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Stroke, Ahead of Print. Brain arteriovenous malformations (AVMs), cerebral cavernous malformations (CCMs), and intracranial aneurysms are major causes of hemorrhagicstroke, yet noninvasive therapies to prevent growth or rupture are lacking.
Katie Lin for a deep dive into why we still miss this life-threatening diagnosis, the key clinical clues, proper use of decision tools, indications for CT, indications for CTA, indications for LP and CSF interpretation for the sometimes elusive diagnosis of subarachnoid hemorrhage.
Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. vs. 0.4%) and 4X ischemic stroke rates (csHR = 4.06). year follow-up. per 100 person-year.
Stroke, Ahead of Print. The American Heart Association/American Stroke Association released a revised spontaneous intracerebral hemorrhage guideline in 2022. A working group of stroke experts reviewed this guideline and identified a subset of recommendations that were deemed suitable for creating performance measures.
Taking an anticoagulant, or blood-thinning medication, can increase one's risk of—or exacerbate—a brain bleed, also known as a brain hemorrhage, which is the deadliest type of stroke. Now, new research finds that faster treatment for these patients is associated with a greater likelihood of survival.
Stroke, Ahead of Print. After 30 years of disappointment, 2 randomized controlled trials investigating the effect of neurosurgical treatment on functional outcome in patients with intracerebral hemorrhage were published in 2024.
Stroke, Ahead of Print. BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). Of the 1104 patients, 268 (24.3%) had AA-ICH: 148 (55.2%) with vitamin K antagonists and 107 (39.9%) with direct oral anticoagulants.
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.
Heuron ICH is an advanced AI solution designed to automatically screen and signal potential cases of intracranial hemorrhage, relying solely on non-contrast CT images. Notably, Heuron ICH boasts a sensitivity of 86% and specificity of 88%, ensuring reliable and accurate assistance in critical medical scenarios.
Research Highlights: Among most ischemic (clot-caused) stroke survivors including those taking anticoagulant medications, use of antidepressants in the SSRI or SNRI class did not increase the risk of hemorrhagic (bleeds) stroke or other serious.
Stroke, Volume 56, Issue Suppl_1 , Page ADP8-ADP8, February 1, 2025. the 2023 calendar year, our comprehensive stroke metric for hemorrhagicstroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To We continue to assess compliance and project feasibility.We
Stroke, Volume 55, Issue 1 , Page 50-58, January 1, 2024. BACKGROUND:The effect of marine omega-3 PUFAs on risk of stroke remains unclear.METHODS:We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic, and hemorrhagic) in 29 international prospective cohorts.
BackgroundIntravenous thrombolysis (IVT) is an effective stroke therapy that remains underused. In this study we aim to investigate the safety and efficacy of IVT in patients with acute ischemic stroke and recent DOAC use.Methods and ResultsA systematic review and meta‐analysis of proportions evaluating IVT with recent DOAC use was conducted.
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.
Stroke, Volume 56, Issue Suppl_1 , Page A65-A65, February 1, 2025. Stroke-dizziness diagnosed in the ED is typically due to cerebellar or brainstem lesions which might only have subtle signs of central vestibular dysfunction. Stroke after the ED visit is infrequent but could have been missed at the index visit. cm (IQR, 1.1-4.0);
Stroke, Volume 56, Issue Suppl_1 , Page AWP236-AWP236, February 1, 2025. Background:A novel inflammatory score has been validated for hematoma expansion and poor outcomes in patients with intracerebral hemorrhage. Inflammatory score was significantly higher in patients with hemorrhagic transformation.
Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025. Hemorrhagicstrokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical.
Stroke, Ahead of Print. We sought to explore the relationship between ART and stroke risk using population-level data.Methods:We conducted a retrospective cohort study using data from the National Inpatient Sample (NIS) registry from 2015-2020, including all delivery hospitalizations for patients aged 15-55 years. 100,000 vs. 9.1/100,000),
Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. A lot of our approaches in stroke treatment were learned from how we treat heart attacks.
As expected, GLP-1s reduced MI risk by 9%, cardiac arrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagicstroke by 14%. Starting with the good news, GLP-1s lowered risks for 42 health outcomes while increasing risks for 19 outcomes. The less good news? Theres still no free lunch in healthcare.
Stroke, Volume 56, Issue Suppl_1 , Page ATP61-ATP61, February 1, 2025. Background:Intracerebral hemorrhage (ICH) constitutes 10% of all strokes and is the most fatal and debilitating subtype.
Stroke, Volume 56, Issue Suppl_1 , Page A125-A125, February 1, 2025. Introduction:Managing post-acute hemorrhagicstroke care is complex and necessitates close follow-up and coordination. Outcome data was similar for patients with intracerebral hemorrhage and subarachnoid hemorrhage all p<0.05.Conclusion:Prehospital
Stroke, Volume 56, Issue Suppl_1 , Page ANS7-ANS7, February 1, 2025. Background and Purpose:Intracerebral and subarachnoid hemorrhages comprise roughly 15% of all strokes but have a higher risk of mortality and morbidity than ischemic strokes.
Stroke, Volume 56, Issue Suppl_1 , Page A105-A105, February 1, 2025. Introduction:Ambient air pollution is linked to increased stroke risk, but it is unclear if associations apply to long-term exposures, equally to different stroke subtypes (ischemic versus hemorrhagic) and differ by pollutants. overall stroke: HRPM0.1=1.43,
Although a new study found antidepressants from SSRI or SNRI did not increase the risk of hemorrhagicstroke or other serious bleeding in ischemic stroke survivors, the risk increased when taking antidepressants of other classes and anti-platelet medications.
Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDIn people with suspected stroke the first assessment occurs under time pressure in the emergency department and is based solely on clinical information. Vessel occlusion was found in 227 of 410 people with ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP79-AWMP79, February 1, 2025. Background and Purpose:The inflammatory response after ischemic and hemorrhagicstroke is associated with worse clinical outcomes through immune mediated production of pro- inflammatory cytokines. Of 25 enrolled patients, mean age was 65.8 (SD,
(MedPage Today) -- Magnesium's hemostatic effects in intracerebral hemorrhage were supported by reduced hematoma expansion in FAST-MAG participants who achieved higher serum magnesium levels with magnesium treatment. Stroke) The American Society.
Stroke, Volume 56, Issue Suppl_1 , Page AWP82-AWP82, February 1, 2025. Background:ICH accounts for 10% of all strokes and is deadliest and most disabling stroke subtype. Patients with anticoagulant-related hemorrhage require rapid reversal to mitigate risk of hematoma expansion.
Stroke, Volume 56, Issue Suppl_1 , Page ATP205-ATP205, February 1, 2025. Introduction:Alzheimers Disease (AD), characterized by extracellular deposition of amyloid beta (A) plaques in brain tissue, is often comorbid with cerebral amyloid angiopathy, which carries an elevated risk of intracranial hemorrhage. andICD-10-CMcode G30.x.
Stroke, Volume 56, Issue Suppl_1 , Page ATP198-ATP198, February 1, 2025. Background:Spontaneous intracerebral hemorrhage (ICH) remains one of the most devastating forms of stroke, leaving many patients unresponsive with disorders of consciousness. years, National Institutes of Health Stroke Scale at presentation was 19.64.0,
Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The exposure was an incident diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage, subarachnoid hemorrhage, or subdural hemorrhage. 2.5), subarachnoid hemorrhage (HR, 2.0; years (IQR, 3.0-9.1),
Stroke, Volume 56, Issue Suppl_1 , Page AWMP72-AWMP72, February 1, 2025. Introduction:Emerging technologies, such as Cone-Beam CT (CBCT), may improve workflows in acute ischemic stroke (AIS). Conclusion:CBCT had high specificity for ICH and hemorrhage types.
Stroke, Volume 56, Issue Suppl_1 , Page A30-A30, February 1, 2025. Background and objective:Perfusion imaging studies consistently show a substantially increased risk of hemorrhagic transformation (HT) in severely hypoperfused tissue.
Stroke, Ahead of Print. Subarachnoid hemorrhage is a critical neurological condition accounting for about 5% of all strokes, and survivors experience long-term cognitive deterioration and increased risk of dementia.
Stroke, Ahead of Print. The exposure was a new diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and subdural hemorrhage (SDH). million patients, 14,775 had a diagnosis of intracranial hemorrhage. years (IQR, 3.0-9.1),
Stroke, Ahead of Print. BACKGROUND:Stroke-induced opposite T-cell responses in the peri-lesion area and periphery worsen stroke outcomes by aggravating brain injury or increasing infectious complications, respectively. It also reduced molecular and cellular neuroinflammation in the hemorrhagic brain early after ICH.
Stroke, Volume 56, Issue Suppl_1 , Page AWP213-AWP213, February 1, 2025. Intracerebral Hemorrhagic (ICH) stroke is the second most common type of stroke and its aftermath is often more severe than ischemia. Neural activity (Electrophysiological) data is collected pre/post stroke and during stimulation.
Stroke, Volume 56, Issue 2 , Page 527-532, February 1, 2025. BACKGROUND:Acute ischemic stroke treatment typically involves tissue-type plasminogen activator (tPA) or tenecteplase, but about 50% of patients do not achieve successful reperfusion.
Stroke, Volume 56, Issue Suppl_1 , Page ATP3-ATP3, February 1, 2025. Introduction:Thrombolysis is the gold standard of treatment for acute ischemic stroke, but it must be administered within a narrow time window. The primary outcome was symptomatic intracranial hemorrhage as defined by the ECAS III criteria.
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