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Genetic Insights Into Hemorrhagic Stroke and Vascular Malformations: Pathogenesis and Emerging Therapeutic Strategies

Stroke Journal

Stroke, Ahead of Print. Brain arteriovenous malformations (AVMs), cerebral cavernous malformations (CCMs), and intracranial aneurysms are major causes of hemorrhagic stroke, yet noninvasive therapies to prevent growth or rupture are lacking.

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Ep 194 Subarachnoid Hemorrhage – Recognition, Workup and Diagnosis Deep Dive

ECG Cases

Katie Lin for a deep dive into why we still miss this life-threatening diagnosis, the key clinical clues, proper use of decision tools, indications for CT, indications for CTA, indications for LP and CSF interpretation for the sometimes elusive diagnosis of subarachnoid hemorrhage.

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Abelacimab Stops Bleeding, But Stroke Impact Uncertain

CardiacWire

Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. vs. 0.4%) and 4X ischemic stroke rates (csHR = 4.06). year follow-up.

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Faster brain hemorrhage treatment increases survival odds, new study finds

Medical Xpress - Cardiology

Taking an anticoagulant, or blood-thinning medication, can increase one's risk of—or exacerbate—a brain bleed, also known as a brain hemorrhage, which is the deadliest type of stroke. Now, new research finds that faster treatment for these patients is associated with a greater likelihood of survival.

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Pathophysiology of Intracerebral Hemorrhage: Recovery Trajectories

Stroke Journal

Stroke, Ahead of Print. Recovery trajectories in intracerebral hemorrhage (ICH) are recognized as distinct from those observed in ischemic stroke.

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2 common types of antidepressants were safe for most stroke survivors

American Heart News - Stroke News

Research Highlights: Among most ischemic (clot-caused) stroke survivors including those taking anticoagulant medications, use of antidepressants in the SSRI or SNRI class did not increase the risk of hemorrhagic (bleeds) stroke or other serious.

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The Potential Risks of GLP-1s

CardiacWire

To tackle this problem, researchers compared Veterans Affairs data on 2 million T2D patients (2017-2023) taking either GLP-1s , DPP4is, SGLT2is, or usual care antihyperglycemics over a 3.68 As expected, GLP-1s reduced MI risk by 9%, cardiac arrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagic stroke by 14%.

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