Science Daily - Stroke

MAY 22, 2024

Extreme heat and extreme cold are both associated with increased risks of death from ischemic and hemorrhagic stroke, according to a new study. The researchers found that the link between extreme temperatures and stroke mortality was stronger in low-income countries than in high-income countries.

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Stroke Strokes Hemorrhage Research 107

Stroke Journal

OCTOBER 2, 2024

Stroke, Ahead of Print. BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). Of the 1104 patients, 268 (24.3%) had AA-ICH: 148 (55.2%) with vitamin K antagonists and 107 (39.9%) with direct oral anticoagulants.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP164-AWP164, February 1, 2024. Introduction:Patients who have had hemorrhagic strokes experience psychological and functional deficits after hospital discharge. Conclusion:Psychological and functional outcomes for patients with hemorrhagic strokes are associated with SDoH.

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NEJM Journal Watch - Cardiology

SEPTEMBER 30, 2024

A 14-day monitor detected more atrial fibrillation but did not affect hospitalization rates for stroke or hemorrhage.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP279-ATP279, February 1, 2024. Whether atrial cardiopathy is associated with the risk of intracranial hemorrhage in acute ischemic stroke (AIS) remains uncertain. Our primary outcomes included any intracranial hemorrhage (ICH) and symptomatic ICH (sICH) during follow-up.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP78-AWMP78, February 1, 2024. Introduction:Mobile stroke units (MSUs) are an evolving means to expedited acute stroke management. The target blood pressure goal was met much quicker in the MSU. Faster time metrics convey a hypothetical benefit towards improved patient outcomes.

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Circulation

NOVEMBER 11, 2024

Background:Following an ischemic stroke, a serious complication known as hemorrhagic transformation (HT) might jeopardize patient outcomes. Following an ischemic stroke, an increased incidence of HT, especially parenchymal hematoma (PH), has been associated with greater NLR.

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Medical Xpress - Cardiology

OCTOBER 31, 2024

Joseph Tarsia are co-authors on a post hoc analysis carried out in the ARCADIA randomized clinical trial, comparing the effectiveness of apixaban versus aspirin in preventing adverse clinical outcomes in patients with a history of cancer and cryptogenic stroke. The study was published in the JAMA Neurology journal.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP168-ATP168, February 1, 2024. Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. The primary outcome was coma (GCS ≤ 8) at time of admission. The median [IQR] ICH volume was 9.3

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP20-AWP20, February 1, 2024. Importance:Tenecteplase use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke, with results demonstrating its non-inferiority compared to alteplase. Results:Median age was 62.94 for alteplase and 64.45

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Stroke Journal

JANUARY 26, 2024

Stroke, Ahead of Print. BACKGROUND:The dynamics of blood clot (combination of Hb [hemoglobin], fibrin, and a higher concentration of aggregated red blood cells) formation within the hematoma of an intracerebral hemorrhage is not well understood.

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All About Cardiovascular System and Disorders

NOVEMBER 16, 2023

ECG Changes in Intracranial Hemorrhage ECG changes are fairly common in intracranial hemorrhage. Giant T inversions with QT interval prolongation may be seen in intracranial hemorrhage even without associated myocardial damage [1]. But the number of persons with lobar hemorrhage in that study was only 17%. Am Heart J.

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Hemorrhage Myocardial Infarction Aneurysm Electrocardiogram 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP81-ATMP81, February 1, 2024. Background and Purpose:Post thrombolytic intracerebral hemorrhage (ICH) is associated with higher rate of death or disability in acute ischemic stroke patients. Outcomes were determined by using utility weighted modified Rankin scale (UW-mRs) at 90-days.

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Journal of the American Heart Association

FEBRUARY 7, 2024

Among our several subgroup analyses, we looked at difference depending on stroke status and also depending on age. Overall, we found a higher risk of hemorrhagic stroke for LDL‐C lowering, risk ratio (RR) 1.16 (95% CI, 1.01–1.32,P=0.03). Journal of the American Heart Association, Ahead of Print. 1.73) (Pint=0.14

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A2-A2, February 1, 2024. Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. Introduction:Many patients are taking antiplatelet medications when an acute stroke occurs. The exposure of interest was pre-stroke antiplatelet use categorized as none, single (SAPT), and dual antiplatelet therapy (DAPT). no antiplatelet, 36.7% SAPT, and 6.4%

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DAIC

FEBRUARY 26, 2024

Kulcsar, University Hospital Zurich milla1cf Mon, 02/26/2024 - 12:13 February 26, 2024 — Ischemic strokes are a major health burden. Many stroke patients recover poorly despite timely treatment To treat these symptoms and restore blood flow to the brain, the obstructed vessel needs to be “declogged”, or recanalized.

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Blood Clot Stroke Strokes Outcomes 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP167-ATP167, February 1, 2024. Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] 1.10]), top-quartile hemorrhage volume (2.89 [1.08-7.75]),

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP224-ATP224, February 1, 2024. Myeloproliferative Neoplasms (MPNs) are rare acquired stem cell disorders, consisting of Essential Thrombocythemia (ET), Polycythemia Vera (PV), and Primary Myelofibrosis (PMF), complicated by thrombohemorrhagic events such as stroke.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP84-AWMP84, February 1, 2024. Concerns have been raised regarding their potential increased risk of bleeding complications including intracerebral hemorrhage (ICH) as they are known to affect platelet function. 14.45; 52% male), among those 14% had pre-morbid AD use (age 72.13±13.23,

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionImportance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA).

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntravenous thrombolytics (IVT) and mechanical thrombectomy (MT) have become the standards of care for treating patients with large vessel occlusion (LVO) acute ischemic strokes (AIS) [1‐4}. in a large multicentered meta‐analysis [2,6].

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Med Page Today

FEBRUARY 17, 2024

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP41-AWP41, February 1, 2024. Background:Intracerebral Hemorrhage (ICH) accounts for 10% of strokes and has higher risk for mortality and disability. Hematoma expansion may occur in ICH.

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American Heart News - Stroke News

FEBRUARY 1, 2024

Research Highlights: Among most ischemic (clot-caused) stroke survivors including those taking anticoagulant medications, use of antidepressants in the SSRI or SNRI class did not increase the risk of hemorrhagic (bleeds) stroke or other serious.

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Stroke Strokes Hemorrhage Research 75

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundAsymptomatic intracerebral hemorrhage (aICH) occurs in approximately 35% of patients with acute ischemic stroke after endovascular thrombectomy. Journal of the American Heart Association, Ahead of Print. Unlike symptomatic ICH, studies evaluating the effect of aICH on outcomes have been inconclusive.

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe routinely used computed tomography (CT)‐based workup in the setting of acute ischemic stroke (AIS) includes non‐contrast brain CT, CT angiography (CTA), and CT perfusion.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP156-AWP156, February 1, 2024. Outcomes were 1) infarct growth or recurrence, and 2) increased hemorrhagic transformation (HT) in follow-up MRI compared to the initial MRI. Background:Blood viscosity (BV) affects blood vessel wall shear stress. Each patient underwent initial and follow-up MRI.

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Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. 69.88];P = 0.04), respectively.CONCLUSION“Benign” perimesencephalic subarachnoid hemorrhage pattern was associated with a ruptured aneurysm in 6.2% RESULTSEighty‐one patients were included with mean age of 55.5 ± 10.3 104];P = 0.007, OR = 22.6 [4.2–123.5];P<0.001,

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP155-ATP155, February 1, 2024. Background:Hemorrhagic transformation (HT) is a critical sequela of acute ischemic stroke (AIS). Matrix metalloproteinase-9 (MMP-9) has been implicated in the pathophysiology of hemorrhagic transformation (HT) post-acute ischemic stroke (AIS).

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Stroke Journal

FEBRUARY 27, 2024

Stroke, Ahead of Print. Earlier SBP control was not associated with cardiac or renal adverse events.CONCLUSIONS:Our study confirms a clear time relation between early versus later SBP control (120–140 mm Hg) and outcomes in the one-third of patients with intracerebral hemorrhage who attained sustained SBP levels within this range.

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Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 50-58, January 1, 2024. BACKGROUND:The effect of marine omega-3 PUFAs on risk of stroke remains unclear.METHODS:We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic, and hemorrhagic) in 29 international prospective cohorts.

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Stroke Strokes Hemorrhage Circulation 74

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP56-ATMP56, February 1, 2024. Background:Mechanical revascularization has become an essential treatment for acute ischemic stroke patients. Post-treatment imaging frequently displays hyperdense regions, prompting concerns regarding possible cerebral hemorrhage.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP166-AWP166, February 1, 2024. Background:Early initiation of antidepressants (ADs) are associated with improved functional recovery, but are associated with an increased risk of major bleeds among hemorrhagic stroke (HS) patients.

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionHemorrhagic transformation is a major complication of large vessel occlusion (LVO) recanalization after mechanical thrombectomy in acute ischemic stroke. female), 55 (19%) had hemorrhagic transformation. to 15.18; p=0.011).ConclusionIn

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DAIC

FEBRUARY 8, 2024

Image courtesy: Getty Images christine.book Thu, 02/08/2024 - 15:53 February 8, 2024 — The latest late-breaking science from the second day of the American Stroke Association ’s International Stroke Conference , ISC 2024 , shed light on the use of artificial intelligence ( AI ) to help guide treatment decisions for stroke patients.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A150-A150, February 1, 2024. The PiB uptake was significantly higher in occipital lobes with hemorrhages compared to their contralateral lobes without hemorrhages (1.41±0.3 p=0.002, 1.28±0.1 p=0.004, 1.29±0.1 p=0.002, respectively) but not in parietal lobes (p=0.107). for all comparisons).Conclusions:Reduced

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