Journal of the American Heart Association

JANUARY 31, 2024

BackgroundPatients with ischemic stroke and concomitant COVID‐19 infection have worse outcomes than those without this infection, but the impact of COVID‐19 on hemorrhagic stroke remains unclear. We aimed to assess if COVID‐19 worsens outcomes in intracerebral hemorrhage (ICH).Methods

COVID-19 40

COVID-19 Hemorrhage Outcomes Nursing 40

Stroke Journal

FEBRUARY 1, 2024

Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 1.02], p<0.001), higher NIS-Subarachnoid Hemorrhage Severity Score (NIS-SSS) (12.64 [4.21-37.95], Stroke, Volume 55, Issue Suppl_1 , Page ATP19-ATP19, February 1, 2024. 37.95], p<0.001), coagulopathy (5.72, [1.40-23.29],

Pediatrics 40

Pediatrics Hemorrhage Outcomes Inpatient 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe use of detachable coils for endovascular embolization of cerebral aneurysms has become a safe and effective alternative to direct surgical clipping in patients with ruptured aneurysmal subarachnoid hemorrhage. In order to avoid thromboembolic complications in these cases, patients require treatment with antiplatelet therapy.

Aneurysm 40

Aneurysm Stents Stent Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Intraventricular hemorrhage (IVH), a common complication of intracerebral hemorrhage (ICH), can occur with little or no associated ICH (mostly IVH, mIVH). mIVH is reported to have better outcomes than IVH associated with substantial ICH. Age and IVH volume were final model independent predictors of good outcome.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] 1.10]), top-quartile hemorrhage volume (2.89 [1.08-7.75]), female) with an ethno-racial distribution of 57.6%

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

BACKGROUNDThe rate of underlying ruptured aneurysms, complications, and their relevance to outcomes in “benign” perimesencephalic subarachnoid hemorrhage are not well known and underreported.METHODSRetrospective analysis of patients with perimesencephalic subarachnoid hemorrhage from a large tertiary care center (2007–2022).RESULTSEighty‐one

Aneurysm 40

Aneurysm Hemorrhage Outcomes Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Background:Injury location is an established outcome predictor in intracerebral hemorrhage (ICH), with most studies focusing on outcomes relating to motor deficits. Data were analyzed by one-way ANOVA and Tukey post-hoc tests.Results:ICH location had differential effects on behavioral outcomes.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 27, 2024

The primary outcome was functional status measured by the modified Rankin Scale at 90 to 180 days. Earlier SBP control was associated with better functional outcomes (modified Rankin Scale score, 3–6; odds ratio, 0.98 [95% CI, 0.97–0.99]) Stroke, Ahead of Print. SD, 13.0], 2120 [36.8%] females) were included in analyses.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described. We compared the outcomes between patients with ICH associated with oral anticoagulants to those with spontaneous ICH.

Hemorrhage 40

Hemorrhage Outcomes Cardiovascular Disease Hypertension 40

Stroke Journal

DECEMBER 21, 2023

BACKGROUND:Cerebral cavernous malformation with symptomatic hemorrhage (SH) are targets for novel therapies. had at least one abnormal patient-reported outcome-measurement information system, Version 2.0 Functional outcomes and patient-reported outcomes generally improved over 2 years. At baseline, 62.6%

Hemorrhage 40

Hemorrhage Outcomes Quality of Life Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Pregnant patients are at risk of neurological complications including intracerebral hemorrhage (ICH). Stroke, Volume 55, Issue Suppl_1 , Page AWMP80-AWMP80, February 1, 2024. Pregnant patients experienced lower in-hospital mortality (12.4% vs 23.2%, p<0.001).

Hemorrhage 40

Hemorrhage Outcomes Kidney Disease Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Background:Cerebral vasospasm is a well-known complication after aneurysmal subarachnoid hemorrhage (aSAH) and occurs more commonly in younger patients. Worse outcome was defined as 3-month modified Rankin Scale 4-6. Vasospasm was defined based on transcranial Doppler (TCD) criteria. years [SD 13.3], 65% female and 70% white).

Atherosclerosis 40

Atherosclerosis Aneurysm Hemorrhage Outcomes 40

Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundDelayed cerebral ischemia represents a significant contributor to death and disability following aneurysmal subarachnoid hemorrhage. The lack of standardized experimental setups and outcome assessments, particularly regarding secondary vasospastic/ischemic events, may be partly responsible for the translational failure.

Ischemia 40

Ischemia Hemorrhage Blood Pressure Aneurysm 40

Stroke Journal

FEBRUARY 1, 2024

Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. The primary outcome was coma (GCS ≤ 8) at time of admission. These modifiable risk factors are an important therapeutic target for improving outcomes for patients with DoC.

Hemorrhage 40

Hemorrhage Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Background:Hyponatremia is the most common electrolyte abnormality seen in intracerebral hemorrhage (ICH) and is associated with a nearly doubled mortality rate and more severe presentations. This study showed that developing hyponatremia during the hospital stay was associated with worse outcomes at discharge.

Hemorrhage 40

Hemorrhage Inpatient Outcomes Diabetes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Both anticoagulants can be used intraoperatively and postoperatively for DVT prophylaxis in patients undergoing subarachnoid hemorrhage (SAH) treatment. Patients from both groups were assessed for baseline clinical characteristics, comorbidities, interventions, complications, and outcomes.

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Thrombosis 40

Stroke Journal

FEBRUARY 1, 2024

Current guidelines for blood pressure (BP) management in patients with intracerebral hemorrhage (ICH) recommend acute lowering of systolic BP (SBP) to 140 mm Hg with a maintenance goal of 130 - 150 mm Hg. Outcome was considered good if the patients were discharged home or had discharge mRS of 0-2.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

DAIC

FEBRUARY 26, 2024

The research group of Susanne Wegener, professor at the University of Zurich (UZH) and senior leading physician at the Department of Neurology of the University Hospital Zurich (USZ), has now demonstrated that the outcome of stroke treatments depends on the collateral network.

Blood Clot 105

Blood Clot Stroke Strokes Outcomes 105

HCPLive

JULY 24, 2024

A database analysis linked semaglutide use to notable reductions in the rates of diabetic macular edema and vitreous hemorrhage in diabetic retinopathy.

Diabetes 59

Diabetes Hemorrhage Outcomes 59

Stroke Journal

FEBRUARY 1, 2024

Recent landmark trials BEST-MSU and B_PROUD have proven that MSUs facilitate quicker thrombolysis times and improved functional outcomes at 90 days when compared to conventional emergency medical services (EMS) for acute ischemic stroke patients. Faster time metrics convey a hypothetical benefit towards improved patient outcomes.

Hemorrhage 40

Hemorrhage Blood Pressure Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Pregnancy is a risk factor for subarachnoid hemorrhage (SAH). We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).

Inpatient 40

Inpatient Aneurysm Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Prospective studies and secondary analyses from clinical trials have identified increased systolic blood pressure variability (SBPV) as a risk factor for poor outcomes. The primary outcome was severe disability or death (SDD; modified Rankin Scale ≥4) at 90-days after discharge.

Blood Pressure 40

Blood Pressure Hemorrhage Hospital Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. The occurrence of hemorrhagic change was assessed on CT after MT.

Hemorrhage 40

Hemorrhage Atrial Fibrillation Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Anticoagulation-associated intracerebral hemorrhage (AC-ICH) often results in death. For patients with available door-to-treatment (DTT) times, outcomes were analyzed using logistic regression models adjusted for demographic, history, baseline, and hospital characteristics.

Hemorrhage 40

Hemorrhage Blood Pressure Hospital Document 40

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundAsymptomatic intracerebral hemorrhage (aICH) occurs in approximately 35% of patients with acute ischemic stroke after endovascular thrombectomy. Unlike symptomatic ICH, studies evaluating the effect of aICH on outcomes have been inconclusive. Journal of the American Heart Association, Ahead of Print.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 18, 2024

Rigorous evidence generation with randomized controlled trials has lagged for aneurysmal subarachnoid hemorrhage (SAH) compared with other forms of acute stroke. Besides its lower incidence compared with other stroke subtypes, the presentation and outcome of patients with SAH also differ.

Hemorrhage 40

Hemorrhage Aneurysm Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Subarachnoid hemorrhage (SAH) is the deadliest form of hemorrhagic stroke. We propose the use of Oxygent, a perfluorocarbon (PFC) based lipid emulsion oxygen carrier, as a promising therapy to improve post-SAH functional outcomes. Stroke, Volume 55, Issue Suppl_1 , Page ATP303-ATP303, February 1, 2024.

Hemorrhage 40

Hemorrhage Ischemia Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Spontaneous intracerebral hemorrhages (ICH) remains the most devastating form of stroke. SCUBA patient was matched with control ICH patient who received standard medical treatment at 1:1 ratio by variables (hematoma volume and laterality, intraventricular hemorrhage [IVH] with hydrocephalus, age, NIHSS, GCS).

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Background:There are conflicting data on temporal trends in subarachnoid hemorrhage (SAH) incidence and outcomes. Aneurysmal SAH (aSAH) was defined as those with culprit aneurysms; cases with no available vessel imaging were considered aSAH if the hemorrhage volume was “massive” or if the patient died rapidly after onset.

Hemorrhage 40

Hemorrhage Aneurysm Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Cerebral vasospasm in non-traumatic subarachnoid hemorrhage (SAH) is associated with a high rate of morbidity and mortality. Demographics, comorbidities, and outcomes were identified. Functional outcome was categorized in Excellent, Good and Poor. ICD-10 I67.84) in non-traumatic SAH (ICD-9 430, ICD-10 I60).

Inpatient 40

Inpatient Hemorrhage Outcomes Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients. The primary outcome was utility weighted modified Rankin Scale (uw-mRS) at 90 days; secondary outcomes were hematoma expansion, length of inpatient stay, favorable discharge disposition or 90-day mRS, and mortality.

Hemorrhage 40

Hemorrhage Stroke Strokes Blood Pressure 40

Journal of the American Heart Association

FEBRUARY 7, 2024

Overall, we found a higher risk of hemorrhagic stroke for LDL‐C lowering, risk ratio (RR) 1.16 (95% CI, 1.01–1.32,P=0.03). Journal of the American Heart Association, Ahead of Print. We searched MEDLINE, Embase, and Cochrane Library up to July 2, 2021 and updated a meta‐analysis of cardiovascular statin trials published in 2012. 1.73) (Pint=0.14

Hemorrhage 40

Hemorrhage Stroke Strokes Cholesterol 40

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundThe impact of atrial fibrillation (AF) on the clinical outcomes in patients with acute ischemic stroke (AIS) who received endovascular thrombectomy remains unclear. Data were meta‐analyzed to compare the outcomes among patients with AIS with and without AF who received endovascular thrombectomy. 1.08]; [95% PI, 0.77–1.11]),

Atrial Fibrillation 45

Atrial Fibrillation Outcomes Hemorrhage Stroke 45

Stroke Journal

FEBRUARY 1, 2024

Introduction:Evaluating the prognosis of aSAH patients who may be at risk of poor outcomes using grading systems is one way to make a better decision on treatment for these patients. Finally, we used logistic regression to identify factors associated with the 90-day poor outcome.Results:Of 415 patients, 32% had a 90-day poor outcome.

Hemorrhage 40

Hemorrhage Outcomes Aneurysm Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Delayed cerebral ischemia (DCI) is a leading cause of morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH). The primary outcome was DCI, defined as an exclusionary change in GCS or new, none-treatment related infarcts on imaging. Stroke, Volume 55, Issue Suppl_1 , Page A114-A114, February 1, 2024.

Aneurysm 40

Aneurysm Hemorrhage ICU Ischemia 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Introductionintracranial dissecting aneurysm in pediatric age group is uncommon and very few studies are available comparing outcome following endovascular and surgery. Overall, 22 (88%) patients experienced a favorable outcome, while three (12%) had an unfavorable outcome during a mean follow‐up of 22.32 ± 7.43

Aneurysm 40

Aneurysm Pediatrics Outcomes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Background:The 2022 guidelines from the American Heart Association/American Stroke Association underscore the significance of coordinated multidisciplinary care and early discharge planning for spontaneous intracerebral hemorrhage (ICH) patients.

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40