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FDA Approves Updated Label for Tryvio (aprocitentan)

DAIC

Tryvio is Idorsias dual endothelin receptor antagonist (ERA) indicated for the treatment of systemic hypertension in combination with other antihypertensives to lower blood pressure in patients who are not adequately controlled on other drugs. Hypertension. The durable efficacy was achieved with a good safety and tolerability profile.

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Multimorbidity Patterns and In‐Hospital Outcomes in Chinese Young Women (Aged <55 Years) Presenting with ST‐Segment–Elevation Myocardial Infarction

Journal of the American Heart Association

BackgroundRecent evidence highlights an increasing incidence of myocardial infarction in young women. years]) admitted to the China Chest Pain Center Database between 2016 and 2021. Among 9570 patients, 50% (n=4789) had multimorbidity.

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Why the sudden shock after a few days of malaise?

Dr. Smith's ECG Blog

This is a value typical for a large subacute MI, n ormal value 48 hours after myocardial infarction is associated with Post-Infarction Regional Pericarditis ( PIRP ). Mechanical complications secondary to myocardial infarction are infrequent due to most patients receiving revascularization quite rapidly.

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Protruding Aortic Plaque and Coronary Plaque Vulnerability

Journal of the American Heart Association

615 patients, the 186 (30.2%) patients with protruding aortic plaque were older and had more comorbidities such as hypertension, chronic kidney disease, and a prior myocardial infarction than those without.

Plaque 45
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Prediction of In?Hospital Mortality for Ischemic Cardiogenic Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation

Journal of the American Heart Association

Fifteen parameters were selected to assess in‐hospital mortality. The developed model was validated internally and externally using an independent external cohort (n=138). The developed model was validated internally and externally using an independent external cohort (n=138). Among 322 patients, 138 (42.9%) survived postdischarge.

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Abstract 52: Glucagon-like peptide-1 receptor agonists use and outcomes in Cardiac Amyloidosis patients: A Propensity Matched Analysis

Stroke Journal

Propensity score-matched analysis (PSM) (1:1) was performed with matching for age, gender, race, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, low-density lipid (LDL) level, left ventricular ejection fraction, and various drugs including ACEi, ARBi, ARNI, beta-blockers, and diuretics.

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National A-Fib Numbers Higher Than Previously Thought

DAIC

A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. million U.S. adults, according to new estimates from University of California-San Francisco. Earlier projections had estimated that 3.3