Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP115-ATP115, February 1, 2024. Background:The SouthEast Texas Regional Advisory Council (SETRAC) has actively engaged representatives from regional healthcare systems who collectively work towards advancing stroke care delivery. The rates of thrombolysis increased from 7.10% in 2014 to 11.8%

Thrombolysis

Journal of the American Heart Association

DECEMBER 24, 2024

Journal of the American Heart Association, Ahead of Print.

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP33-ATMP33, February 1, 2025. Introduction:Acute ischemic stroke (AIS) with large vessel occlusion (LVO) benefits from mechanical thrombectomy (MT), but the majority of Americans require interhospital transfer for MT. The mean time from LKN to thrombolysis was 2.2 years (range, 25.1

Thrombolysis

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP16-AWP16, February 1, 2024. Introduction:Trials using advanced imaging have shown a benefit from intravenous thrombolysis in patients with wake-up stroke, but real-world data is limited. in those able to receive perfusion imaging). in those able to receive perfusion imaging).

Thrombolysis

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP100-AWP100, February 1, 2024. Introduction:IV thrombolysis is a proven treatment for acute ischemic stroke (AIS), but it is still underutilized in real-world clinical practice. years, and the median time from onset to hospital arrival increased over the 10-year period.

Thrombolysis

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A43-A43, February 1, 2024. hours of ischemic stroke onset from 2003 to 2021. hours of ischemic stroke onset from 2003 to 2021. Thrombolysis rates and speed of treatment during TS phase I (2010-2013), II (2014-2018), and III (2019-2021) were compared with the pre-TS period (2003-2009).Results:Among

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP13-AWP13, February 1, 2025. Introduction:Strokes affecting the posterior circulation (PCS) account for 20% of all ischemic strokes. The number of stroke mimics presenting with isolated dizziness who received thrombolysis was 11 in 2021, 16 in 2022, 9 in 2023, and 11 in 2024.

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP1-ADP1, February 1, 2025. Whether intravenous thrombolysis (IVT) is safe and effective for acute ischemic stroke (AIS) patients with CAA is largely unknown.Methods:This was an explorative analysis of a nationwide database of hospitalizations in the United States. 4.16], p=0.001).

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A4-A4, February 1, 2025. Introduction:The tenecteplase versus standard of care for minor ischemic stroke with proven occlusion (TEMPO-2) trial showed that patients presenting with minor deficits up to 12 h do not benefit from intravenous thrombolysis. vs control 2.1%, P=0.005.

Thrombolysis

Stroke: Vascular and Interventional Neurology

MARCH 8, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. Among 51% of countries surveyed, no acute thrombolytic treatment was provided for acute stroke in the 2021 calendar year. Most respondents (88%) agreed there were barriers to acute stroke thrombolysis in the region.

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP20-ATP20, February 1, 2025. The primary outcome was 3-month functional outcome by modified Rankin scale (mRS). Patients with elevated traditional risk factors at admission may benefit more from thrombolytic therapy compared to those with high inflammatory response indicators.

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP8-AWP8, February 1, 2025. Introduction:Current guidelines recommend 24-hours of high-intensity monitoring (HIM) for acute ischemic stroke patients post-intravenous thrombolysis (IVT) due to risk of bleeding complications including symptomatic intracranial hemorrhage (sICH).

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP26-ATMP26, February 1, 2025. Introduction:Telestroke has the potential to revolutionize acute stroke treatment by improving access to optimal stroke care, including time-sensitive care such as thrombolysis. Telestroke patients were more commonly at primary stroke centers (71.1%

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP354-AWP354, February 1, 2025. Background:Circulating neuroinflammatory factors change rapidly in acute stroke, but the association with ischemic lesion size and stroke severity is unknown. Blood was obtained on the MSU, in the hospital, and from healthy adult controls.

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP115-ATP115, February 1, 2025. Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT).

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP256-AWP256, February 1, 2025. Introduction:In acute stroke patients who receive revascularization with endovascular thrombectomy (EVT) alone vs intravenous thrombolysis (IVT) followed by EVT, combination treatment has shown improved outcomes measured by the modified Rankin Scale (mRS).

Thrombolysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP53-AWMP53, February 1, 2025. Background:Treatment options and outcomes in stroke also depends on pre-hospital delays. Compared to the patients who reached by non-EMS mode, patients who reached by EMS mode were more likely to receive intravenous thrombolysis (16% vs 44%,).

Hospital

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A1-A1, February 1, 2024. Background:Enrollment into hyperacute stroke trials may be constrained since candidates are usually not identified until they arrive in the emergency department. patients per month compared to 2.4 after intervention (12/2021 - 07/2023), 2.43, 95% CI: 1.48-4.10,

Hospital

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP84-ATP84, February 1, 2025. Access to acute stroke care varies widely worldwide, with significant gaps in low- and middle-income countries and in rural areas. Ensuring equitable access requires a standardized approach to identify current coverage and potential sites for new stroke centers.

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP108-AWP108, February 1, 2025. Background:Emergency medical services (EMS) routing of stroke patients is challenging in rural settings. Optimal hospital destinations were selected for 310/499 (62.1%) patients prior to the protocol and 86/117 (73.5%) after (p=0.021).

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP91-AWP91, February 1, 2025. Introduction:Education campaigns have previously successfully informed the public regarding stroke symptoms and the need for urgent evaluation of suspected stroke. received thrombolysis and 53.6%

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP70-AWP70, February 1, 2025. Background:Every minute is crucial in treating acute ischemic stroke (AIS), as the effectiveness of intravenous thrombolysis and endovascular therapy is highly time-dependent. Ongoing enhancements in nurse training, communication, and support are needed.

Academic

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. Introduction:Many patients are taking antiplatelet medications when an acute stroke occurs. The exposure of interest was pre-stroke antiplatelet use categorized as none, single (SAPT), and dual antiplatelet therapy (DAPT). no antiplatelet, 36.7% SAPT, and 6.4%

Hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP3-AWP3, February 1, 2025. Introduction:Large vessel recanalization (LVR) is a well described phenomenon following intravenous thrombolysis (IVT). LVR patients had lower NIH Stroke Scale (p=0.006) and higher Tan CS (p=0.019). 0.90], p=0.024).

Thrombolysis

Stroke: Vascular and Interventional Neurology

SEPTEMBER 12, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundIt is unclear whether all patient subgroups with acute ischemic stroke have benefited from advances in reperfusion therapy. In patients with NIHSS score ≥10, intravenous thrombolysis frequency increased from 1.6%

Stroke

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A106-A106, February 1, 2024. Background:Circulating interleukin-6 (IL-6) concentrations are elevated in acute stroke but the timing of the IL-6 response in humans is unknown. We used a mobile stroke unit (MSU) to identify IL-6 levels within minutes of symptom onset. pg/mL, respectively.

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP72-AWP72, February 1, 2025. Background:Our system, comprised of 21 Northeast Ohio hospitals includes 3 Stroke Ready, 10 Primary and 1 Comprehensive Stroke Center (CSC). Alteplase remained on formulary for pediatric stroke and other diagnoses.

Stroke

Journal of the American Heart Association

MARCH 26, 2025

BackgroundStructural racism and rural/urban differences in stroke care affect care delivery and outcomes. We explored the interplay among structural racism, urbanity, and intravenous thrombolysis (tissue plasminogen activator) and endovascular thrombectomy (ET).Methods versus 88.6%), stroke certification (5.3% versus 0.11

Stroke

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP282-ATP282, February 1, 2024. Background:This analysis is based on a prospective database encompassing consecutive patients who underwent EVT for LVO between January 2021 and June 2023 at a comprehensive stroke center (CSC).Main vs. 70.6 ± 14.5).

Stroke

Stroke Journal

MARCH 14, 2025

Stroke, Ahead of Print. BACKGROUND:Providing equitable health care to rural stroke patients is challenging and associated with less intervention and poorer outcomes. Process outcomes included achievement of a stroke care bundle and thrombolysis administration.

Stroke

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionImportance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA).

Hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP43-ADP43, February 1, 2025. Objective:Most patients with concern for an acute stroke are transported by Emergency Medical Services (EMS) or a Mobile Stroke Unit (MSU) from community hospitals to a Comprehensive Stroke Center (CSC).

Stroke

Circulation

OCTOBER 19, 2023

BACKGROUND:The thrombectomy-capable stroke center (TSC) is a recently introduced intermediate tier of accreditation for hospitals at which patients with acute ischemic stroke receive care. Participants were recruited from Get With The Guidelines–Stroke registry. 1.66]) and in TSCs compared with PSCs (OR, 1.45 [95% CI, 1.08–1.96]).

Stroke

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A89-A89, February 1, 2024. Background and Aims:Treatment options for acute ischemic stroke (AIS) are uniquely dependent on the time of stroke onset. Intravenous thrombolysis must be administered within 4.5 Intravenous thrombolysis must be administered within 4.5 at <4.5

Stroke

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A13-A13, February 1, 2024. Background:Patients with acute ischemic stroke harboring a large vessel occlusion (LVO) admitted to non endovascular-capable centers often require inter-hospital transfer for thrombectomy.

Hospital

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP303-AWP303, February 1, 2025. Introduction:Significant strides have been made in optimizing thrombolysis and thrombectomy for acute ischemic stroke treatment. Prolonged arrival time was defined as more than 6 hours from the approximate last known well time. of prolonged arrivals.

Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AHUP15-AHUP15, February 1, 2025. Introduction:Late complications after stroke (LCAS), including cognitive symptoms, impact quality of life and recovery. It is not known if neighborhood-level measures of socioeconomic status (SES) influence LCAS.

Stroke