Stroke Journal

JANUARY 30, 2025

Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH.

Atrial Fibrillation 40

Atrial Fibrillation Hemorrhage Risk Factors Kidney Disease 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Pregnancy is a risk factor for subarachnoid hemorrhage (SAH). We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).

Inpatient 40

Inpatient Aneurysm Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Background:Anemia is a risk factor for worse intracerebral hemorrhage (ICH) outcomes, yet the underlying drivers remain unclear. Further work is required to assess whether anemia modification can abrogate pathologic immune pathways and improve ICH outcomes.

Hemorrhage 40

Hemorrhage Diet Risk Factors Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Excessive sodium intake is the top dietary risk factor for mortality and non-communicable diseases such as stroke. Lack of NR4a1 in MDMs recapitulated HSD-induced negative impacts on ICH outcomes.

Hemorrhage 40

Hemorrhage Transplant Diet Stroke 40

Circulation

NOVEMBER 11, 2024

The primary outcome was a composite of the incidence of myocardial infarction and ischemic and hemorrhagic stroke, obtained by tracking the medical use data of the first-ever ICD-10 codes. HTN elevated the incidence risk of major cardiovascular disease by 2.16 years and median follow-up duration was 15.9

Myocardial Infarction 40

Myocardial Infarction Hypertension Cardiovascular Disease Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Background:We identified that major ABO incompatible platelet transfusions are associated with poor intracerebral hemorrhage (ICH) outcomes, yet the driver for this relationship is unknown and does not appear to be related to impaired hemostasis. Conversely, acute ICH patients are known to develop remote ischemic lesions on brain MRI.

Hemorrhage 40

Hemorrhage Ischemia Risk Factors Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. or greater. vs. 20.5%; p = 0.048) and stenting (28.4%

Outcomes 40

Outcomes Angioplasty Atrial Fibrillation Diabetes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Diabetes mellitus (DM) is one of the risk factors for acute ischemic stroke, usually leading to poor prognosis. While DM can reduce the effect of intravenous thrombolysis, metformin can have a positive outcome on AIS patients. The outcomes of stroke in diabetic patients receiving metformin is largely unexplored.

Diabetes 40

Diabetes Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Our primary outcome was post-discharge LTFU, defined as having zero post-discharge encounters within 12 months. Our secondary outcomes included having one or more outpatient visits with a provider, unplanned hospitalizations, and emergency department (ED) visits within 30 days post-discharge. vs. 47.4%); have an intracerebral (12.1%

Academic 40

Academic Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:White matter hyperintensities (WMH) are associated with worse clinical outcomes after stroke. Using logistic regression, we tested the associations between WMH fraction, presence and severity of HARM, and clinical outcomes. WMH fraction was associated with a higher risk of severe HARM (OR: 1.35, 95% CI: 1.03-1.78)

Stroke 40

Stroke Strokes Outcomes Risk Factors 40

Stroke Journal

JANUARY 30, 2025

The primary outcome was 3-month functional outcome by modified Rankin scale (mRS). Patients with elevated traditional risk factors at admission may benefit more from thrombolytic therapy compared to those with high inflammatory response indicators. Stroke, Volume 56, Issue Suppl_1 , Page ATP20-ATP20, February 1, 2025.

Thrombolysis 40

Thrombolysis Stroke Strokes Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Recognizing epidemiological risk factors in local communities helps target specific populations through community education and implement appropriate healthcare delivery measures. ICH score estimated disease severity and modified Rankin score (mRS) at discharge defined patient outcome. Comparison between race/ethnicity [i.e.,

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

It represents a high mortality and morbidity rate due to its risk of rupture causing Sub Arachnoid Hemorrhage which is a dangerous and life‐threatening condition. Based on limited reports, the 30‐day mortality rate from aneurysmal Sub Arachnoid Hemorrhage was 26.6% Africa presents a fatality rate higher than developed countries.

Aneurysm 40

Aneurysm Hemorrhage Risk Factors Outcomes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Effective care transition for ischemic or hemorrhagic stroke patients post-hospital discharge is critical. Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke risk factors like hypertension, diabetes, and atrial fibrillation.

Stroke 40

Stroke Strokes Risk Factors Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

As the eligibility criteria for MT ease, more patients will undergo the procedure who have risk factors for complications such as malignant edema or hemorrhagic conversion that require decompressive craniectomy (DC).

Stroke 40

Stroke Strokes Outcomes Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Although prior antiplatelet therapy (APT) could potentially contribute to bleeding risk, the influence of prior APT on intravenous thrombolysis outcomes remains controversial. A favorable outcome was defined as a modified Rankin Scale of 0 to 1 at 90-days.

Stroke 40

Stroke Strokes Thrombolysis Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Head CT hyperdensity (HCH) commonly follows mechanical thrombectomy (MT) for large vessel occlusion (LVO), often due to contrast extravasation (CE) or intracerebral hemorrhage (ICH). Given the 20-88% prevalence in studies, understanding associated variables is crucial for outcomes.

Stroke 40

Stroke Strokes Risk Factors Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Endothelial damage, prothrombotic factor release, and a higher prevalence of cardiovascular risk factors in those receiving ART have been invoked to explain this association. We included all delivery hospitalizations for female patients aged 15-55 years. The study exposure was use of ART.

Technology 40

Technology Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

We sought to establish predictive factors for delayed seizures to stratify risk and guide clinical management.Methods:We analyzed data from the Direct Oral Anticoagulants Versus Warfarin in the Treatment of Cerebral Venous Thrombosis (ACTION-CVT) study of consecutive patients with CVT from 2015 - 2020. p=0.196), alcohol abuse (OR 3.88

Thrombosis 40

Thrombosis Risk Factors Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionA high level of low‐density lipoprotein ‐ cholesterol (LDL‐C) is a known risk factor for ischemic stroke1. However, the impact of LDL‐C on stroke outcomes after mechanical thrombectomy (MT) is unclear. In this study, we aim to examine the relationship between LDL‐C level and post‐MT functional outcome.

Thrombolysis 40

Thrombolysis Outcomes Cholesterol Risk Factors 40

Stroke Journal

FEBRUARY 10, 2025

The primary end point was a composite of adverse neurovascular events (multiple vessel cervical artery dissection, ischemic stroke, intracerebral hemorrhage, and any neurovascular intervention) at 5- and 10-year follow-ups. Independent risk factors were identified using univariate and multivariate logistic regression analyses.

Risk Factors 40

Risk Factors Hemorrhage Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Significant heterogeneity was noted in the outcome (I2 = 82%). 1.09; I2 = 67%; p = 0.08) for hemorrhagic stroke while a pooled aHR = 0.98; 95% CI: 0.89-1.20; 1.20; I2 = 0%; p = 0.66) for ischemic stroke.Conclusion:Our analysis reveals an elevated stroke risk post-hysterectomy. 1.40; p &lt 0.01).

Stroke 40

Stroke Strokes Risk Factors Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Background:Hyperperfusion phenomenon (HPP) constitutes a significant risk factor for adverse outcomes following carotid artery stenting (CAS). Currently, the sole method for evaluating the risk of HPP post-CAS is the invasive acetazolamide (ACZ) challenge test.

Stents 40

Stents Stent Stenosis Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

We retrospectively reviewed these patient charts for demographic variables, and clinical and radiographic outcomes. Results:There were no significant differences in baseline demographic variables including age, gender, presenting NIHSS, and vascular risk factors between the de novo and rescue groups. X2(1,N=84) = 6.1,

Risk Factors 40

Risk Factors Hemorrhage Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The underlying etiology and risk factors remain unclear due to the limited number of reported cases and the incomplete understanding of the underlying mechanisms. Intra‐arterial and intrathecal vasodilators have been reportedly used with variable outcomes.

Thrombosis 40

Thrombosis Risk Factors Hemorrhage Research 40

Journal of the American Heart Association

JANUARY 31, 2024

1.145];P=0.002; area under the curve [AUC], 0.833) and PIC (aOR, 1.337 [95% CI, 1.087–1.644];P=0.006; AUC, 0.771) correlated significantly with higher symptomatic intracranial hemorrhage risk. Each 1‐unit increase in ischemic TAT (adjusted odds ratio [aOR], 1.086 [95% CI, 1.03–1.145];P=0.002;

Stroke 40

Stroke Strokes Risk Factors Hemorrhage 40

Stroke Journal

JANUARY 26, 2025

BACKGROUND:Sex-specific differences in stroke risk factors, clinical presentation, and outcomes are well documented. Primary end points were 90-day readmission for ischemic stroke or hemorrhage and compared between men and women. Stroke, Volume 56, Issue 2 , Page 285-293, February 1, 2025.

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Journal of the American Heart Association

APRIL 7, 2025

BackgroundNontraumatic subarachnoid hemorrhage (SAH) presents a significant health burden, yet the influence of social determinants of health on outcomes remains unclear. Outcomes included inhospital death, length of stay, and discharge disposition (good: home/rehabilitation; poor: longterm facility/hospice/death).

Hemorrhage 40

Hemorrhage Outcomes Risk Factors Strokes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Education, a key modifiable social determinant of health, plays a significant role in shaping outcomes related to ischemic stroke. Higher educational attainment has been linked to improved management of risk factors and greater adherence to medical treatments. See Table 1 for demographics by education group.

Education 40

Education Hemorrhage Outcomes Blood Pressure 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:While the attention on racial, ethnic, and gender differences in ischemic stroke has progressed beyond reporting to evaluating corrective activities, less is known about disparities in hemorrhagic stroke evaluation and care, especially amongst young population. Conclusion:Men had a higher risk of ICH than women.

Risk Factors 40

Risk Factors Hemorrhage Outcomes Blood Pressure 40

Stroke Journal

JANUARY 30, 2025

Introduction:Chronic kidney disease (CKD) is a risk factor for intracerebral hemorrhage (ICH) and for worse outcomes following ICH. Univariate analysis for QSM/CMB risk factors was assessed using Pearson correlation and t-test, while multivariate analysis was assessed using linear regression.

Kidney Disease 40

Kidney Disease Hemorrhage Risk Factors Heart Disease 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Incident intracerebral hemorrhage (ICH) is an uncommon medical event that can lead to devastating outcomes, including death. Small vessel disease (SVD), as measured by cerebral microbleeds (CMBs) and white matter hyperintensities (WMH), has been associated with risk factors and might be a predictor of incident ICH.

Hemorrhage 40

Hemorrhage Risk Factors Hypertension Atherosclerosis 40

Stroke Journal

JANUARY 30, 2025

Background:Spontaneous intracerebral hemorrhage (sICH) is a neurological condition characterized by the rupture of blood vessels within the brain, resulting in the formation of a hematoma and subsequent brain injury. Tobacco use is also correlated with worsened outcomes following sICH.

Hemorrhage 40

Hemorrhage Outcomes Risk Factors Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Intracerebral hemorrhage (ICH) has high morbidity and mortality without available targets for intervention. No studies have evaluated polyamines as they relate to ICH occurrence or outcomes.

Hemorrhage 40

Hemorrhage Risk Factors Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Prospective studies and secondary analyses from clinical trials have identified increased systolic blood pressure variability (SBPV) as a risk factor for poor outcomes. The primary outcome was severe disability or death (SDD; modified Rankin Scale ≥4) at 90-days after discharge.

Blood Pressure 40

Blood Pressure Hemorrhage Hospital Outcomes 40

Stroke Journal

JANUARY 30, 2025

We aimed to determine the prevalence of acute ischemic stroke (AIS) and intracranial hemorrhage (ICH) in patients with ITP and iTTP in a systematic review and meta-analysis.Methods:We used PubMed, Embase, Cochrane, Web of Science, and Scopus using text related to ITP, iTTP, stroke, AIS, and ICH from inception to 11/3/2023.

Hemorrhage 40

Hemorrhage Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Chronic kidney disease (CKD) is a risk factor for intracerebral hemorrhage (ICH) and for worse outcomes following ICH. In this study, we examined the relationship between ICH and CKD, as well as intracranial arterial calcification (IAC) as an intermediate biomarker.

Kidney Disease 40

Kidney Disease Hemorrhage Risk Factors Biomarkers 40