs).

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Endothelin System in Hypertension and Chronic Kidney Disease

Hypertension Journal

Hypertension, Ahead of Print. ET (endothelin) is a powerful vasoconstrictor 21-amino acid peptide present in many tissues, which exerts many physiological functions across the body and participates as a mediator in many pathological conditions.

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Clinical risk associated with COVID-19 among 86000 patients with congenital heart disease

Open Heart

The excess risk of COVID-19 hospitalisation and death rose with increasing physiological severity of CHD (presence of pulmonary vascular disease and/or cyanosis), rather than anatomical complexity. Of patients with a positive COVID-19 test, patients with CHD were more likely than controls to be hospitalised (22.4%

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Exercise catheterization in adults post?Fontan with normal and abnormal hemodynamic criteria: insights into normal Fontan physiology

European Journal of Heart Failure

Moreover, the definitions of elevated exercise pulmonary artery (PA) and PA wedge pressure (PAWP) for this population have not been described. The major discrepancy in exercise hemodynamics among Group II compared to controls appears to be the degree of systemic venous hypertension and arterial desaturation. All rights reserved.

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Abstract 4123391: CardioMEMS and Mavacamten: A Synergistic Approach in Managing Hypertrophic Obstructive Cardiomyopathy with HFpEF Phenotype

Circulation

The CardioMEMS PA (pulmonary artery) sensor allows remote pulmonary artery diastolic (PAD) pressure monitoring to adjust diuresis in heart failure with preserved ejection fraction (HFpEF). Circulation, Volume 150, Issue Suppl_1 , Page A4123391-A4123391, November 12, 2024.