Stroke Journal

MARCH 27, 2025

BACKGROUND:Stroke-induced opposite T-cell responses in the peri-lesion area and periphery worsen stroke outcomes by aggravating brain injury or increasing infectious complications, respectively. In this study, we investigated the causal link between TCRs and the opposite T-cell responses observed in intracerebral hemorrhage (ICH).METHODS:We

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

MARCH 7, 2025

BACKGROUND:Prior studies on the clinical impact of intracerebral hemorrhage (ICH) location have used visual localization of hematomas to neuroanatomical structures. In a voxel-wise analysis, ICH presence in deep white matter, thalami, caudate, midbrain, and pons was associated with worse outcomes. Stroke, Ahead of Print.

Hemorrhage 40

Hemorrhage Outcomes Risk Factors Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Patients who have had hemorrhagic strokes experience psychological and functional deficits after hospital discharge. Social Determinants of Health (SDoH) can also impact outcomes. Conclusion:Psychological and functional outcomes for patients with hemorrhagic strokes are associated with SDoH.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Managing post-acute hemorrhagic stroke care is complex and necessitates close follow-up and coordination. Primary outcome evaluated variables contributing to attendance of a neuroscience appointment post-discharge and secondary outcome: examined 90-day all cause readmission using binomial logistic regressions.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Intracerebral Hemorrhage (ICH) leads to high rates of morbidity and mortality. Malnutrition is common in stroke patients and leads to worse outcomes. Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results.

Hemorrhage 40

Hemorrhage BMI Outcomes Coronary Artery Disease 40

Stroke Journal

FEBRUARY 1, 2024

Our study aims to describe the trends and outcomes of patients with Subarachnoid Hemorrhage (SAH) using a Nationwide Inpatient Sample (NIS) database.Methods:We examined the 2016-2020 NIS database, focusing on patients aged 18 years and older with a primary SAH discharge diagnosis. years with 72,650 (61.0%) being female.

COVID-19 40

COVID-19 Hemorrhage Outcomes Inpatient 40

Stroke Journal

JANUARY 30, 2025

Background:The prognostic significance of the affected hemisphere in hemorrhagic stroke remains uncertain. We aimed to determine the relationship between the affected hemisphere (right or left) and differences in non-motor outcomes (pain, mood) in patients with acute intracerebral hemorrhage (ICH).

Quality of Life 40

Quality of Life Hemorrhage Outcomes Thrombolysis 40

DAIC

FEBRUARY 7, 2024

The results showed that giving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later. The study was looking for improvement in functional outcomes at 90 days. those receiving argatroban averaged 5.2,

Stroke 105

Stroke Strokes Outcomes Thrombolysis 105

Stroke Journal

FEBRUARY 1, 2024

Clinical characteristics, technical considerations associated with thrombectomy, severity and subtypes of HT (Heidelberg) and clinical outcomes were analyzed.Results:HT was adjudicated present in 70 out of 149 (47.0%) consecutive thrombectomy patients. Coexisting subtypes were present in 27.1 % of HT cases. of all patients and 11.4%

Hemorrhage 40

Hemorrhage Outcomes Thrombolysis Stroke 40

Stroke Journal

JANUARY 30, 2025

Introduction:Alzheimers Disease (AD), characterized by extracellular deposition of amyloid beta (A) plaques in brain tissue, is often comorbid with cerebral amyloid angiopathy, which carries an elevated risk of intracranial hemorrhage. Secondary outcomes were ICH, SAH, and SDH assessed separately. andICD-10-CMcode G30.x.

Hemorrhage 40

Hemorrhage Medicare Outpatient Inpatient 40

Stroke Journal

JANUARY 30, 2025

In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. We hypothesized that severe WMD in large vessel occlusion (LVO) stroke patients would correlate with worse 90-day functional outcomes, measured by the modified Rankin Scale (mRS).Methods:We

Hemorrhage 40

Hemorrhage Outcomes Hypertension Stroke 40

Stroke Journal

JANUARY 30, 2025

Introduction:Intracerebral hemorrhage (ICH) volume and expansion are important predictors of clinical outcome. Recent results show volumetric thresholds for prediction of poor outcome differ based on the anatomic location (lobar vs deep) of the ICH. Poor outcome was defined as modified Rankin Scale 4-6.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 1.02], p<0.001), higher NIS-Subarachnoid Hemorrhage Severity Score (NIS-SSS) (12.64 [4.21-37.95], Stroke, Volume 55, Issue Suppl_1 , Page ATP19-ATP19, February 1, 2024. 37.95], p<0.001), coagulopathy (5.72, [1.40-23.29],

Pediatrics 40

Pediatrics Hemorrhage Outcomes Hospital 40

Stroke Journal

JANUARY 30, 2025

Background and Issues:Timely identification and intervention are critical for positive outcomes in acute intracerebral hemorrhage (ICH) patients. Outcomes were measured using data for when the goals were being met versus not being met.Results:Outcomes were measured from 111 ICH patients from 2022-2023.

Hemorrhage 40

Hemorrhage Blood Pressure Outcomes ICU 40

Stroke Journal

JANUARY 30, 2025

The exposure was an incident diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage, subarachnoid hemorrhage, or subdural hemorrhage. The outcome was an incident diagnosis of dementia. million patients, 14,775 had a diagnosis of intracranial hemorrhage.

Dementia 40

Dementia Hemorrhage Medicare Outpatient 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Intraventricular hemorrhage (IVH), a common complication of intracerebral hemorrhage (ICH), can occur with little or no associated ICH (mostly IVH, mIVH). mIVH is reported to have better outcomes than IVH associated with substantial ICH. Age and IVH volume were final model independent predictors of good outcome.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Medical Xpress - Cardiology

OCTOBER 30, 2024

Findings from the first international randomized controlled trial to compare patient outcomes following treatment with large-bore mechanical thrombectomy (LBMT) versus catheter-directed thrombolysis (CDT) for intermediate-risk pulmonary embolism (PE) show that LBMT is superior with respect to the hierarchically-tested aggregated outcome of all-cause (..)

Embolism 52

Embolism Pulmonary ICU Outcomes 52

Stroke Journal

JANUARY 30, 2025

The exposure was a new diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and subdural hemorrhage (SDH). The outcome was a first-ever diagnosis of dementia. million patients, 14,775 had a diagnosis of intracranial hemorrhage.

Dementia 40

Dementia Hemorrhage Medicare Outpatient 40

HCPLive

JULY 24, 2024

A database analysis linked semaglutide use to notable reductions in the rates of diabetic macular edema and vitreous hemorrhage in diabetic retinopathy.

Diabetes 59

Diabetes Hemorrhage Outcomes 59

Stroke Journal

JANUARY 30, 2025

Background:Subarachnoid Hemorrhage (SAH) accounts for 2-7% of strokes and has high mortality and morbidity. We generated the co-expression networks using the Weighted Gene Co-Expression Network Analysis (WGCNA) package to determine modules (groups of co-expressed genes) associated with 90-day SAH outcome.

Hemorrhage 40

Hemorrhage Outcomes Biomarkers Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] 1.10]), top-quartile hemorrhage volume (2.89 [1.08-7.75]), female) with an ethno-racial distribution of 57.6%

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described. Less is known about disparities in risk and outcomes for young patients presenting with intracerebral hemorrhage (ICH), which is associated with higher short-term and long-term mortality. Asian, and 5.1%

Risk Factors 40

Risk Factors Hemorrhage Outcomes Inpatient 40

Stroke Journal

JANUARY 30, 2025

the 2023 calendar year, our comprehensive stroke metric for hemorrhagic stroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To the 2023 calendar year, our comprehensive stroke metric for hemorrhagic stroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To

Hemorrhage 40

Hemorrhage Stroke Strokes Document 40

Stroke Journal

FEBRUARY 1, 2024

Purpose:We previously reported that activated T cells accumulate in the perihematomal regions after Intracerebral hemorrhage (ICH) and aggravate hemorrhagic brain injury. Inhibiting TCR activation through AX-024 proves beneficial for improving neurological outcomes after ICH.

Hemorrhage 40

Hemorrhage Outcomes Pharmacology Stroke 40

Stroke Journal

MARCH 4, 2025

Subarachnoid hemorrhage is a critical neurological condition accounting for about 5% of all strokes, and survivors experience long-term cognitive deterioration and increased risk of dementia. Genetic predispositions have been associated with post-subarachnoid hemorrhage cognitive outcomes and emphasize a role for personalized care strategies.

Hemorrhage 40

Hemorrhage Genetic predisposition Genetic Markers Quality of Life 40

Stroke Journal

FEBRUARY 1, 2024

Background:Injury location is an established outcome predictor in intracerebral hemorrhage (ICH), with most studies focusing on outcomes relating to motor deficits. Data were analyzed by one-way ANOVA and Tukey post-hoc tests.Results:ICH location had differential effects on behavioral outcomes.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

BACKGROUNDThe rate of underlying ruptured aneurysms, complications, and their relevance to outcomes in “benign” perimesencephalic subarachnoid hemorrhage are not well known and underreported.METHODSRetrospective analysis of patients with perimesencephalic subarachnoid hemorrhage from a large tertiary care center (2007–2022).RESULTSEighty‐one

Aneurysm 40

Aneurysm Hemorrhage Outcomes Hospital 40

Stroke Journal

JANUARY 30, 2025

Background:A novel inflammatory score has been validated for hematoma expansion and poor outcomes in patients with intracerebral hemorrhage. Logistic regression models were used for exploring the association between inflammatory score and hemorrhagic transformation and poor outcomes.

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Stroke Journal

JANUARY 30, 2025

Introduction:Oxidative stress plays an important role in both early brain injury and delayed cerebral ischemia after subarachnoid hemorrhage (SAH). In this study, we evaluated the effect of MnP-05 on short-term outcomes of SAH in mice.Methods:We used 12-week-old male C57BL/6J mice. P<0.05, Fig.

Hemorrhage 40

Hemorrhage Outcomes Blood Pressure Ischemia 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Viscoelastic hemostatic assays can detect coagulopathy relevant for intracerebral hemorrhage (ICH) patients at risk for hematoma expansion. However, it is unclear whether these assays associate with long term ICH outcomes. Poor 6-month neurological outcome was defined as modified Rankin Scale (mRS) 4-6.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Background:Intracerebral hemorrhage (ICH) is a critical neurological condition with high rates of mortality and morbidity. Accurate prediction of the clinical outcomes in ICH patients is essential for effective clinical management. Spot sign was consistently identified as a robust predictor of outcomes across multiple studies.

Hemorrhage 40

Hemorrhage Outcomes Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical. The study found that GFAP levels were significantly higher in HS patients, particularly among those with fatal outcomes. Survivors had GFAP levels of 1.35

Hemorrhage 40

Hemorrhage Biomarkers Stroke Strokes 40

Stroke Journal

FEBRUARY 27, 2024

The primary outcome was functional status measured by the modified Rankin Scale at 90 to 180 days. Earlier SBP control was associated with better functional outcomes (modified Rankin Scale score, 3–6; odds ratio, 0.98 [95% CI, 0.97–0.99]) Stroke, Ahead of Print. SD, 13.0], 2120 [36.8%] females) were included in analyses.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 9, 2024

The primary outcome was good functional outcome at 3 months. The secondary outcomes included excellent functional outcome at 3 months and early neurological improvement. The odds ratio (OR) of good functional outcome at 3 months was 0.93 (95% CI, 0.68–1.28) The OR of excellent functional outcome (OR 1.23; 95% CI 0.92–1.64)

Hemorrhage 75

Hemorrhage Article Outcomes Stroke 75

Stroke Journal

FEBRUARY 1, 2024

Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described. We compared the outcomes between patients with ICH associated with oral anticoagulants to those with spontaneous ICH.

Hemorrhage 40

Hemorrhage Outcomes Cardiovascular Disease Hypertension 40

Stroke Journal

DECEMBER 15, 2023

Intracerebral hemorrhage is the most serious type of stroke, leading to high rates of severe disability and mortality. Hematoma expansion is an independent predictor of poor functional outcome and is a compelling target for intervention. Stroke, Ahead of Print.

Best Practices 75

Best Practices Hemorrhage Blood Pressure Innovation 75

Journal of the American Heart Association

DECEMBER 18, 2023

Outcomes included symptomatic intracranial hemorrhage, any intracranial hemorrhage, serious systemic bleeding, and 90‐day functional independence (modified Rankin scale score 0–2). The rates of symptomatic intracranial hemorrhage (3.4 1.36]), any intracranial hemorrhage (17.7 versus 3.5%; OR, 0.95 [95% CI, 0.67–1.36]),

Thrombolysis 75

Thrombolysis Hemorrhage Stroke Strokes 75