Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe use of detachable coils for endovascular embolization of cerebral aneurysms has become a safe and effective alternative to direct surgical clipping in patients with ruptured aneurysmal subarachnoid hemorrhage. In order to avoid thromboembolic complications in these cases, patients require treatment with antiplatelet therapy.

Aneurysm 40

Aneurysm Stents Stent Hemorrhage 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Both anticoagulants can be used intraoperatively and postoperatively for DVT prophylaxis in patients undergoing subarachnoid hemorrhage (SAH) treatment. This nationwide, multicenter, retrospective study provides valuable insights for clinicians on how to prevent and manage HIT in patients with subarachnoid hemorrhage.

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Thrombosis 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Exposure to high altitude environment is a risk factor of cerebral venous thrombosis (CVT) probably due to the hypercoagulability. Hemorrhage (44.2% Stroke, Volume 55, Issue Suppl_1 , Page ATP267-ATP267, February 1, 2024. The median age was 31 and 35 years old, and women accounted for 65.1% respectively. Headache (90.7%

Thrombosis 40

Thrombosis Risk Factors Hospital Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Background:Direct oral anticoagulants (DOACs) are suitable for some patients with cerebral venous thrombosis (CVT). The primary outcome at day 90 (D90) was a composite of CVT recurrence/extension and symptomatic intracranial hemorrhage (sICH). Stroke, Volume 55, Issue Suppl_1 , Page AWP149-AWP149, February 1, 2024. 1-4d, 23.8%

Thrombosis 40

Thrombosis Outcomes Hemorrhage Strokes 40

Stroke Journal

JANUARY 26, 2025

Neutrophil extracellular traps (NETs), associated with poor outcomes and reperfusion resistance, contribute to thrombosis. DNase-I, which degrades neutrophil extracellular traps, could improve thrombolytic efficacy.

Hemorrhage 40

Hemorrhage Strokes Stroke Thrombosis 40

Stroke Journal

FEBRUARY 1, 2024

Neutrophils are major contributors to cerebral thrombosis and oxidative stress following subarachnoid hemorrhage (SAH); however, the mechanism by which neutrophil integrin α9 contributes to SAH pathogenesis is unclear.

Hemorrhage 40

Hemorrhage Thrombosis Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

MRIs were scored as mild if there was isolated DMVT with no or only punctate parenchymal injury; moderate if there was DMVT with focal, unilateral ischemic or hemorrhagic injury, and severe if there was bilateral, confluent ischemic or hemorrhagic injury.

Thrombosis 40

Thrombosis Hemorrhage Congenital Outcomes 40

Stroke: Vascular and Interventional Neurology

OCTOBER 2, 2023

Safety outcomes included rates of symptomatic intracranial hemorrhage, parenchymal hematoma type 2, petechial hemorrhage, and in‐stent thrombosis. P=0.837), symptomatic intracranial hemorrhage–parenchymal hematoma type 2 (OR, 0.54 [95% CI, 0.05–4.98];P=0.589), 4.98];P=0.589), or petechial hemorrhage (OR, 1.11 [95% CI, 0.38–3.28];P=0.836).

Thrombosis 40

Thrombosis Hemorrhage Stents Stent 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionSubarachnoid Hemorrhage (SAH) resulting from the spontaneous rupture of an aneurysm is a rare and highly debilitating condition. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Hemorrhage 40

Hemorrhage Aneurysm Cardiac Arrest Myocardial Infarction 40

Stroke: Vascular and Interventional Neurology

AUGUST 26, 2024

The most common cerebrovascular disease complicating bacterial meningitis are cerebral infarctions (9%25%), intracerebral hemorrhage (1%7%), cerebral venous thrombosis (1%10%), and subarachnoid hemorrhage (1%5%).Streptococcus Cerebrovascular complications occur in one fourth of patients with bacterial meningitis.

Cerebrovascular Disease 40

Cerebrovascular Disease Thrombosis Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Stroke is a leading cause of maternal morbidity and mortality, and hemorrhagic strokes account for up to half of these cases. Patients with insufficient data for a determination were categorized as no diagnostic delay.Results:A total of 121 patients were identified, of whom 48% had hemorrhagic stroke.

Strokes 40

Strokes Stroke Hemorrhage Thrombosis 40

Stroke Journal

NOVEMBER 27, 2024

BACKGROUND:Lack of a dedicated thrombectomy device for cerebral venous thrombosis hinders the recanalization ability of endovascular treatment (EVT). Safety outcomes included peri-procedural complications, all-cause mortality, and symptomatic intracranial hemorrhage after EVT.RESULTS:A total of 61 patients were enrolled and randomized.

Thrombosis 40

Thrombosis Stent Stents Hemorrhage 40

Stroke Journal

MARCH 11, 2024

Historically, the research literature overwhelmingly emphasized the future hemorrhagic risk associated with CMBs, potentially leading to unnecessary withholding of treatments proven effective at preventing thrombosis, such as anticoagulants in patients with atrial fibrillation who happened to have some microbleeds.

Hemorrhage 40

Hemorrhage Atrial Fibrillation Thrombosis Article 40

Stroke Journal

FEBRUARY 1, 2024

In severe OHSS, increases in capillary permeability can result in hemoconcentration and hypercoagulability leading to thrombotic events, including stroke and cerebral venous thrombosis. Within the HCUP cohort, fewer than 10 patients (<1%) were hospitalized with a stroke or thrombotic event within 60 days of OHSS diagnosis.

Thrombosis 40

Thrombosis Inpatient Embolism Myocardial Infarction 40

Journal of the American Heart Association

JANUARY 10, 2025

Bleeds were adjudicated using International Society on Thrombosis and Haemostasis criteria. Patients with intracranial hemorrhage during followup were excluded; those with >1 bleeding event were categorized according to their most severe event. The safety cohort with interval censoring during drug interruption was analyzed.

Atrial Fibrillation 40

Atrial Fibrillation Thrombosis Myocardial Infarction Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Eligible patients were between ages 18-50 years, with a confirmed diagnosis of arterial ischemic stroke (AIS), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH) or cerebral venous thrombosis (CVT) between 01/01/2012 and 12/31/2021.

Strokes 40

Strokes Stroke Hemorrhage Thrombosis 40

Stroke Journal

FEBRUARY 1, 2024

vs. 6.1%, p = 0.0002), deep vein thrombosis (7.3 vs. 6.1%, p = 0.0326), and symptomatic intracerebral hemorrhage (7.3% p = 0.0027), and symptomatic intracranial hemorrhage (OR 5.2, Prolonged ICU stay were more likely to have higher baseline median NIHSS score (19 vs. 14%, p < 0.0001), posterior circulation stroke (12.6%

ICU 40

ICU Thrombolysis Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Secondary outcomes were the scores of National Institutes of Health Stroke Scale (NIHSS) and Barthel index (BI), stroke recurrence, overall mortality and the occurrence of vascular events by 3 months (recurrent stroke, acute coronary syndrome, deep vein thrombosis and hemorrhagic transformation or intracerebral hemorrhage).Results:In

Strokes 40

Strokes Stroke Hemorrhage Thrombosis 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

We therefore aim to characterize the antiplatelet regimens, and associated thromboembolic/hemorrhagic outcomes, utilized in patients with aneurysms treated with PED Shield.MethodsFactors including demographics, comorbidities, rupture status, devices placed, and antiplatelet regimen, among others, were collected.

Embolism 40

Embolism Aneurysm Hemorrhage Stents 40

Stroke Journal

FEBRUARY 1, 2024

Cases had a maternal stroke (ischemic, hemorrhagic, subarachnoid hemorrhage, or cerebral venous thrombosis) during pregnancy or PP, identified from a stroke registry.

Hypertension 40

Hypertension Strokes Stroke Blood Pressure 40

Stroke Journal

JANUARY 30, 2025

Topics covered included early recognition, acute management, hemorrhagic stroke, cerebral venous sinus thrombosis (CVST), etc. Each poster was designed to be visually engaging and included a QR code to lead the participant to an interactive quiz with five content-related questions.

Education 40

Education Strokes Stroke Certification 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The suggested DCV pathophysiologic mechanisms involve vascular inflammation and delayed cerebral thrombosis (DCT). Intra‐arterial and intravenous Milrinone, a phosphodiesterase‐3 inhibitor, showed benefits in subarachnoid hemorrhage‐associated vasospasm, and it was used in DCV with observed benefits.

Thrombosis 40

Thrombosis Risk Factors Research Hemorrhage 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

In light of postoperative CT head showing SAH in the basilar, perimesencephalic, prepontine cisterns, interhemispheric fissure and right frontal sulci as well as intraventricular hemorrhage in fourth ventricle, her presentation was thought to be secondary to cerebral vasospasm in the setting of postoperative SAH.

Blood Pressure 40

Blood Pressure Stenosis Hemorrhage Thrombosis 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The use of recreational cocaine in young adults is well known to be responsible for acute ischemic and hemorrhagic strokes in individuals who lack other vascular risk factors. What is significantly rarer with few reported cases, however, is cocaine‐related ASCIS as the etiology of non‐traumatic acute spinal cord myelopathy [3‐7].MethodsN/AResultsA

Ischemia 40

Ischemia Myocardial Infarction Thrombosis Document 40

Dr. Smith's ECG Blog

JULY 22, 2012

Blunt cardiac injury my result in : 1) Acute myocardial rupture with tamponade 2) Valve rupture (tricuspid, aortic, mitral) 3) Coronary thrombosis or dissection (and thus Acute MI) from direct coronary blunt injury 4) Dysrhythmias of all kinds.

Dysrhythmia 52

Dysrhythmia Biomarkers Echocardiogram Ultrasound 52

Dr. Smith's ECG Blog

NOVEMBER 4, 2022

Widespread ST-depression with reciprocal aVR ST-elevation can be cause by: Heart rate related: tachyarrhythmia (e.g., Initial blood work showed the following: metabolic acidosis on VBG with a lactate of 7.1;

Ischemia 52

Ischemia STEMI Stenosis Chest Pain 52

Stroke Journal

FEBRUARY 1, 2024

A point-scoring system was generated by the β-coefficients of the variables independently associated with the long-term risk of arterial thrombosis, and the predictive MUCH score was calculated as the sum of the weighted scores.RESULTS:Overall, 1729 patients (median follow-up time, 43 months [25th to 75th percentile, 69.0]) qualified for inclusion.

Thrombosis 40

Thrombosis Hemorrhage Coronary Artery Disease Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

Background:Prognostication following cerebral venous thrombosis (CVT) remains challenging. Stroke, Volume 55, Issue Suppl_1 , Page ATMP108-ATMP108, February 1, 2024. Mortality is an uncommon yet catastrophic outcome after CVT. ACTION-CVT was an international retrospective study that enrolled consecutive patients with CVT across 27 centers.

Thrombosis 40

Thrombosis Risk Factors Hemorrhage Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:COVID-19 infection has thus emerged to be a new risk factor for Cerebral Venous Thrombosis (CVT). Acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), epilepsy, deep vein thrombosis and pulmonary embolism were secondary outcomes. vs 5.5%; HR=2.16; 95% CI=1.23-3.64

COVID-19 40

COVID-19 Outcomes Thrombosis Embolism 40

Stroke Journal

JANUARY 30, 2025

proposed an innovative thromboembolic stroke model in mice where murine thrombin is injected into the M2 segment of the middle cerebral artery (MCA) to induce arterial thrombosis. We compared the effects of Alteplase in thrombin-model with FeCl3-induced thrombosis model. Introduction:In 2007, Orset et al.

Pharmacology 40

Pharmacology Strokes Stroke Thrombosis 40

Stroke Journal

DECEMBER 9, 2024

Anticardiolipin antibodies, anti-2-glycoprotein I antibodies, and lupus anticoagulant were assessed using the guidelines of the International Society on Thrombosis and Haemostasis.RESULTS:aPL prevalence was 22% in patients with MMA and 25% in controls (P=0.74) with no differences in aPL subtypes between the 2 groups.

Cerebrovascular Disease 40

Cerebrovascular Disease Thrombosis Hemorrhage Strokes 40

Stroke Journal

JANUARY 21, 2024

Men exhibited more unstable plaques (P<0.001), characterized by increased plaque hemorrhage, larger lipid core, and inflammation (P<0.001), along with less favorable circulating profiles. years), the final study analyses included 317 men and 143 women (aged 71.0±9.0

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Plaque Circulation Atherosclerosis Hemorrhage 40