Journal of the American Heart Association

JANUARY 31, 2024

BackgroundPatients with ischemic stroke and concomitant COVID‐19 infection have worse outcomes than those without this infection, but the impact of COVID‐19 on hemorrhagic stroke remains unclear. We aimed to assess if COVID‐19 worsens outcomes in intracerebral hemorrhage (ICH).Methods

COVID-19 40

COVID-19 Hemorrhage Outcomes Nursing 40

DAIC

FEBRUARY 7, 2024

Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. The study was looking for improvement in functional outcomes at 90 days. 9 Phoenix, AZ.

Stroke 105

Stroke Strokes Outcomes Thrombolysis 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP19-ATP19, February 1, 2024. Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 1.02], p<0.001), higher NIS-Subarachnoid Hemorrhage Severity Score (NIS-SSS) (12.64 [4.21-37.95], The median age was 11.8 years (95% CI, 11.0-12.5),

Pediatrics 40

Pediatrics Hemorrhage Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP34-ATP34, February 1, 2024. Comparative outcome analyses between pre-COVID (2016-2019) and COVID year (2020) were performed. Background:Hemorrhagic cerebrovascular manifestations are known to be associated with COVID-19. years with 72,650 (61.0%) being female.

COVID-19 40

COVID-19 Hemorrhage Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A2-A2, February 1, 2024. Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients. Higher mortality was noted after 5 days post-ictus in the MSU group (26.5% vs. 14.1%, p = 0.04).Conclusion:In

Hemorrhage 40

Hemorrhage Stroke Strokes Blood Pressure 40

Journal of the American Heart Association

FEBRUARY 7, 2024

Among our several subgroup analyses, we looked at difference depending on stroke status and also depending on age. Overall, we found a higher risk of hemorrhagic stroke for LDL‐C lowering, risk ratio (RR) 1.16 (95% CI, 1.01–1.32,P=0.03). Journal of the American Heart Association, Ahead of Print. 1.73) (Pint=0.14

Hemorrhage 40

Hemorrhage Stroke Strokes Cholesterol 40

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundAsymptomatic intracerebral hemorrhage (aICH) occurs in approximately 35% of patients with acute ischemic stroke after endovascular thrombectomy. Unlike symptomatic ICH, studies evaluating the effect of aICH on outcomes have been inconclusive. Journal of the American Heart Association, Ahead of Print.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP76-ATMP76, February 1, 2024. Introduction:Intraventricular hemorrhage (IVH), a common complication of intracerebral hemorrhage (ICH), can occur with little or no associated ICH (mostly IVH, mIVH). mIVH is reported to have better outcomes than IVH associated with substantial ICH.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe use of detachable coils for endovascular embolization of cerebral aneurysms has become a safe and effective alternative to direct surgical clipping in patients with ruptured aneurysmal subarachnoid hemorrhage.

Aneurysm 40

Aneurysm Stents Stent Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP167-ATP167, February 1, 2024. Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] Hispanic, 8.5% Asian, and 1.6%

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. 69.88];P = 0.04), respectively.CONCLUSION“Benign” perimesencephalic subarachnoid hemorrhage pattern was associated with a ruptured aneurysm in 6.2% Underlying aneurysm, symptomatic vasospasm, and hydrocephalus were associated with lower rates of good clinical outcome.

Aneurysm 40

Aneurysm Hemorrhage Outcomes Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP75-AWMP75, February 1, 2024. Background:Injury location is an established outcome predictor in intracerebral hemorrhage (ICH), with most studies focusing on outcomes relating to motor deficits. In short, type VII collagenase was injected into the left or right striatum (0.0

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP31-AWP31, February 1, 2024. Background:Tenecteplase (TNK) has been reported to be non-inferior to alteplase from a clinical outcome and safety standpoint according to recent studies. Symptomatic intracranial hemorrhage(sICH) was higher inTNK group (8.3% versus3.3%, p=0.075).

Stroke 40

Stroke Strokes Hemorrhage Outcomes 40

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 22-30, January 1, 2024. BACKGROUND:Cerebral cavernous malformation with symptomatic hemorrhage (SH) are targets for novel therapies. had at least one abnormal patient-reported outcome-measurement information system, Version 2.0 SH and asymptomatic change rates were adjudicated.

Hemorrhage 40

Hemorrhage Outcomes Quality of Life Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP166-AWP166, February 1, 2024. Background:Early initiation of antidepressants (ADs) are associated with improved functional recovery, but are associated with an increased risk of major bleeds among hemorrhagic stroke (HS) patients. Mirtazapine, bupropion, trazodone, or tricyclic ADs).

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionImportance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA).

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP41-AWP41, February 1, 2024. Background:Intracerebral Hemorrhage (ICH) accounts for 10% of strokes and has higher risk for mortality and disability. Future considerations are to examine if adverse outcomes exist due to documentation and treatment gaps.

Document 40

Document Hemorrhage Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP209-AWP209, February 1, 2024. Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described.

Hemorrhage 40

Hemorrhage Outcomes Cardiovascular Disease Hypertension 40

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundThe impact of atrial fibrillation (AF) on the clinical outcomes in patients with acute ischemic stroke (AIS) who received endovascular thrombectomy remains unclear. Data were meta‐analyzed to compare the outcomes among patients with AIS with and without AF who received endovascular thrombectomy. 1.08]; [95% PI, 0.77–1.11]),

Atrial Fibrillation 45

Atrial Fibrillation Outcomes Hemorrhage Stroke 45

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundIntravenous thrombolysis (IVT) is an effective stroke therapy that remains underused. In this study we aim to investigate the safety and efficacy of IVT in patients with acute ischemic stroke and recent DOAC use.Methods and ResultsA systematic review and meta‐analysis of proportions evaluating IVT with recent DOAC use was conducted.

Thrombolysis 75

Thrombolysis Hemorrhage Stroke Strokes 75

DAIC

FEBRUARY 8, 2024

Image courtesy: Getty Images christine.book Thu, 02/08/2024 - 15:53 February 8, 2024 — The latest late-breaking science from the second day of the American Stroke Association ’s International Stroke Conference , ISC 2024 , shed light on the use of artificial intelligence ( AI ) to help guide treatment decisions for stroke patients.

Research 105

Research Stroke Strokes Heart Attack 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP139-AWP139, February 1, 2024. Background:Cerebral vasospasm is a well-known complication after aneurysmal subarachnoid hemorrhage (aSAH) and occurs more commonly in younger patients. Worse outcome was defined as 3-month modified Rankin Scale 4-6.

Atherosclerosis 40

Atherosclerosis Aneurysm Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP156-AWP156, February 1, 2024. Outcomes were 1) infarct growth or recurrence, and 2) increased hemorrhagic transformation (HT) in follow-up MRI compared to the initial MRI. Background:Blood viscosity (BV) affects blood vessel wall shear stress. 1.27] vs. 0.72 [0.59-0.81], 0.81], P=0.25

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 50-58, January 1, 2024. BACKGROUND:The effect of marine omega-3 PUFAs on risk of stroke remains unclear.METHODS:We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic, and hemorrhagic) in 29 international prospective cohorts.

Stroke 74

Stroke Strokes Hemorrhage Circulation 74

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundInformation on the long‐term prognosis in patients with isolated thalamic stroke is sparse. The Functional Independence Measure and modified Rankin Scale were used to assess functional outcomes. A total of 297 patients were included, consisting of 235 with ischemic and 62 with hemorrhagic stroke.

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP155-ATP155, February 1, 2024. Background:Hemorrhagic transformation (HT) is a critical sequela of acute ischemic stroke (AIS). Matrix metalloproteinase-9 (MMP-9) has been implicated in the pathophysiology of hemorrhagic transformation (HT) post-acute ischemic stroke (AIS).

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP175-AWP175, February 1, 2024. Current guidelines for blood pressure (BP) management in patients with intracerebral hemorrhage (ICH) recommend acute lowering of systolic BP (SBP) to 140 mm Hg with a maintenance goal of 130 - 150 mm Hg. All ICH patients from 2018 through 2022 were included.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP80-AWMP80, February 1, 2024. Introduction:Pregnant patients are at risk of neurological complications including intracerebral hemorrhage (ICH). Pregnant patients experienced lower in-hospital mortality (12.4% vs 23.2%, p<0.001).

Hemorrhage 40

Hemorrhage Outcomes Kidney Disease Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP56-ATMP56, February 1, 2024. Background:Mechanical revascularization has become an essential treatment for acute ischemic stroke patients. Post-treatment imaging frequently displays hyperdense regions, prompting concerns regarding possible cerebral hemorrhage.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 78-88, January 1, 2024. BACKGROUND:The association of COVID-19 with higher bleeding risk and worse outcomes in acute ischemic stroke (AIS) undergoing revascularization may be related to the presence of infection symptoms. 1.99]; aOR, 1.63 [95% CI, 1.14–2.32], 2.32], respectively). versus 85.6%;P<0.001),

COVID-19 40

COVID-19 Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Both anticoagulants can be used intraoperatively and postoperatively for DVT prophylaxis in patients undergoing subarachnoid hemorrhage (SAH) treatment. SAH severity was determined using the National Institute of Health Stroke Scale as a template.

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Thrombosis 40

Stroke Journal

MARCH 21, 2024

Stroke, Ahead of Print. BACKGROUND:Patient-reported outcome measures (PROMs) describe health status from the perspective of the patient. There is growing interest in incorporating PROMs into clinical trials, but the extent that such measures are used in contemporary stroke trials is uncertain.

Stroke 40

Stroke Strokes Outcomes Quality of Life 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP77-AWP77, February 1, 2024. Purpose:The quality of acute stroke care can be improved through the nationwide compulsory quality assessment. Acute stroke quality assessment (ASQA) covers most acute stroke patients treated in acute care hospitals in Korea.

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP5-AWP5, February 1, 2024. Background:Diabetes mellitus (DM) is one of the risk factors for acute ischemic stroke, usually leading to poor prognosis. While DM can reduce the effect of intravenous thrombolysis, metformin can have a positive outcome on AIS patients.

Diabetes 40

Diabetes Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP219-ATP219, February 1, 2024. Introduction:The outcomes of mechanical thrombectomy (MT) for patients with acute ischemic stroke (AIS) caused by medium vessel occlusions (MeVOs) in different vessels remains unknown. years and 49 patients were female (46.7%). 95% confidence interval 1.71-62.2,

Outcomes 40

Outcomes Stroke Strokes Aneurysm 40

Hypertension Journal

JANUARY 2, 2024

BACKGROUND:Data on systolic blood pressure (SBP) trajectories in the first 24 hours after endovascular thrombectomy (EVT) in acute ischemic stroke are limited. 2.82]), intracranial hemorrhage (aOR, 1.84 [95% CI, 1.31–2.59]), 2.31]), and worse functional outcomes (adjusted common odds ratio,1.92 [95% CI, 1.47–2.50]).CONCLUSIONS:Patients

Blood Pressure 40

Blood Pressure Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP164-ATP164, February 1, 2024. Background:Hyponatremia is the most common electrolyte abnormality seen in intracerebral hemorrhage (ICH) and is associated with a nearly doubled mortality rate and more severe presentations. Minimum Na reliably predicted death in this model (β=0.007, p=0.023).Conclusions:Several

Hemorrhage 40

Hemorrhage Inpatient Outcomes Diabetes 40