Stroke Journal

FEBRUARY 27, 2024

Stroke, Ahead of Print. The primary outcome was functional status measured by the modified Rankin Scale at 90 to 180 days. Earlier SBP control was associated with better functional outcomes (modified Rankin Scale score, 3–6; odds ratio, 0.98 [95% CI, 0.97–0.99]) SD, 13.0], 2120 [36.8%] females) were included in analyses.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP78-AWMP78, February 1, 2024. Introduction:Mobile stroke units (MSUs) are an evolving means to expedited acute stroke management. Faster time metrics convey a hypothetical benefit towards improved patient outcomes. The target blood pressure goal was met much quicker in the MSU.

Hemorrhage 40

Hemorrhage Blood Pressure Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP81-AWMP81, February 1, 2024. Introduction:Intracerebral Hemorrhage (ICH) leads to high rates of morbidity and mortality. Malnutrition is common in stroke patients and leads to worse outcomes. 7.34) and lobar (OR 3.15, 95% CI 1.67-5.94) 5.94) groups. Albumin (OR 2.27, 95% CI 1.05-4.90)

Hemorrhage 40

Hemorrhage BMI Outcomes Coronary Artery Disease 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP168-ATP168, February 1, 2024. Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. The primary outcome was coma (GCS ≤ 8) at time of admission. The median [IQR] ICH volume was 9.3

Hemorrhage 40

Hemorrhage Stroke Strokes Risk Factors 40

Journal of the American Heart Association

JANUARY 31, 2024

BackgroundPatients with ischemic stroke and concomitant COVID‐19 infection have worse outcomes than those without this infection, but the impact of COVID‐19 on hemorrhagic stroke remains unclear. We aimed to assess if COVID‐19 worsens outcomes in intracerebral hemorrhage (ICH).Methods

COVID-19 40

COVID-19 Hemorrhage Outcomes Nursing 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP19-ATP19, February 1, 2024. Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 1.02], p<0.001), higher NIS-Subarachnoid Hemorrhage Severity Score (NIS-SSS) (12.64 [4.21-37.95], The median age was 11.8 years (95% CI, 11.0-12.5),

Pediatrics 40

Pediatrics Hemorrhage Outcomes Hospital 40

DAIC

FEBRUARY 7, 2024

Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. The study was looking for improvement in functional outcomes at 90 days. 9 Phoenix, AZ.

Stroke 105

Stroke Strokes Outcomes Thrombolysis 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP34-ATP34, February 1, 2024. Comparative outcome analyses between pre-COVID (2016-2019) and COVID year (2020) were performed. Background:Hemorrhagic cerebrovascular manifestations are known to be associated with COVID-19. years with 72,650 (61.0%) being female.

COVID-19 40

COVID-19 Hemorrhage Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A2-A2, February 1, 2024. Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients. Higher mortality was noted after 5 days post-ictus in the MSU group (26.5% vs. 14.1%, p = 0.04).Conclusion:In

Hemorrhage 40

Hemorrhage Stroke Strokes Blood Pressure 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP177-AWP177, February 1, 2024. Clinical characteristics, technical considerations associated with thrombectomy, severity and subtypes of HT (Heidelberg) and clinical outcomes were analyzed.Results:HT was adjudicated present in 70 out of 149 (47.0%) consecutive thrombectomy patients.

Hemorrhage 40

Hemorrhage Outcomes Thrombolysis Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. Introduction:Many patients are taking antiplatelet medications when an acute stroke occurs. The exposure of interest was pre-stroke antiplatelet use categorized as none, single (SAPT), and dual antiplatelet therapy (DAPT). no antiplatelet, 36.7% SAPT, and 6.4%

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Journal of the American Heart Association

FEBRUARY 7, 2024

Among our several subgroup analyses, we looked at difference depending on stroke status and also depending on age. Overall, we found a higher risk of hemorrhagic stroke for LDL‐C lowering, risk ratio (RR) 1.16 (95% CI, 1.01–1.32,P=0.03). Journal of the American Heart Association, Ahead of Print. 1.73) (Pint=0.14

Hemorrhage 40

Hemorrhage Stroke Strokes Cholesterol 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP244-ATP244, February 1, 2024. Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described. All tests were two-tailed and the error rate was set at 5%.Results:Among Results:Among 430 patients who met inclusion criteria, 22.3%

Risk Factors 40

Risk Factors Hemorrhage Outcomes Inpatient 40

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundAsymptomatic intracerebral hemorrhage (aICH) occurs in approximately 35% of patients with acute ischemic stroke after endovascular thrombectomy. Unlike symptomatic ICH, studies evaluating the effect of aICH on outcomes have been inconclusive. Journal of the American Heart Association, Ahead of Print.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP76-ATMP76, February 1, 2024. Introduction:Intraventricular hemorrhage (IVH), a common complication of intracerebral hemorrhage (ICH), can occur with little or no associated ICH (mostly IVH, mIVH). mIVH is reported to have better outcomes than IVH associated with substantial ICH.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe use of detachable coils for endovascular embolization of cerebral aneurysms has become a safe and effective alternative to direct surgical clipping in patients with ruptured aneurysmal subarachnoid hemorrhage.

Aneurysm 40

Aneurysm Stents Stent Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP167-ATP167, February 1, 2024. Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] Hispanic, 8.5% Asian, and 1.6%

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. 69.88];P = 0.04), respectively.CONCLUSION“Benign” perimesencephalic subarachnoid hemorrhage pattern was associated with a ruptured aneurysm in 6.2% Underlying aneurysm, symptomatic vasospasm, and hydrocephalus were associated with lower rates of good clinical outcome.

Aneurysm 40

Aneurysm Hemorrhage Outcomes Hospital 40

ADN Center of Excellence

OCTOBER 28, 2024

On October 29th, the global community observes World Stroke Day , an occasion dedicated to raising awareness about one of the most formidable threats to global health: stroke. Often called the "silent killer," stroke is a leading cause of death and disability worldwide.

Stroke 59

Stroke Strokes Education Innovation 59

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP74-AWMP74, February 1, 2024. Purpose:We previously reported that activated T cells accumulate in the perihematomal regions after Intracerebral hemorrhage (ICH) and aggravate hemorrhagic brain injury.

Hemorrhage 40

Hemorrhage Outcomes Pharmacology Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP75-AWMP75, February 1, 2024. Background:Injury location is an established outcome predictor in intracerebral hemorrhage (ICH), with most studies focusing on outcomes relating to motor deficits. In short, type VII collagenase was injected into the left or right striatum (0.0

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionImportance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA).

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP31-AWP31, February 1, 2024. Background:Tenecteplase (TNK) has been reported to be non-inferior to alteplase from a clinical outcome and safety standpoint according to recent studies. Symptomatic intracranial hemorrhage(sICH) was higher inTNK group (8.3% versus3.3%, p=0.075).

Stroke 40

Stroke Strokes Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP166-AWP166, February 1, 2024. Background:Early initiation of antidepressants (ADs) are associated with improved functional recovery, but are associated with an increased risk of major bleeds among hemorrhagic stroke (HS) patients. Mirtazapine, bupropion, trazodone, or tricyclic ADs).

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 22-30, January 1, 2024. BACKGROUND:Cerebral cavernous malformation with symptomatic hemorrhage (SH) are targets for novel therapies. had at least one abnormal patient-reported outcome-measurement information system, Version 2.0 SH and asymptomatic change rates were adjudicated.

Hemorrhage 40

Hemorrhage Outcomes Quality of Life Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntravenous thrombolytics (IVT) and mechanical thrombectomy (MT) have become the standards of care for treating patients with large vessel occlusion (LVO) acute ischemic strokes (AIS) [1‐4}. in a large multicentered meta‐analysis [2,6].

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP41-AWP41, February 1, 2024. Background:Intracerebral Hemorrhage (ICH) accounts for 10% of strokes and has higher risk for mortality and disability. Future considerations are to examine if adverse outcomes exist due to documentation and treatment gaps.

Document 40

Document Hemorrhage Stroke Strokes 40

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundIntravenous thrombolysis (IVT) is an effective stroke therapy that remains underused. In this study we aim to investigate the safety and efficacy of IVT in patients with acute ischemic stroke and recent DOAC use.Methods and ResultsA systematic review and meta‐analysis of proportions evaluating IVT with recent DOAC use was conducted.

Thrombolysis 75

Thrombolysis Stroke Strokes Hemorrhage 75

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundThe impact of atrial fibrillation (AF) on the clinical outcomes in patients with acute ischemic stroke (AIS) who received endovascular thrombectomy remains unclear. Data were meta‐analyzed to compare the outcomes among patients with AIS with and without AF who received endovascular thrombectomy. 1.08]; [95% PI, 0.77–1.11]),

Atrial Fibrillation 45

Atrial Fibrillation Outcomes Hemorrhage Stroke 45

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP113-ATP113, February 1, 2024. Introduction:Screening for dysphagia is vital in post-stroke care, with the Yale Swallow Protocol being a widely recognized tool. The primary outcome was the rate of passing the Yale Swallow Protocol screening, with data stratified by race.

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP158-ATP158, February 1, 2024. Introduction:Viscoelastic hemostatic assays can detect coagulopathy relevant for intracerebral hemorrhage (ICH) patients at risk for hematoma expansion. However, it is unclear whether these assays associate with long term ICH outcomes.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP209-AWP209, February 1, 2024. Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described.

Hemorrhage 40

Hemorrhage Outcomes Cardiovascular Disease Stroke 40

DAIC

FEBRUARY 8, 2024

Image courtesy: Getty Images christine.book Thu, 02/08/2024 - 15:53 February 8, 2024 — The latest late-breaking science from the second day of the American Stroke Association ’s International Stroke Conference , ISC 2024 , shed light on the use of artificial intelligence ( AI ) to help guide treatment decisions for stroke patients.

Stroke 105

Stroke Strokes Research Heart Attack 105

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 50-58, January 1, 2024. BACKGROUND:The effect of marine omega-3 PUFAs on risk of stroke remains unclear.METHODS:We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic, and hemorrhagic) in 29 international prospective cohorts.

Stroke 74

Stroke Strokes Hemorrhage Circulation 74

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP156-AWP156, February 1, 2024. Outcomes were 1) infarct growth or recurrence, and 2) increased hemorrhagic transformation (HT) in follow-up MRI compared to the initial MRI. Background:Blood viscosity (BV) affects blood vessel wall shear stress. 1.27] vs. 0.72 [0.59-0.81], 0.81], P=0.25

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP155-ATP155, February 1, 2024. Background:Hemorrhagic transformation (HT) is a critical sequela of acute ischemic stroke (AIS). Matrix metalloproteinase-9 (MMP-9) has been implicated in the pathophysiology of hemorrhagic transformation (HT) post-acute ischemic stroke (AIS).

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP139-AWP139, February 1, 2024. Background:Cerebral vasospasm is a well-known complication after aneurysmal subarachnoid hemorrhage (aSAH) and occurs more commonly in younger patients. Worse outcome was defined as 3-month modified Rankin Scale 4-6.

Atherosclerosis 40

Atherosclerosis Aneurysm Hemorrhage Outcomes 40