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Research status of triglyceride glucose-body mass index (TyG-BMI index)

Frontiers in Cardiovascular Medicine

While the triglyceride glucose (TyG) index is widely recognized as a simple and specific surrogate marker for IR, the triglyceride glucose body mass index (TyG-BMI), incorporating obesity metrics, has emerged as a more robust predictor of IR.

BMI
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Molecular crosstalk in perivascular adipose tissue: mechanisms of inflammation, metabolic dysregulation, and therapeutic opportunities in cardiovascular disease

Frontiers in Cardiovascular Medicine

We explore PVAT's molecular interactions in obesity, diabetes, and hypertension, elucidating its contribution to inflammation, oxidative stress, and endothelial dysfunction. Finally, we emphasize multi-omics approaches and propose a roadmap bridging basic and clinical research to advance PVAT-based CVD management.

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What Cardiometabolic Clinicians Can Be Thankful For This Year

Cardiometabolic Health Congress

Diabetes and Obesity Care Advancements New Technologies for Diabetes Management : The recent FDA approvals of various insulin delivery devices, including the Embecta patch pump for Type 2 diabetes , have expanded patient options. These findings strengthen the case for broader utilization of finerenone in heart failure management​.

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Disease classification, diagnostic challenges, and evolving clinical trial design in MASLD

Journal of Clinical Investigation - Cardiology

Metabolic dysfunctionassociated steatotic liver disease (MASLD) diagnosis and management have evolved rapidly alongside the increasing prevalence of obesity and related complications. The renaming of nonalcoholic fatty liver disease (NAFLD) to MASLD reflects its pathophysiology, reduces stigma, and has prompted new research directions.

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Association of plasma homocysteine with cardiovascular disease in American adults: a study based on the national health and nutrition examination survey database

Frontiers in Cardiovascular Medicine

The subgroup analysis revealed that various characteristics such as age, race, education level, obesity, alcohol use, diabetes, and hypertension did not affect this positive correlation (P for interaction ≥0.05). Plasma Hcy levels are considered an independent variable, while CVD is a dependent variable.

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Clinical characteristics, management approaches, and outcomes of patients with heart failure: the Jordan Heart Failure Registry

Frontiers in Cardiovascular Medicine

Obesity was identified in 36.6% Hypertension (80.7%) and a history of atherosclerotic cardiovascular disease (ASCVD) (80.6%) were the most prevalent comorbidities. The mean age of patients was 66 years, with almost half of the patients (45.5%) aged 70 or older. of the cohort.

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A retrospective cross-sectional study of association between triglyceride-glucose index and carotid atherosclerosis

Frontiers in Cardiovascular Medicine

Subgroup analyses revealed stronger associations in younger individuals (<49 years), males, and those without hypertension, dyslipidemia, or hyperglycemia. All statistical analyses were executed using R Statistical Software and the Free Statistics analysis platform.ResultsThe TyG index was positively associated with CA (OR = 1.22, 95% CI: 1.08–1.38,