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Racial and ethnic disparities in riskfactors and outcomes for young patients with ischemic stroke (AIS) are well described. Less is known about disparities in risk and outcomes for young patients presenting with intracerebral hemorrhage (ICH), which is associated with higher short-term and long-term mortality.
Background:Poor oral health is a highly prevalent and modifiable riskfactor that is associated with higher risk of cardiovascular disease, including ischemic stroke. However, the relationship between oral health and spontaneous intracerebral hemorrhage (ICH) has not been studied.
BACKGROUND:Prior studies on the clinical impact of intracerebral hemorrhage (ICH) location have used visual localization of hematomas to neuroanatomical structures. Stroke, Ahead of Print. However, hematomas often cross neuroanatomical structure boundaries with inter-reviewer variability in visual localization.
Introduction:Alzheimers Disease (AD), characterized by extracellular deposition of amyloid beta (A) plaques in brain tissue, is often comorbid with cerebral amyloid angiopathy, which carries an elevated risk of intracranial hemorrhage. This increased risk was also present for ICH, SAH, and SDH when examined separately.
The new analysis of the trial results, led by UVA Health’s Andrew Southerland , MD, found that high blood sugar shortly after thrombolysis – opening blocked arteries in the brain with a clot-busting drug – was associated with greater risk for potentially deadly brain bleeds, particularly in older patients with more severe strokes.
Non-parametric t-test and chi-square analysis was used for statistical analysis to identify significant differences between stroke type and stroke risk factors.Results:Among the 236 subjects, the median age was similar between groups (p-value 0.3940) [40 (IQR 35-43) Ghana, n= 91; 43 (IQR 34-43) in AA, n= 43, and 39 (IQR 31-43) WAA, n= 102).
ConclusionsThis raises the suggestion that a decreased neurovascular coupling in the disease process of AD is related to comorbid small vessel disease.
Background:Patients with intracerebral hemorrhage (ICH) are known to have a higher risk of venous thromboembolism (VTE) than patients with acute ischemic stroke, but the factors underlying this difference have not been clearly identified. Stroke, Volume 56, Issue Suppl_1 , Page ATP201-ATP201, February 1, 2025. days (2.93).
BACKGROUND:Sex-specific differences in stroke riskfactors, clinical presentation, and outcomes are well documented. Primary end points were 90-day readmission for ischemic stroke or hemorrhage and compared between men and women. Stroke, Volume 56, Issue 2 , Page 285-293, February 1, 2025.
Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular riskfactors for ICH. After a median follow-up of 2.9 95%CI:1.002.20], Figure 1).
Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025.
CAA and ischemic and hemorrhagic stroke were identified using previously validated ICD-10 codes. Among 1,455,257 patients without prevalent stroke, including 355 of the CAA patients, there was a significant association between CAA and subsequent increased risk of any stroke (aHR, 6.3; 4.7), intracerebral hemorrhage (aHR, 32.1;
Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. Univariable analysis with chi-squared test and Mann Whitney U test followed by adjusted logistic regression were used to assess the relationship between admission factors and DoC.
Introduction:Cerebrovascular white matter disease (WMD) severity is linked to vascular riskfactors like hypertension, hyperlipidemia, and diabetes. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. Stroke, Volume 56, Issue Suppl_1 , Page ATP170-ATP170, February 1, 2025.
Introduction:Neurological complications in patients with infective endocarditis (IE), such as ischemic and hemorrhagic stroke, are well-described, serious complications of IE; however, predicting which patients are most likely to experience stroke remains uncertain. Stroke, Volume 56, Issue Suppl_1 , Page AWP279-AWP279, February 1, 2025.
Introduction:Incident intracerebral hemorrhage (ICH) is an uncommon medical event that can lead to devastating outcomes, including death. Small vessel disease (SVD), as measured by cerebral microbleeds (CMBs) and white matter hyperintensities (WMH), has been associated with riskfactors and might be a predictor of incident ICH.
cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.
Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 1.02], p<0.001), higher NIS-Subarachnoid Hemorrhage Severity Score (NIS-SSS) (12.64 [4.21-37.95], 1.02], p<0.001), higher NIS-Subarachnoid Hemorrhage Severity Score (NIS-SSS) (12.64 [4.21-37.95], A total of 61.8%
BackgroundA strong riskfactor for intracerebral hemorrhage (ICH) is elevated arterial blood pressure, which is known to vary by season, with highest values in winter months. Journal of the American Heart Association, Ahead of Print.
Endothelial damage, prothrombotic factor release, and a higher prevalence of cardiovascular riskfactors in those receiving ART have been invoked to explain this association. The study exposure was use of ART. Individual stroke subtypes (IS, SAH, ICH, and CVT) were evaluated as secondary endpoints.
Background:Anemia is a riskfactor for worse intracerebral hemorrhage (ICH) outcomes, yet the underlying drivers remain unclear. Stroke, Volume 56, Issue Suppl_1 , Page ATMP114-ATMP114, February 1, 2025. Though anemia and inflammation are interrelated, it is unknown whether anemia influences inflammatory responses to ICH.
Concerns have been raised regarding their potential increased risk of bleeding complications including intracerebral hemorrhage (ICH) as they are known to affect platelet function. These findings challenge the prevailing literature notion that AD, particularly SSRIs are linked to an increased risk of hemorrhages of all type.
Background and purpose:Brain arteriovenous malformation (bAVM) is an important riskfactor for hemorrhagic stroke in young adults, but the underlying mechanisms are unclear. Depletion of microglia reduces Col I and Col III and hemorrhage in bAVMs in mice.
Introduction:Intracerebral Hemorrhage (ICH) is a significant type of stroke, being the second most common and with a higher risk of mortality and morbidity compared to ischemic stroke. Stroke, Volume 56, Issue Suppl_1 , Page AHUP13-AHUP13, February 1, 2025.
The timing of ischemic stroke (IS) and hemorrhagic stroke (HS) in relation to MPN diagnosis among Veterans remains undefined.We This study also suggests consideration for dual antiplatelet therapy for MPNs with cardiovascular riskfactors to prevent IS and a multidisciplinary approach between neurology and hematology.
IntroductionNontraumatic Intracerebral Hemorrhage (ICH) is the second most prevalent type of stroke worldwide and is strongly linked with severe disability and mortality. Survivors of ICH have a high risk of all‐cause readmission. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.
Background:After a large intracerebral hemorrhage (ICH), the hematoma and swelling cause intracranial pressure (ICP) to increase, sometimes causing brain herniation and death. Therefore, the ICP compensation response to ICH mass effect varies across the lifespan according to riskfactors such as chronic hypertension.
IntroductionSubarachnoid Hemorrhage (SAH) is the leading cause of morbidity and mortality in stroke patients, associated with severe neurological, infectious, and thromboembolic complications. Readmitted patients both within 30 and 90 days were more likely to have a higher prevalence of vascular riskfactors and related comorbidities.
BACKGROUND:Smoking is a well-established riskfactor for subarachnoid hemorrhage (SAH), and current smokers have an increased risk of SAH. Stroke, Volume 54, Issue 12 , Page 3012-3020, December 1, 2023.
Introduction:Chronic kidney disease (CKD) is a well-established riskfactor for spontaneous intracerebral hemorrhage (ICH). Stroke, Volume 55, Issue Suppl_1 , Page AWP159-AWP159, February 1, 2024. However, the biological pathway underlying this association remains unclear.
Introduction:Prospective studies and secondary analyses from clinical trials have identified increased systolic blood pressure variability (SBPV) as a riskfactor for poor outcomes.
Background:We identified that major ABO incompatible platelet transfusions are associated with poor intracerebral hemorrhage (ICH) outcomes, yet the driver for this relationship is unknown and does not appear to be related to impaired hemostasis. Conversely, acute ICH patients are known to develop remote ischemic lesions on brain MRI.
Introduction:Pregnancy is a riskfactor for subarachnoid hemorrhage (SAH). We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).
Although MCAD can progress to MMD, the extent to which patients actually progress and the riskfactors for this progression have not been fully elucidated.Methods:We retrospectively reviewed patients with MCAD who underwentRNF213genotyping.
vs. 8.9%) hemorrhage; discharged to a skilled nursing facility (19.8% Of the 1,719 patients not LTFU, 974 (56.7%) had a provider visit, 405 (23.6%) had an unplanned admission, and 257 (14.9%) had an unplanned ED visit within 30 days post-discharge. Patients who were LTFU were significantly more likely to be male (52.9% vs. 40.7%).
Objective:This study aims to evaluate the risk of cerebrovascular events in pediatric MMD during the preoperative waiting period, and explore the related riskfactors and appropriate operation opportunities.Methods:This study is an observational cohort study, including 736 children with MMD from their initial visit until the completion of surgery.
Introduction:Stroke is a leading cause of maternal morbidity and mortality, and hemorrhagic strokes account for up to half of these cases. Patients with insufficient data for a determination were categorized as no diagnostic delay.Results:A total of 121 patients were identified, of whom 48% had hemorrhagic stroke.
Recognizing epidemiological riskfactors in local communities helps target specific populations through community education and implement appropriate healthcare delivery measures. Stroke, Volume 56, Issue Suppl_1 , Page ATP202-ATP202, February 1, 2025. Introduction:Early interventions limit morbidity and mortality in ICH patients.
Introduction:Effective care transition for ischemic or hemorrhagic stroke patients post-hospital discharge is critical. Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke riskfactors like hypertension, diabetes, and atrial fibrillation.
We have used Binary logistic regression methods to find the odd ratio for physical and emotional riskfactors for stress induced cardiomyopathy.Results:Grief disorder with an odd ratio of 7.2, Hemorrhagic stroke with an odd ratio of 1.73, ischemic stroke with an odd ratio of 1.72, depression with an odd ratio of 1.5,
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