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Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. vs. 0.4%) and 4X ischemic stroke rates (csHR = 4.06). year follow-up. per 100 person-year.
Stroke, Ahead of Print. We sought to explore the relationship between ART and stroke risk using population-level data.Methods:We conducted a retrospective cohort study using data from the National Inpatient Sample (NIS) registry from 2015-2020, including all delivery hospitalizations for patients aged 15-55 years. 100,000 vs. 9.1/100,000),
Stroke, Volume 55, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2024. Introduction:Deep medullary vein(DMV) thrombosis is a rare cause of neurological damage noted in both term and preterm infants. The spectrum of parenchymal radiological findings in DMV thrombosis includes edema and hemorrhage of variable extent.
Stroke, Volume 56, Issue 2 , Page 527-532, February 1, 2025. BACKGROUND:Acute ischemic stroke treatment typically involves tissue-type plasminogen activator (tPA) or tenecteplase, but about 50% of patients do not achieve successful reperfusion. DNase-I, which degrades neutrophil extracellular traps, could improve thrombolytic efficacy.
Stroke, Volume 56, Issue Suppl_1 , Page ATP201-ATP201, February 1, 2025. Background:Patients with intracerebral hemorrhage (ICH) are known to have a higher risk of venous thromboembolism (VTE) than patients with acute ischemic stroke, but the factors underlying this difference have not been clearly identified.
Stroke, Volume 55, Issue Suppl_1 , Page ATP180-ATP180, February 1, 2024. Background:Coronavirus disease 2019 (COVID-19) increases the risk of cerebral venous sinus thrombosis (CVST), and previous reports derived from small case series reported a high mortality in these patients, up to 40%.
Stroke, Volume 56, Issue Suppl_1 , Page AWP134-AWP134, February 1, 2025. Introduction:Stroke is a leading cause of maternal morbidity and mortality, and hemorrhagicstrokes account for up to half of these cases. Prior studies in non-maternal populations demonstrated that 9% of strokes are missed at initial ED presentation.
Stroke, Volume 56, Issue Suppl_1 , Page A151-A151, February 1, 2025. Introduction:Stroke is a leading cause of maternal morbidity and mortality, and the incidence of maternal stroke is triple that of age-matched, non-pregnant counterparts. Characteristics of the study population are shown in the Table.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP62-ATMP62, February 1, 2024. Introduction:Seizures are a common initial manifestation of cerebral venous thrombosis (CVT). Risk factors included intracranial hemorrhage (OR 2.0 The primary outcome was delayed seizure(s), occurring after 7 days from CVT diagnosis.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionUp to 18% of spontaneous intracerebral hemorrhages are cryptogenic despite a thorough workup, usually noted in a lobar location. CT revealed a left parasagittal hemorrhage. CT revealed a right parasagittal hemorrhage.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Both anticoagulants can be used intraoperatively and postoperatively for DVT prophylaxis in patients undergoing subarachnoid hemorrhage (SAH) treatment. SAH severity was determined using the National Institute of Health Stroke Scale as a template.
Stroke, Volume 55, Issue Suppl_1 , Page AWP149-AWP149, February 1, 2024. Background:Direct oral anticoagulants (DOACs) are suitable for some patients with cerebral venous thrombosis (CVT). The primary outcome at day 90 (D90) was a composite of CVT recurrence/extension and symptomatic intracranial hemorrhage (sICH). 1-4d, 23.8%
Stroke, Volume 56, Issue Suppl_1 , Page AWMP59-AWMP59, February 1, 2025. Background and Purpose:External counterpulsation (ECP) is a novel noninvasive method used to improve the perfusion of vital organs, which may benefit ischemic stroke patients. of 65 patients in ECP group compared to 9.1%
Stroke, Volume 55, Issue Suppl_1 , Page AWP259-AWP259, February 1, 2024. Cases had a maternal stroke (ischemic, hemorrhagic, subarachnoid hemorrhage, or cerebral venous thrombosis) during pregnancy or PP, identified from a stroke registry. Population characteristics are shown in the Table.
Stroke, Volume 56, Issue Suppl_1 , Page ATP67-ATP67, February 1, 2025. Introduction:Ongoing staff stroke education is crucial to ensure that stroke knowledge remains current and at the forefront of everyone's minds and is also required for stroke certification.
Stroke, Volume 55, Issue Suppl_1 , Page AWP154-AWP154, February 1, 2024. Prolonged ICU stay were more likely to have higher baseline median NIHSS score (19 vs. 14%, p < 0.0001), posterior circulation stroke (12.6% vs. 6.1%, p = 0.0002), deep vein thrombosis (7.3 vs. 6.1%, p = 0.0002), deep vein thrombosis (7.3
Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundProcedural intravenous cangrelor has been proposed as an effective platelet inhibition strategy for stenting in acute ischemic stroke. P=0.837), symptomatic intracranial hemorrhage–parenchymal hematoma type 2 (OR, 0.54 [95% CI, 0.05–4.98];P=0.589),
Stroke, Volume 55, Issue Suppl_1 , Page A16-A16, February 1, 2024. Neutrophils are major contributors to cerebral thrombosis and oxidative stress following subarachnoid hemorrhage (SAH); however, the mechanism by which neutrophil integrin α9 contributes to SAH pathogenesis is unclear.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP85-ATMP85, February 1, 2025. MRIs were scored as mild if there was isolated DMVT with no or only punctate parenchymal injury; moderate if there was DMVT with focal, unilateral ischemic or hemorrhagic injury, and severe if there was bilateral, confluent ischemic or hemorrhagic injury.
Stroke, Ahead of Print. Historically, the research literature overwhelmingly emphasized the future hemorrhagic risk associated with CMBs, potentially leading to unnecessary withholding of treatments proven effective at preventing thrombosis, such as anticoagulants in patients with atrial fibrillation who happened to have some microbleeds.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionSubarachnoid Hemorrhage (SAH) resulting from the spontaneous rupture of an aneurysm is a rare and highly debilitating condition.
Stroke, Volume 55, Issue Suppl_1 , Page A134-A134, February 1, 2024. In severe OHSS, increases in capillary permeability can result in hemoconcentration and hypercoagulability leading to thrombotic events, including stroke and cerebral venous thrombosis. were included from each dataset.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Seven patients had strokes of any kind, three of which were unrelated to the treatment territory, and two of the remaining 4 were non‐compliant with antiplatelet therapy. One patient had a new intraparenchymal hemorrhage, but no appreciable deficit.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. The suggested DCV pathophysiologic mechanisms involve vascular inflammation and delayed cerebral thrombosis (DCT). Intra‐arterial and intrathecal vasodilators have been reportedly used with variable outcomes.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. She was noted to have incidental left internal jugular (IJ) vein thrombosis for which anticoagulation was held in the setting of recent neurosurgical procedure and SAH. Cerebral vasospasm following EEA has rarely been described.
Stroke, Ahead of Print. Primary end point was a composite of ischemic stroke, myocardial infarction, or other arterial thrombotic events. Primary end point was a composite of ischemic stroke, myocardial infarction, or other arterial thrombotic events. 0.81) for the 0- to 1-year score, 0.672 (95% CI, 0.58–0.73)
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe use of detachable coils for endovascular embolization of cerebral aneurysms has become a safe and effective alternative to direct surgical clipping in patients with ruptured aneurysmal subarachnoid hemorrhage.
Stroke, Volume 56, Issue Suppl_1 , Page AWP364-AWP364, February 1, 2025. proposed an innovative thromboembolic stroke model in mice where murine thrombin is injected into the M2 segment of the middle cerebral artery (MCA) to induce arterial thrombosis. Introduction:In 2007, Orset et al.
Stroke, Volume 55, Issue Suppl_1 , Page ATP267-ATP267, February 1, 2024. Introduction:Exposure to high altitude environment is a risk factor of cerebral venous thrombosis (CVT) probably due to the hypercoagulability. Hemorrhage (44.2% The median age was 31 and 35 years old, and women accounted for 65.1% respectively.
Stroke: Vascular and Interventional Neurology, Ahead of Print. The most common cerebrovascular disease complicating bacterial meningitis are cerebral infarctions (9%25%), intracerebral hemorrhage (1%7%), cerebral venous thrombosis (1%10%), and subarachnoid hemorrhage (1%5%).Streptococcus
Stroke, Volume 56, Issue 1 , Page 190-193, January 1, 2025. The prevalence of transient ischemic attacks, ischemic stroke, and hemorrhagicstroke did not differ between patients with aPL-positive and aPL-negative MMA.CONCLUSIONS:The prevalence of aPL in patients with MMA is comparable to that in non-MMA controls.
Stroke, Volume 55, Issue 2 , Page 269-277, February 1, 2024. Men exhibited more unstable plaques (P<0.001), characterized by increased plaque hemorrhage, larger lipid core, and inflammation (P<0.001), along with less favorable circulating profiles. years), the final study analyses included 317 men and 143 women (aged 71.0±9.0
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. of all strokes [1, 2]. These strokes primarily occur in the anterior spinal cord artery (ASA) and/or the posterior spinal cord artery (PCA) territory and can have widely variable clinical presentation.
Stroke, Volume 55, Issue Suppl_1 , Page AWMP49-AWMP49, February 1, 2024. Introduction:COVID-19 infection has thus emerged to be a new risk factor for Cerebral Venous Thrombosis (CVT). CVT with COVID patients were more likely to develop deep vein thrombosis at one month (19.8% All-cause mortality was the primary outcome.
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