Journal of the American Heart Association

FEBRUARY 3, 2025

BackgroundDespite the poor outcomes related to the presence of pulmonary hypertension, it often goes undiagnosed in part because of low suspicion and screening tools not being easily accessible such as echocardiography. Journal of the American Heart Association, Ahead of Print.

Pulmonary 68

Pulmonary Hypertension Echocardiogram Physiology 68

Frontiers in Cardiovascular Medicine

JUNE 26, 2024

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and has become a global public health concern. Although hypertension results from a combination of factors, the specific mechanism is still unclear. We provide a summary of the composition and physiological role of gut microbiota.

Hypertension 52

Hypertension Cerebrovascular Disease Public Health Transplant 52

Medical Xpress - Cardiology

JULY 2, 2024

Exercise testing can serve as a powerful physiologic probe to unmask subclinical cardiovascular abnormalities well before disease onset. For example, blood pressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension.

Hypertension 52

Hypertension Blood Pressure Exercise Physiology 52

Physiologically Speaking

JULY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This irregular sleep pattern misaligns circadian rhythms and disrupts physiology. ICYMI: On Wednesday, I published my video interview with Dr. Andrew Koutnik. “The shorter your sleep, the shorter your life.”

Chronic Disease 64

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 64

DAIC

JANUARY 8, 2025

a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S. We believe suppression of aldosterone production by lorundrostat has the potential to reduce the nocturnal hypertension driving adverse cardiovascular outcomes.

Blood Pressure 52

Blood Pressure Hypertension Kidney Disease BMI 52

Hypertension Journal

DECEMBER 5, 2024

Hypertension, Ahead of Print. Several microRNAs (miRNAs) strongly influence blood pressure and the development of hypertension by modulating vascular, renal, and other physiological mechanisms. In addition, miRNAs may contribute to the genetic regulation of blood pressure.

Hypertension 40

Hypertension Blood Pressure Physiology Research 40

Frontiers in Cardiovascular Medicine

MAY 26, 2024

In addition to the receptor, it also participates in complex pathological and physiological processes, including regulating the RAS system, apelin, KKS system, and immune system. In addition to affecting the respiratory system, viral infections also interact with cardiovascular diseases.

COVID-19 106

COVID-19 Research Cardiovascular Disease Physiology 106

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

The physiology of lipid droplets (LDs) has been most extensively characterized in adipocytes, but LDs also accumulate in endothelial cells lining blood vessels in response to changing levels of triglycerides. Boutagy, Gamez-Mendez, et al.

Cardiovascular Disease 93

Cardiovascular Disease Atherosclerosis Physiology Hypertension 93

Physiologically Speaking

APRIL 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. ICYMI On Wednesday, I published The Ultimate Guide to Sleep and Cardiovascular Health.

Blood Pressure 52

Blood Pressure Physiology Exercise Diet 52

Hypertension Journal

DECEMBER 7, 2023

Hypertension, Ahead of Print. ET (endothelin) is a powerful vasoconstrictor 21-amino acid peptide present in many tissues, which exerts many physiological functions across the body and participates as a mediator in many pathological conditions.

Kidney Disease 45

Kidney Disease Hypertension Pulmonary Atherosclerosis 45

Hypertension Journal

MARCH 31, 2025

Hypertension, Ahead of Print. BACKGROUND:Primary aldosteronism (PA) is a distinct cause of low-renin hypertension (LRH), characterized by inappropriate aldosterone production.

Hypertension 40

Hypertension Physiology Outcomes 40

Hypertension Journal

NOVEMBER 30, 2023

Hypertension, Ahead of Print. Essential hypertension, a multifaceted disorder, is a worldwide health problem. A complex network of genetic, epigenetic, physiological, and environmental components regulates blood pressure (BP), and any dysregulation of this network may result in hypertension.

Hypertension 40

Hypertension Blood Pressure Physiology 40

Hypertension Journal

OCTOBER 23, 2024

Hypertension, Ahead of Print. However, at higher levels of TRPV4 activity, this vasodilatory response is reversed, contributing to the aberrant vascular tone observed in hypertension. Moreover, the data support a new unifying hypothesis for the vascular impairment that accompanies hypertension.

Hypertension 40

Hypertension Physiology 40

DAIC

JANUARY 14, 2025

9, 2025 Gender-based racism through microaggressions may be linked to higher blood pressure postpartum and beyond, according to new research published in Hypertension , a peer-reviewed journal of the American Heart Association. These results emphasize that hypertension management needs to extend beyond prescription medications, she said.

Blood Pressure 52

Blood Pressure Research Hypertension Public Health 52

Hypertension Journal

OCTOBER 21, 2024

Hypertension, Ahead of Print. BACKGROUND:Primary aldosteronism (PA) is a common cause of human hypertension. Somatic mutations inKCNJ5,CACNA1D,ATP1A1, andATP2B3are found in at least 80% of aldosterone-producing adenomas, which cause unilateral PA in humans.

Hypertension 75

Hypertension Physiology 75

Hypertension Journal

NOVEMBER 9, 2023

Hypertension, Ahead of Print. Previous basic and clinical investigations have identified various pathogenic factors and determinants of risk that contribute to hypertension. Nevertheless, the pathogenesis of hypertension has not been fully elucidated.

Hypertension 40

Hypertension Blood Pressure Physiology Risk Factors 40

Cardiometabolic Health Congress

JULY 10, 2024

Bakris , an internationally recognized and influential nephrologist and hypertension expert, who passed away on June 15, 2024, at the age of 72. Bakris’s distinguished career in medicine spanned over four decades, marked by significant contributions to the fields of diabetic kidney disease, hypertension, and nephropathy progression.

Hypertension 52

Hypertension Education Blood Pressure Kidney Disease 52

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.”

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.”

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

JANUARY 10, 2024

Our body’s physiological processes oscillate on a 24-hour cycle known as the circadian rhythm. Day-night oscillations in the release of hormones, body temperature, and a range of other important physiological events orchestrate the complex system that is us. Every process in our body happens rhythmically. Read more

Blood Pressure 131

Blood Pressure Physiology Cardiovascular Disease Obesity 131

Heart BMJ

MARCH 22, 2024

Challenges in the diagnosis of pulmonary hypertension Pulmonary hypertension (PH) is a clinical–physiological syndrome thought to affect 1% of the global population. 1 PH is defined haemodynamically by mean pulmonary artery pressure >20 mm Hg, resulting in right ventricular (RV) overload and often RV failure.

Pulmonary 40

Pulmonary Hypertension Physiology 40

Open Heart

DECEMBER 14, 2023

The excess risk of COVID-19 hospitalisation and death rose with increasing physiological severity of CHD (presence of pulmonary vascular disease and/or cyanosis), rather than anatomical complexity. Of patients with a positive COVID-19 test, patients with CHD were more likely than controls to be hospitalised (22.4% to 1.89); p=7.00e–08).

COVID-19 98

COVID-19 Congenital Heart Disease Congenital Heart Disease 98

Stroke: Vascular and Interventional Neurology

MARCH 6, 2024

We aimed to define the prevalence of systemic hypertension in MMD patients and characterize its evolution after cerebral revascularization.METHODSPatients with MMD treated with extracranial‐intracranial bypass from 2014 to 2018 were retrospectively enrolled. respectively. respectively. 1.09]), body mass index (OR, 1.08 [95% CI, 1.03–1.13]),

Hypertension 40

Hypertension Blood Pressure Pediatrics Kidney Disease 40

Hypertension Journal

SEPTEMBER 6, 2023

Hypertension, Ahead of Print. Excess dietary salt (NaCl) intake is strongly correlated with cardiovascular disease and is a major contributing factor to the pathogenesis of hypertension.

Physiology 40

Physiology Blood Pressure Hypertension Cardiovascular Disease 40

Journal of Cardiovascular Pharmacology

JULY 1, 2024

Abstract: Angiomotin-like 2 (AMOTL2) is related to numerous physiological and pathological conditions by affecting signal transduction. However, whether AMOTL2 is linked to pulmonary arterial hypertension (PAH) has not been addressed. However, whether AMOTL2 is linked to pulmonary arterial hypertension (PAH) has not been addressed.

Pulmonary 40

Pulmonary Hypertension Physiology Article 40

Physiologically Speaking

JANUARY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. What if your calendar was the key to living a longer, healthier life? Health and time have always been two sides of the same coin, but we haven’t had the technology to bridge them until now.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

Dr. S. Venkatesan MD

NOVEMBER 29, 2023

Many times , an Innocuous question poses a real challenge, to our life time understanding of circulatory physiology. In patients with associated supine hypertension, the criteria for orthostatic hypotension allows for a drop of at least 30 mm Hg in SBP or 15 mm Hg in DBP. Can you discuss the answer to the question please ? Reference 1.Wahba

Blood Pressure 52

Blood Pressure Hypertension POTS Physiology 52

MIBHS

JANUARY 31, 2025

The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. Risk Reduction Data from wearables can identify potential risks, such as undiagnosed arrhythmias or hypertension, allowing healthcare teams to address these issues before surgery.

Heart Rhythm 52

Heart Rhythm Technology AFIB Exercise 52

Hypertension Journal

SEPTEMBER 18, 2023

Hypertension, Ahead of Print. Salt (sodium chloride) is an essential nutrient required to maintain physiological functions. However, for most people, daily salt intake far exceeds their physiological need and is habitually greater than recommended upper thresholds.

Blood Pressure 40

Blood Pressure Physiology Hypertension Risk Factors 40

European Journal of Heart Failure

DECEMBER 28, 2023

The major discrepancy in exercise hemodynamics among Group II compared to controls appears to be the degree of systemic venous hypertension and arterial desaturation. There was no difference in exercise arterial O 2 saturation (87% [81;92] vs 89% [85;93], p = 0.29), while exercise PA pressure (27 [23;31] vs 16 [14.5;19.5]

Exercise 40

Exercise Physiology Article Pulmonary 40

Hypertension Journal

SEPTEMBER 28, 2023

Hypertension, Ahead of Print. Race is a social construct, but self-identified Black people are known to have higher prevalence and worse outcomes of hypertension than White people.

Blood Pressure 40

Blood Pressure Physiology Hypertension Risk Factors 40

Hypertension Journal

JULY 14, 2023

Hypertension, Ahead of Print. Dysregulation of β-arrestin signaling has been linked to several cardiovascular diseases including hypertension, atherosclerosis, and heart failure. β-arrestins are a family of intracellular signaling proteins that play a key role in regulating the activity of G protein-coupled receptors.

Cardiovascular Disease 40

Cardiovascular Disease Atherosclerosis Physiology Hypertension 40

Hypertension Journal

DECEMBER 28, 2023

Hypertension, Ahead of Print. family of voltage-gated potassium (K+) channels in the adipose-vascular coupling, translating PVAT signals, particularly oxylipins, to the central physiological function of vasoregulation. BACKGROUND:Small arteries exhibit resting tone, a partially contracted state that maintains arterial blood pressure.

Blood Pressure 51

Blood Pressure Physiology Hypertension 51

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

The kynurenine pathway (KP) serves as the primary route for tryptophan metabolism in most mammalian organisms, with its downstream metabolites actively involved in various physiological and pathological processes.

Cardiovascular Disease 52

Cardiovascular Disease Atherosclerosis Myocardial Infarction Physiology 52

Hypertension Journal

DECEMBER 3, 2024

Hypertension, Ahead of Print. BACKGROUND:Circulating proteins in blood are involved in various physiological processes, but their contributions to blood pressure regulation remain partially understood.

Blood Pressure 40

Blood Pressure Circulation Hypertension Physiology 40

Hypertension Journal

DECEMBER 12, 2023

Hypertension, Ahead of Print. Homeostasis of fluid and electrolytes is a tightly controlled physiological process. Failure of this process is a hallmark of hypertension, chronic kidney disease, heart failure, and other acute and chronic diseases.

Chronic Disease 40

Chronic Disease Kidney Disease Hypertension Physiology 40

Hypertension Journal

DECEMBER 11, 2024

Hypertension, Ahead of Print. Here, we review the generation and regulation of cGMP by PDEs and cyclases, focusing mainly on their role in cardiac physiology and pathophysiology. cGMP plays a central role in cardiovascular regulation in health and disease.

Physiology 40

Physiology Hypertension 40