Remove Hemorrhage Remove Stroke Remove Thrombosis
article thumbnail

Abelacimab Stops Bleeding, But Stroke Impact Uncertain

CardiacWire

Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. vs. 0.4%) and 4X ischemic stroke rates (csHR = 4.06). year follow-up. per 100 person-year.

Stroke 59
article thumbnail

Association of Assisted Reproductive Technology and Stroke During Hospitalization for Delivery in the United States

Stroke Journal

Stroke, Ahead of Print. We sought to explore the relationship between ART and stroke risk using population-level data.Methods:We conducted a retrospective cohort study using data from the National Inpatient Sample (NIS) registry from 2015-2020, including all delivery hospitalizations for patients aged 15-55 years. 100,000 vs. 9.1/100,000),

article thumbnail

Abstract WP227: Deep Medullary Vein Thrombosis in Neonates

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2024. Introduction:Deep medullary vein(DMV) thrombosis is a rare cause of neurological damage noted in both term and preterm infants. The spectrum of parenchymal radiological findings in DMV thrombosis includes edema and hemorrhage of variable extent.

article thumbnail

Daytime DNase-I Administration Protects Mice From Ischemic Stroke Without Inducing Bleeding or tPA-Induced Hemorrhagic Transformation, Even With Aspirin Pretreatment

Stroke Journal

Stroke, Volume 56, Issue 2 , Page 527-532, February 1, 2025. BACKGROUND:Acute ischemic stroke treatment typically involves tissue-type plasminogen activator (tPA) or tenecteplase, but about 50% of patients do not achieve successful reperfusion. DNase-I, which degrades neutrophil extracellular traps, could improve thrombolytic efficacy.

article thumbnail

Abstract TP201: Factors associated with development of venous thromboembolism in patients with intracranial hemorrhage.

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP201-ATP201, February 1, 2025. Background:Patients with intracerebral hemorrhage (ICH) are known to have a higher risk of venous thromboembolism (VTE) than patients with acute ischemic stroke, but the factors underlying this difference have not been clearly identified.

article thumbnail

Abstract TP180: Characteristics and Outcomes of Cerebral Venous Sinus Thrombosis Associated With COVID-19

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page ATP180-ATP180, February 1, 2024. Background:Coronavirus disease 2019 (COVID-19) increases the risk of cerebral venous sinus thrombosis (CVST), and previous reports derived from small case series reported a high mortality in these patients, up to 40%.

article thumbnail

Abstract WP134: Stroke Subtype is Associated with Diagnostic Delays in Pregnancy and Postpartum: A Retrospective Study

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP134-AWP134, February 1, 2025. Introduction:Stroke is a leading cause of maternal morbidity and mortality, and hemorrhagic strokes account for up to half of these cases. Prior studies in non-maternal populations demonstrated that 9% of strokes are missed at initial ED presentation.

Stroke 40