NEJM Journal Watch - Cardiology

SEPTEMBER 30, 2024

A 14-day monitor detected more atrial fibrillation but did not affect hospitalization rates for stroke or hemorrhage.

Atrial Fibrillation 84

Atrial Fibrillation Stroke Strokes Hemorrhage 84

DAIC

FEBRUARY 8, 2024

Image courtesy: Getty Images christine.book Thu, 02/08/2024 - 15:53 February 8, 2024 — The latest late-breaking science from the second day of the American Stroke Association ’s International Stroke Conference , ISC 2024 , shed light on the use of artificial intelligence ( AI ) to help guide treatment decisions for stroke patients.

Stroke 105

Stroke Strokes Research Heart Attack 105

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

The patient died 38 h after admission due to a second-stage subarachnoid hemorrhage associated with progressive DIC. Laboratory results revealed a rapidly progressing disseminated intravascular coagulation (“DIC”) and a clinically asymptomatic COVID-19 infection.

Hemorrhage 59

Hemorrhage COVID-19 Laboratory Stroke 59

American Heart News - Stroke News

FEBRUARY 1, 2024

Research Highlights: Among most ischemic (clot-caused) stroke survivors including those taking anticoagulant medications, use of antidepressants in the SSRI or SNRI class did not increase the risk of hemorrhagic (bleeds) stroke or other serious.

Stroke 79

Stroke Strokes Hemorrhage Research 79

DAIC

JUNE 3, 2024

Heuron ICH is an advanced AI solution designed to automatically screen and signal potential cases of intracranial hemorrhage, relying solely on non-contrast CT images. Notably, Heuron ICH boasts a sensitivity of 86% and specificity of 88%, ensuring reliable and accurate assistance in critical medical scenarios.

Certification 105

Certification Hemorrhage Stroke Strokes 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ANS7-ANS7, February 1, 2024. Project analysis began by identifying care opportunities. Development of such a process raised the standard of care for this patient population and leads to overall improvement in patient management.

Hemorrhage 40

Hemorrhage Stroke Strokes Best Practices 40

DAIC

FEBRUARY 9, 2024

announced the primary endpoint results of its EvaQ Trial , a prospective, multi-center, global, single arm, FDA-regulated IDE trial study to evaluate the safety and effectiveness of the MIVI Q Revascularization System for treating acute ischemic stroke. milla1cf Fri, 02/09/2024 - 09:28 February 9, 2024 — MIVI Neuroscience, Inc. mTICI 2b/3.

Stroke 105

Stroke Strokes Cerebrovascular Disease Technology 105

Cardiovascular Diabetology

MARCH 17, 2024

Hemorrhagic stroke (HS), including non-traumatic intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), constitutes a substantial proportion of cerebrovascular incidents, accounting for around 30% o.

Hemorrhage 52

Hemorrhage Stroke Strokes Research 52

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 50-58, January 1, 2024. BACKGROUND:The effect of marine omega-3 PUFAs on risk of stroke remains unclear.METHODS:We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic, and hemorrhagic) in 29 international prospective cohorts.

Stroke 74

Stroke Strokes Hemorrhage Circulation 74

Stroke Journal

FEBRUARY 1, 2024

Stroke, Ahead of Print. We sought to explore the relationship between ART and stroke risk using population-level data.Methods:We conducted a retrospective cohort study using data from the National Inpatient Sample (NIS) registry from 2015-2020, including all delivery hospitalizations for patients aged 15-55 years. 100,000 vs. 9.1/100,000),

Technology 72

Technology Hospital Stroke Strokes 72

Stroke Journal

JANUARY 26, 2024

Stroke, Ahead of Print. BACKGROUND:The dynamics of blood clot (combination of Hb [hemoglobin], fibrin, and a higher concentration of aggregated red blood cells) formation within the hematoma of an intracerebral hemorrhage is not well understood.

Hemorrhage 49

Hemorrhage Stroke Strokes Blood Clot 49

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundIntravenous thrombolysis (IVT) is an effective stroke therapy that remains underused. In this study we aim to investigate the safety and efficacy of IVT in patients with acute ischemic stroke and recent DOAC use.Methods and ResultsA systematic review and meta‐analysis of proportions evaluating IVT with recent DOAC use was conducted.

Thrombolysis 75

Thrombolysis Hemorrhage Stroke Strokes 75

DAIC

FEBRUARY 7, 2024

Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. A lot of our approaches in stroke treatment were learned from how we treat heart attacks.

Stroke 105

Stroke Strokes Outcomes Thrombolysis 105

American College of Cardiology

MAY 22, 2024

Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.

Cholesterol 75

Cholesterol Dementia Hemorrhage Cardiovascular Disease 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP164-AWP164, February 1, 2024. Introduction:Patients who have had hemorrhagic strokes experience psychological and functional deficits after hospital discharge. Conclusion:Psychological and functional outcomes for patients with hemorrhagic strokes are associated with SDoH.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Med Page Today

DECEMBER 26, 2023

(MedPage Today) -- Magnesium's hemostatic effects in intracerebral hemorrhage were supported by reduced hematoma expansion in FAST-MAG participants who achieved higher serum magnesium levels with magnesium treatment. Stroke) The American Society.

Hemorrhage 96

Hemorrhage Ablation Stroke Strokes 96

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP279-ATP279, February 1, 2024. Whether atrial cardiopathy is associated with the risk of intracranial hemorrhage in acute ischemic stroke (AIS) remains uncertain. Our primary outcomes included any intracranial hemorrhage (ICH) and symptomatic ICH (sICH) during follow-up.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

All About Cardiovascular System and Disorders

NOVEMBER 16, 2023

ECG Changes in Intracranial Hemorrhage ECG changes are fairly common in intracranial hemorrhage. Giant T inversions with QT interval prolongation may be seen in intracranial hemorrhage even without associated myocardial damage [1]. But the number of persons with lobar hemorrhage in that study was only 17%. Am Heart J.

Hemorrhage 52

Hemorrhage Myocardial Infarction Aneurysm Electrocardiogram 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP78-AWMP78, February 1, 2024. Introduction:Mobile stroke units (MSUs) are an evolving means to expedited acute stroke management. The target blood pressure goal was met much quicker in the MSU. Faster time metrics convey a hypothetical benefit towards improved patient outcomes.

Hemorrhage 40

Hemorrhage Blood Pressure Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP168-ATP168, February 1, 2024. Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. The primary outcome was coma (GCS ≤ 8) at time of admission. The median [IQR] ICH volume was 9.3

Hemorrhage 40

Hemorrhage Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP20-AWP20, February 1, 2024. Importance:Tenecteplase use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke, with results demonstrating its non-inferiority compared to alteplase. Results:Median age was 62.94 for alteplase and 64.45

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

HCPLive

FEBRUARY 2, 2024

Although a new study found antidepressants from SSRI or SNRI did not increase the risk of hemorrhagic stroke or other serious bleeding in ischemic stroke survivors, the risk increased when taking antidepressants of other classes and anti-platelet medications.

Stroke 59

Stroke Strokes Hemorrhage 59

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP81-ATMP81, February 1, 2024. Background and Purpose:Post thrombolytic intracerebral hemorrhage (ICH) is associated with higher rate of death or disability in acute ischemic stroke patients. Outcomes were determined by using utility weighted modified Rankin scale (UW-mRs) at 90-days.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

NOVEMBER 28, 2023

Stroke, Ahead of Print.

Blood Pressure 75

Blood Pressure Aneurysm Hemorrhage Stroke 75

Journal of the American Heart Association

FEBRUARY 7, 2024

Among our several subgroup analyses, we looked at difference depending on stroke status and also depending on age. Overall, we found a higher risk of hemorrhagic stroke for LDL‐C lowering, risk ratio (RR) 1.16 (95% CI, 1.01–1.32,P=0.03). Journal of the American Heart Association, Ahead of Print. 1.73) (Pint=0.14

Hemorrhage 40

Hemorrhage Stroke Strokes Cholesterol 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. Introduction:Many patients are taking antiplatelet medications when an acute stroke occurs. The exposure of interest was pre-stroke antiplatelet use categorized as none, single (SAPT), and dual antiplatelet therapy (DAPT). no antiplatelet, 36.7% SAPT, and 6.4%

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A2-A2, February 1, 2024. Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients.

Hemorrhage 40

Hemorrhage Stroke Strokes Blood Pressure 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP167-ATP167, February 1, 2024. Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] 1.10]), top-quartile hemorrhage volume (2.89 [1.08-7.75]),

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP224-ATP224, February 1, 2024. Myeloproliferative Neoplasms (MPNs) are rare acquired stem cell disorders, consisting of Essential Thrombocythemia (ET), Polycythemia Vera (PV), and Primary Myelofibrosis (PMF), complicated by thrombohemorrhagic events such as stroke.

Hemorrhage 40

Hemorrhage Stroke Strokes Heart Failure 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP84-AWMP84, February 1, 2024. Concerns have been raised regarding their potential increased risk of bleeding complications including intracerebral hemorrhage (ICH) as they are known to affect platelet function. 14.45; 52% male), among those 14% had pre-morbid AD use (age 72.13±13.23,

Hemorrhage 40

Hemorrhage Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP41-AWP41, February 1, 2024. Background:Intracerebral Hemorrhage (ICH) accounts for 10% of strokes and has higher risk for mortality and disability. Hematoma expansion may occur in ICH.

Document 40

Document Hemorrhage Stroke Strokes 40

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundAsymptomatic intracerebral hemorrhage (aICH) occurs in approximately 35% of patients with acute ischemic stroke after endovascular thrombectomy. Journal of the American Heart Association, Ahead of Print. Unlike symptomatic ICH, studies evaluating the effect of aICH on outcomes have been inconclusive.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

OCTOBER 2, 2024

Stroke, Ahead of Print. BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). Of the 1104 patients, 268 (24.3%) had AA-ICH: 148 (55.2%) with vitamin K antagonists and 107 (39.9%) with direct oral anticoagulants.

Hemorrhage 40

Hemorrhage Blood Pressure Hypertension Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP156-AWP156, February 1, 2024. Outcomes were 1) infarct growth or recurrence, and 2) increased hemorrhagic transformation (HT) in follow-up MRI compared to the initial MRI. Background:Blood viscosity (BV) affects blood vessel wall shear stress. Each patient underwent initial and follow-up MRI.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP155-ATP155, February 1, 2024. Background:Hemorrhagic transformation (HT) is a critical sequela of acute ischemic stroke (AIS). Matrix metalloproteinase-9 (MMP-9) has been implicated in the pathophysiology of hemorrhagic transformation (HT) post-acute ischemic stroke (AIS).

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. 69.88];P = 0.04), respectively.CONCLUSION“Benign” perimesencephalic subarachnoid hemorrhage pattern was associated with a ruptured aneurysm in 6.2% RESULTSEighty‐one patients were included with mean age of 55.5 ± 10.3 104];P = 0.007, OR = 22.6 [4.2–123.5];P<0.001,

Aneurysm 40

Aneurysm Hemorrhage Outcomes Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP56-ATMP56, February 1, 2024. Background:Mechanical revascularization has become an essential treatment for acute ischemic stroke patients. Post-treatment imaging frequently displays hyperdense regions, prompting concerns regarding possible cerebral hemorrhage.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40