The British Journal of Cardiology

AUGUST 14, 2024

Faculty member Affiliation Professor Amitava Banerjee Professor of Clinical Data Science, Institute of Health Informatics, University College London; Consultant Cardiologist, University College London Hospitals and Barts Health NHS Trust Professor Sir Mark Caulfield Professor of Clinical Pharmacology, Queen Mary Un.

Cardiovascular Disease 40

Cardiovascular Disease Patient Care Innovation Pharmacology 40

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

The secondary objectives were to determine the differences in HF functional class, pharmacological therapy and evaluate the prognostic value of MAGGIC Score in this population. Methods We analyzed 1,556 medical records from the HF outpatient clinic of a quaternary hospital and 242 were selected according to the criteria.

Outpatient 59

Outpatient Obesity Heart Failure BMI 59

HeartRhythm

AUGUST 31, 2024

National guidelines now emphasize the use of pharmacologic cardioversion using antiarrhythmic drugs (AADs) as a key management strategy for patients with atrial fibrillation (AF). dofetilide, sotalol) are challenging for both patients and hospitals alike due to the need for cardiac monitoring to prevent Torsades de Pointes (TdP).

Atrial Fibrillation 40

Atrial Fibrillation Pharmacology Hospital 40

Journal of Cardiovascular Pharmacology

JUNE 24, 2024

Most recently, empagliflozin has been recently tested in patients with recent myocardial infarction in the EMPAgliflozin on Hospitalization for Heart Failure and Mortality in Patients With aCuTe Myocardial Infarction (EMPACT-MI) randomized trial, with apparently ambiguous findings.

Myocardial Infarction 40

Myocardial Infarction Heart Failure Pharmacology Diabetes 40

Open Heart

JUNE 29, 2023

Twenty-four of them avoided initial hospital admission as patients were directly enrolled to the virtual ward from outpatient settings. A rhythm control strategy was pursued in 82% (n=41) and 20% (n=10) required 3 or more remote pharmacological interventions. Methods An AF virtual ward was implemented as a proof-of-concept care model.

Atrial Fibrillation 52

Atrial Fibrillation COVID-19 Atrial Flutter Blood Pressure 52

Journal of the American Heart Association

DECEMBER 29, 2023

AF increases the risk of stroke, heart failure, dementia, and hospitalization. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited. Journal of the American Heart Association, Ahead of Print. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.

Obesity 45

Obesity Atrial Fibrillation Heart Failure Pharmacology 45

Journal of Cardiovascular Pharmacology

FEBRUARY 16, 2025

No abstract available

Hospital 40

Hospital 40

Dr. Smith's ECG Blog

FEBRUARY 8, 2015

The supposition that beta blockade in the presence of cocaine intoxication would lead to unopposed alpha constriction is not based in accurate pharmacology, and the study that showed this effect with human intracoronary administration was done, as mentioned in the article, with propranolol, a nonselective beta blocker. Henry Ford Hospital.

Tachycardia 52

Tachycardia Chest Pain Pharmacology Myocardial Infarction 52

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 6, 2024

The primary outcome was the percentage of patients receiving appropriate prophylaxis (high-risk patients with pharmacological thromboprophylaxis plus low-risk patients without prophylaxis) within 48 hours of hospitalization. We included consecutive general medical patients aged 18 years or older.

Pharmacology 40

Pharmacology Hospital Outcomes Circulation 40

DAIC

DECEMBER 22, 2023

Tricuspid regurgitation (TR) is a common and serious disease for which open heart surgery and symptomatic pharmacologic treatment are the current standard treatment options. Owing to high mortality risk, access to open heart surgery is severely restricted and is not considered an option for most patients with TR.

Tricuspid 59

Tricuspid Pacemaker Heart Valves Open-Heart Surgery 59

Cardiometabolic Health Congress

JANUARY 3, 2024

Knop, MD, PhD, professor of endocrinology and director of the Center for Clinical Metabolic Research at Gentofte Hospital, University of Copenhagen in Denmark, and consultant endocrinologist at Steno Diabetes Center in Copenhagen. Furthermore, most of the participants who were given survodutide 3.6 mg lost more than 15% of their body weight.

Obesity 97

Obesity Diabetes Blood Pressure BMI 97

Journal of Cardiovascular Pharmacology

OCTOBER 9, 2024

137 patients diagnosed with AF who presented with overt GIB were evaluated during their hospitalization, at one month and one year post-discharge, and then annually. 137 patients diagnosed with AF who presented with overt GIB were evaluated during their hospitalization, at one month and one year post-discharge, and then annually.

Atrial Fibrillation 40

Atrial Fibrillation Myocardial Infarction Kidney Disease Stents 40

Journal of Cardiovascular Pharmacology

DECEMBER 20, 2023

Methods: We retrospectively identified all patients admitted to our hospital in 2020 with decompensated systolic heart failure who were prescribed midodrine upon discharge. Survival at 6 months was similar between the two groups, but the midodrine group had more frequent re-hospitalization for heart failure. vs 11.6%; p=0.21).

Heart Failure 52

Heart Failure Hospital Outcomes Article 52

Journal of Cardiovascular Pharmacology

MARCH 5, 2024

Then, four databases were searched for randomized controlled trials that compared in-hospital mortality between an experimental group, with NAC, and a control group without NAC, in patients undergoing coronary catheterization or cardiac surgery. The primary efficacy outcome was in-hospital mortality. 0.92; P=0.02. 0.92; P=0.02.

Myocardial Infarction 40

Myocardial Infarction Hemorrhage Hospital Outcomes 40

Journal of Cardiovascular Pharmacology

NOVEMBER 16, 2023

The primary objective was to evaluate the association of serum albumin level with urine output (UOP) in hospitalized HF patients who received concomitant albumin and loop diuretic therapy. Secondary endpoints included total weight loss after 72-hours, and ICU and hospital lengths of stay. 276 patients were included for analysis.

Heart Failure 40

Heart Failure ICU Hospital Article 40

Journal of Cardiovascular Pharmacology

AUGUST 6, 2024

Guidelines recommend intravenous (IV) loop diuretics as first-line therapy for patients hospitalized with acute heart failure (AHF) and volume overload. We conducted a multi-center, retrospective cohort study of patients hospitalized with AHF and renal dysfunction who received metolazone or chlorothiazide in addition to IV loop diuretics.

Heart Failure 40

Heart Failure Hospital Article 40

Journal of Cardiovascular Pharmacology

OCTOBER 8, 2023

There were 22% lower odds of in-hospital/30-day mortality among patients who have used ACEi/ARBs in the past, (23.83% vs. 37.20%; OR 0.78, 95% CI 0.64-0.96) There was no significant difference in the length of hospital stay (MD 1.26, 95% CI -7.89 There was no significant difference in the length of hospital stay (MD 1.26, 95% CI -7.89

Outcomes 40

Outcomes Hospital Article 40

Journal of Cardiovascular Pharmacology

JANUARY 22, 2025

The primary outcome was the incidence of atrial fibrillation, while the secondary outcomes included other tachyarrhythmias, bradycardia, hypotension, duration of mechanical ventilation, time spent in the cardiac care unit, and length of hospitalization. A total of 101 patients were included in the DEX0.5 group (10.6% vs. 21.8%, P = 0.029).

Atrial Fibrillation 40

Atrial Fibrillation Bradycardia Outcomes Hospital 40

Journal of Cardiovascular Pharmacology

JANUARY 14, 2024

The primary aim of this study was to assess the impact of an immediate preloading strategy with ticagrelor on periprocedural myocardial injury in patients with NSTEMI treated with an early invasive strategy.

Myocardial Infarction 40

Myocardial Infarction Catheterization Laboratory Laboratory Hypertension 40

Journal of Cardiovascular Pharmacology

JUNE 27, 2012

Can Chen, Department of Cardiovascular disease, Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China, Telephone: +86-759-2369368, Fax: +86-759-2231754; E-mail: chencan-21@163.com The combination of Irbesartan and Emodin is better than single drug application. Correspondence to: Prof.

Hypertension 40

Hypertension Blood Pressure Document Cardiovascular Disease 40

Journal of Cardiovascular Pharmacology

FEBRUARY 13, 2022

Corresponding author: Lina Yang, Department of Nephrology, Yantai Yuhuangding Hospital, 20 Yuhuangding East Road, Yantai, Shandong, 264000, China Tel: +86 0535 6691999 83203; E-mail: ckocero@163.com This study suggested circ-GNB4 as a potential target to interfere the development of DN.

Diabetes 40

Diabetes Biomarkers Hospital Article 40

Dr. Smith's ECG Blog

APRIL 22, 2022

ST-elevation myocardial infarction after pharmacologic persantine stress test in a patient with Wellens’ syndrome. High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study. Lancet 2015 6. Patel J, Alattar F, Koneru J, et al. Case Rep Emerg Med 2014 7.

Chest Pain 52

Chest Pain Ischemia Myocardial Infarction Angina 52

Dr. Smith's ECG Blog

NOVEMBER 28, 2022

She was discharged after a short hospitalization with oncology and cardiology follow-up. At our hospital, I think all of our docs would want to place a pigtail catheter in the ED, under ultrasound guidance and not wait for cardiology to take the patient to the cath lab. A repeat POCUS showed resolution of her pericardial effusion.

Tachycardia 40

Tachycardia Pericarditis Ultrasound Blood Pressure 40

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

Author continued : STE in aVR is often due to left main coronary artery obstruction (OR 4.72), and is associated with in-hospital cardiovascular mortality (OR 5.58). 2 The astute paramedic recognized this possibility and announced a CODE STEMI. When pressors are not able to sustain blood pressure, balloon valvuloplasty may be considered.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

Surgical modifications and hemodynamic changes increase the susceptibility to arrhythmias, impacting morbidity and mortality rates, with arrhythmias being the leading cause of hospitalizations and sudden deaths. Pharmacological therapy involves antiarrhythmic and anticoagulant drugs, though data are limited with potential adverse effects.

Congenital Heart Disease 81

Congenital Heart Disease Congenital Heart Disease Arrhythmia 81

European Journal of Heart Failure

NOVEMBER 14, 2023

In the QUEST trial, QLQX reduced the combined risk of cardiovascular death or heart failure hospitalization (hazard ratio 0.78, 95% confidence interval 0.68–0.90), 0.90), based on 859 events in 3119 patients over a median of 18.2 months;

Heart Failure 40

Heart Failure Pharmacology Hospital Article 40

DAIC

APRIL 7, 2024

Akshay Desai, MD “Compared to placebo, a single injection of zilebesiran resulted in clinically meaningful reductions in blood pressure at three months when added to commonly used antihypertensive treatments,” said Akshay Desai, MD, MPH , a cardiologist at Brigham and Women’s Hospital in Boston and a study coauthor. “In

Blood Pressure 111

Blood Pressure Heart attacks Heart Attack Hypertension 111

DAIC

JULY 25, 2024

“The CardiAMP cell therapy has the potential to be groundbreaking and life changing for patients with heart failure,” said Dr. Leslie Miller, MD , trial investigator at the CHF Heart Function Clinic at BayCare Morton Plant Hospital in Clearwater, Florida and a member of the CardiAMP Heart Failure II Study Executive Steering Committee. “As

Heart Failure 111

Heart Failure Quality of Life CMS Reimbursement 111

DAIC

APRIL 11, 2024

At two years, people who underwent preventive PCI were 89% less likely to experience the composite primary endpoint of cardiac death, heart attack in the target vessel, revascularization due to ischemia in the target vessel or hospitalization for unstable or progressive chest pain compared with people who received medications alone.

Plaque 111

Plaque Heart attacks Heart Attack Coronary Artery Disease 111

Journal of Cardiovascular Pharmacology

FEBRUARY 9, 2025

This study aims to investigate the impact of in-hospital bleeding (IHB) at one-year follow-up in patients admitted for ACS. Acute coronary syndromes (ACS) continue to pose significant challenges for clinical practitioners, particularly regarding the prediction of mid- to long-term outcomes.

Peripheral Arterial Disease 40

Peripheral Arterial Disease Hospital Risk Factors Hypertension 40

Journal of Cardiovascular Pharmacology

SEPTEMBER 19, 2023

Venous thromboembolism (VTE) is a prevalent yet preventable cause of death, particularly among hospitalized patients. Betrixaban offers distinct pharmacological characteristics, including a long half-life, low renal excretion, and unique hepatic metabolism, making it an attractive option for various theoretical uses.

Article 40

Article Pharmacology Hospital 40

DAIC

DECEMBER 12, 2023

Wang’s research lab, which recently relocated to USF from Harvard Medical School where he was a professor working at Boston Children’s Hospital.

Heart attacks 105

Heart attacks Heart Attack Heart Disease Pharmacology 105

Journal of the American Heart Association

FEBRUARY 23, 2024

BackgroundThe effects of pharmacological therapy on cardiogenic shock (CS) survivors have not been extensively studied. Of 772 patients, 535 patients were enrolled in the present analysis following the exclusion of 217 in‐hospital deaths and 20 patients with missing medical records.

Cardiogenic Shock 40

Cardiogenic Shock Heart Failure Pharmacology Hospital 40

Open Heart

JULY 28, 2023

Conclusions This study is expected to provide valuable findings regarding arrhythmia in HFnon-rEF patients, and elucidate a potential new therapeutic approach for HFnon-rEF.

Atrial Fibrillation 40

Atrial Fibrillation Arrhythmia Heart Failure Tachycardia 40

DAIC

MAY 16, 2024

FAHA , co-director of the Vascular Center at the University Hospitals Harrington Heart & Vascular Institute and a professor of medicine at Case Western Reserve University School of Medicine , both in Cleveland, Ohio.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Smith's ECG Blog

APRIL 8, 2016

Crit Care Med 1991; 19:694) Concentrated Potassium Chloride Infusions in Critically Ill Patients with Hypokalemia The Journal of Clinical Pharmacology. Thus, hypokalemia is prevalent immediately after out-of-hospital cardiac arrest, whereas it is uncommon in AMI in the absence of cardiac arrest. However, the mean level (2.50.4

STEMI 52

STEMI Myocardial Infarction Cardiac Arrest Arrhythmia 52

Journal of Cardiovascular Pharmacology

MAY 23, 2024

Bleeding incidence and major adverse cardiovascular/cerebrovascular events (MACCE) were monitored during hospitalization, and at 1, 3, and 6 months post-surgery. The primary endpoints, including bleeding, mortality, and myocardial infarction during hospitalization, were not significant different between the two groups.

Myocardial Infarction 40

Myocardial Infarction STEMI Hospital Article 40