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Abstract TP244: Racial and Ethnic Differences in Risk Factors and Outcomes in Young Patients With Intracerebral Hemorrhage

Stroke Journal

Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described. Less is known about disparities in risk and outcomes for young patients presenting with intracerebral hemorrhage (ICH), which is associated with higher short-term and long-term mortality.

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Abstract TMP77: Oral Health as a Risk Factor for Spontaneous Intracerebral Hemorrhage: A Mendelian Randomization Analysis

Stroke Journal

Background:Poor oral health is a highly prevalent and modifiable risk factor that is associated with higher risk of cardiovascular disease, including ischemic stroke. However, the relationship between oral health and spontaneous intracerebral hemorrhage (ICH) has not been studied.

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Voxel-Wise Map of Intracerebral Hemorrhage Locations Associated With Worse Outcomes

Stroke Journal

BACKGROUND:Prior studies on the clinical impact of intracerebral hemorrhage (ICH) location have used visual localization of hematomas to neuroanatomical structures. Stroke, Ahead of Print. However, hematomas often cross neuroanatomical structure boundaries with inter-reviewer variability in visual localization.

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Abstract TP205: Alzheimer’s Disease and Risk of Intracranial Hemorrhage

Stroke Journal

Introduction:Alzheimers Disease (AD), characterized by extracellular deposition of amyloid beta (A) plaques in brain tissue, is often comorbid with cerebral amyloid angiopathy, which carries an elevated risk of intracranial hemorrhage. This increased risk was also present for ICH, SAH, and SDH when examined separately.

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SHINE Trial Sheds Light on Deadly Stroke Complication

DAIC

The new analysis of the trial results, led by UVA Health’s Andrew Southerland , MD, found that high blood sugar shortly after thrombolysis – opening blocked arteries in the brain with a clot-busting drug – was associated with greater risk for potentially deadly brain bleeds, particularly in older patients with more severe strokes.

Stroke 105
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Abstract HUP16: Exploring Differences in Stroke Type and Stroke Risk Factors Between Young African Americans and Ghanaian Stroke Women

Stroke Journal

Non-parametric t-test and chi-square analysis was used for statistical analysis to identify significant differences between stroke type and stroke risk factors.Results:Among the 236 subjects, the median age was similar between groups (p-value 0.3940) [40 (IQR 35-43) Ghana, n= 91; 43 (IQR 34-43) in AA, n= 43, and 39 (IQR 31-43) WAA, n= 102).

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Neurovascular Decoupling Is Associated With Lobar Intracerebral Hemorrhages and White Matter Hyperintensities

Journal of the American Heart Association

ConclusionsThis raises the suggestion that a decreased neurovascular coupling in the disease process of AD is related to comorbid small vessel disease.