Remove Hemorrhage Remove Ischemia Remove Stroke
article thumbnail

Abstract WP370: Platelet morphology but not coagulation markers predicts delayed cerebral ischemia after subarachnoid hemorrhage

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP370-AWP370, February 1, 2025. Approximately 30% of aneurysmal subarachnoid hemorrhage (aSAH) patients who survive the rupture develop delayed cerebral ischemia (DCI) 4 to 10 days following aSAH.

article thumbnail

Abstract WP35: Neutrophil Extracellular Traps As a Biomarker for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). In this study, our hypothesis was that markers of NETs are higher in aneurysmal SAH patients developing DCI compared to SAH patients not developing DCI.

article thumbnail

ECG Changes in Intracranial Hemorrhage

All About Cardiovascular System and Disorders

ECG Changes in Intracranial Hemorrhage ECG changes are fairly common in intracranial hemorrhage. Giant T inversions with QT interval prolongation may be seen in intracranial hemorrhage even without associated myocardial damage [1]. But the number of persons with lobar hemorrhage in that study was only 17%. Am Heart J.

article thumbnail

Abstract WP213: An experimental and theoretical study on electrical brain stimulation for post Intracerebral Hemorrhagic stroke rehabilitation.

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP213-AWP213, February 1, 2025. Intracerebral Hemorrhagic (ICH) stroke is the second most common type of stroke and its aftermath is often more severe than ischemia. Neural activity (Electrophysiological) data is collected pre/post stroke and during stimulation.

article thumbnail

Abstract WMP112: Neutrophil Extracellular Traps Occlude the Cerebrovasculature Causing Delayed Cerebral Ischemia After Subarachnoid Hemorrhage in Mice

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWMP112-AWMP112, February 1, 2024. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). Following ischemic stroke, neutrophils cause vascular occlusion via neutrophil extracellular traps (NETs).

article thumbnail

Abstract TMP5: The Impact of Enteral Nimodipine on Endothelial Cell Apoptosis in an Animal Subarachnoid Hemorrhage Model

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATMP5-ATMP5, February 1, 2025. Background:Enteral nimodipine is the most evidence-based and widely used drug for the treatment of delayed cerebral ischemia and is known to have various neuroprotective functions. Endothelial desquamation was observed only in the SAH-saline group.

article thumbnail

Abstract WP220: Assessing the Therapeutic Time Window for Tranexamic Acid in Intracerebral Hemorrhage – A Systematic Review and Meta-analysis

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP220-AWP220, February 1, 2025. Background:Several studies have shown that tranexamic acid (TXA), an anti-fibrinolytic agent, may reduce hematoma expansion (HE) in intracerebral hemorrhage (ICH), but its therapeutic time window is unclear. to 0.97; p= 0.02; I2= 0%). mL; 95% CI -3.15