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Despite advances in surgical and percutaneous interventions, hypertension remains a significant complication in AoC patients, even after successful repair. Chronic hypertension develops in 20%70% of patients and is a leading cause of long-term cardiovascular morbidity.
BACKGROUNDLocal angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, and impaired arterial wall integrity contributes to the pathogenesis of subarachnoid hemorrhage (SAH). The primary outcome was the subsequent development of nontraumatic SAH. million, followup: 6.3 million, followup: 5.7
Introduction:Cerebrovascular white matter disease (WMD) severity is linked to vascular risk factors like hypertension, hyperlipidemia, and diabetes. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. 1.26) or 90d mRS shift (cOR 1.50, 95%CI 0.74-3.04,
Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described. Less is known about disparities in risk and outcomes for young patients presenting with intracerebral hemorrhage (ICH), which is associated with higher short-term and long-term mortality. Asian, and 5.1%
Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical. The study found that GFAP levels were significantly higher in HS patients, particularly among those with fatal outcomes. Survivors had GFAP levels of 1.35
Clinical and neuroimaging predictors of an unfavorable discharge outcome (modified Rankin score 4) were assessed in univariate and multivariable models.Results:Between 2003 and 2019, 1,791 patients were admitted with non-traumatic ICH. Introduction:The recent update (version 2.0)
Introduction:Pregnant patients are at risk of neurological complications including intracerebral hemorrhage (ICH). vs 63.38, p<0.001) and had fewer comorbidities such as cancer and chronic kidney disease, atrial fibrillation, hypertension, hyperlipidemia. Stroke, Volume 55, Issue Suppl_1 , Page AWMP80-AWMP80, February 1, 2024.
Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described. We compared the outcomes between patients with ICH associated with oral anticoagulants to those with spontaneous ICH.
Contributing factors such as hypocholesterolemia and hypertension amplify the risk of ICH and subsequent hematoma expansion, underscoring the urgent need for effective interventions. Standardized studies are imperative to inform evidence-based clinical decisions and improve outcomes for individuals afflicted with intracranial hemorrhage.
Recent landmark trials BEST-MSU and B_PROUD have proven that MSUs facilitate quicker thrombolysis times and improved functional outcomes at 90 days when compared to conventional emergency medical services (EMS) for acute ischemic stroke patients. The majority (77%) of MSU patients received anti-hypertensive medications while in the MSU.
Background and Objectives:It is unclear whether induced hypertension in acute ischemic stroke (AIS) may improve long-term outcomes. The safety outcome was symptomatic intracranial hemorrhage (sICH). Stroke, Volume 55, Issue Suppl_1 , Page ATMP61-ATMP61, February 1, 2024. Mean age was 66.6 3.11; p=0.01). 7.45; p=0.98).Discussion:Among
The primary outcome was a composite of the incidence of myocardial infarction and ischemic and hemorrhagic stroke, obtained by tracking the medical use data of the first-ever ICD-10 codes. Circulation, Volume 150, Issue Suppl_1 , Page A4113411-A4113411, November 12, 2024. years and median follow-up duration was 15.9
Background:Cerebral vasospasm in non-traumatic subarachnoid hemorrhage (SAH) is associated with a high rate of morbidity and mortality. Demographics, comorbidities, and outcomes were identified. Functional outcome was categorized in Excellent, Good and Poor. ICD-10 I67.84) in non-traumatic SAH (ICD-9 430, ICD-10 I60).
We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. The occurrence of hemorrhagic change was assessed on CT after MT.
Introduction:Intracerebral hemorrhage (ICH) is a major cause of maternal mortality, but its pathophysiology is not well characterized. Participants were identified from an internal stroke registry and through the ICHOP (Intracerebral HemorrhageOutcomes Project) study. secondary) ICH (adjusted OR 4.9,
Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients. The primary outcome was utility weighted modified Rankin Scale (uw-mRS) at 90 days; secondary outcomes were hematoma expansion, length of inpatient stay, favorable discharge disposition or 90-day mRS, and mortality.
Introduction:Patients with intracerebral hemorrhage (ICH) often undergo CT and CT angiography with the latter being done to identify vascular abnormalities for ICH etiology. Demographics, comorbidities, and clinical outcomes were also recorded. Stroke, Volume 55, Issue Suppl_1 , Page ATP157-ATP157, February 1, 2024.
Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH. Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025.
IntroductionSubarachnoid hemorrhage (SAH) has an estimated prevalence of 7.9 Thus, there is a need to study and comprehend the management strategies and outcomes of these cases. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. per 100,000 person yearsi. were intervened on.
Objectives:Mixed location intracerebral hemorrhages/ microbleeds (CMBs) (mixed ICH) is referred to as potential hypertensive arteriolosclerosis/cerebral amyloid angiopathy (CAA) combination, reflecting small vessel disease (SVD) burden. There were no significant differences in hypertension, dyslipidemia, and diabetes.
Introduction:Cerebral amyloid angiopathy (CAA) is an age-related cerebral small vessel disease that can lead to poor outcomes due to cerebral hemorrhage. The same applies to hypertensive cerebral small vessel disease (HTN-CSVD). Stroke, Volume 56, Issue Suppl_1 , Page AWP188-AWP188, February 1, 2025.
Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. We performed this retrospective cohort analysis to assess the impact of poorly controlled diabetes, defined as HbA1C of 9.0% or greater. vs. 20.5%; p = 0.048) and stenting (28.4%
1) Nevertheless, published research on endovascular treatment outcomes in this population is scarce. 2, 3) In this study, we compared the clinical outcomes of TL patients with the two etiologies.MethodsA retrospective analysis was performed on a multicenter cohort of patients with TLs who underwent endovascular treatment.
Introduction:Effective care transition for ischemic or hemorrhagic stroke patients post-hospital discharge is critical. Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke risk factors like hypertension, diabetes, and atrial fibrillation.
We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensivehemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls. P=0.032).
Primary outcome: door to needle (DTN) time of the APP versus neurology residents using quantile (median) regression adjusted for age, NIHSS and delays for treating hypertension. Secondary outcome evaluated symptomatic intracranial hemorrhage (sICH) post thrombolysis comparing APP versus neurology residents using Fishers exact test.
Introduction:Transcranial Doppler Ultrasound (TCD) has proven to be useful in monitoring vasospasm after intracerbral hemorrhage (ICH), predicting delayed ischemic stroke (AIS) (sensitivity 91.2%, specificity 80.8%), and assessing recanalization post-thrombolysis for AIS. (91%, 1.3), hypertensives(1.05, 1.01-1.1),
In light of postoperative CT head showing SAH in the basilar, perimesencephalic, prepontine cisterns, interhemispheric fissure and right frontal sulci as well as intraventricular hemorrhage in fourth ventricle, her presentation was thought to be secondary to cerebral vasospasm in the setting of postoperative SAH.
Patients with a modified Rankin score of 3-5 were offered enrollment in the Stroke Transitions Program (intervention group). Patients were also provided with the stroke nurses direct contact information to help navigate the healthcare system.
1,2 The National Institute of Health Stroke Scale (NIHSS) cutoff for poor outcomes is lower in BAO compared to anterior circulation large vessel occlusions (LVO) due to the scale’s weighted scoring towards cortical signs.3,4 3,4 To bridge this gap, Alemseged et.al
Cerebral AVMs may manifest with new‐onset seizures or intraparenchymal (IPH) or subarachnoid hemorrhages (SAH). Regular monitoring of these structures and adjacent vessels is required to prevent any poor outcomes. Life‐threatening bleeds may occur from the AVM nidus or associated aneurysms.
Massive Transfusion for Motorcycle Collision with Hemorrhage, Troponin Elevated. Atrial fibrillation is also a predictor of worse outcomes in this case (Alborzi). Q waves in association with RBBB are usually not seen in anterior leads unless there is pulmonary hypertension or anterior infarction.
Case submitted and written by Mazen El-Baba MD, with edits from Jesse McLaren and edits/comments by Smith and Grauer A 90-year old with a past medical history of atrial fibrillation, type-2 diabetes, hypertension, dyslipidemia, presented with acute onset chest/epigastric pain, nausea, and vomiting. BP was 110 and oxygen saturation was normal.
Hypertension, Ahead of Print. Background:After a large intracerebral hemorrhage (ICH), the hematoma and swelling cause intracranial pressure (ICP) to increase, sometimes causing brain herniation and death.
Disparities in outcomes of patients with ischemic stroke have been associated with insurance coverage. However, there are few studies investigating the impact of insurance status on outcomes in patients with intracerebral hemorrhage (ICH).Methods:We Table 1 illustrates demographics by insurance status. 2.03, p=0.022, Figure 1).
Introduction:Education, a key modifiable social determinant of health, plays a significant role in shaping outcomes related to ischemic stroke. The predicted probability of good outcome by education level was significantly different (Figure 1). See Table 1 for demographics by education group. 3.85, p=0.002).Conclusion:Our
Background:It remains unknown which social determinants of health (SDOH) are impactful or when disparities begin to emerge in intracerebral hemorrhage (ICH). The primary outcome was the modified Rankin Score (mRS) measured at 12 months. SDOH exposures included income bracket, educational attainment, marital status, race, and religion.
Background:Ischemic lesions on diffusion weighted imaging (DWI) occur in one-third of intracerebral hemorrhage (ICH). Patients with severe, chronic hypertension may be more vulnerable to the development of ischemia after ICH due to altered cerebral autoregulatory limits. and LVH was seen in 23.5%.
Introduction and Objective:Lobar cerebral microbleed (CMB) is frequently found in patients with spontaneous intracerebral hemorrhage (ICH) and is closely linked to cerebral amyloid angiopathy (CAA) and risk of recurrent ICH. 11.75], p=0.015) and composite outcomes (HR 2.55[1.26-5.17], 11.75], p=0.015) and composite outcomes (HR 2.55[1.26-5.17],
Introduction:The influence of social determinants of health (SDH) is well-documented across a range of medical conditions and health outcomes. Less clear is the impact of SDH on patient-reported outcomes, particularly mental health outcomes, in intracerebral hemorrhage (ICH).
Introduction:Incident intracerebral hemorrhage (ICH) is an uncommon medical event that can lead to devastating outcomes, including death. CMBs result from irregularities in brain vessel structure due to chronic hypertension and cerebral amyloid angiopathy. Stroke, Volume 55, Issue Suppl_1 , Page ATMP79-ATMP79, February 1, 2024.
However, there is a lack of understanding whether specific migraine features like white matter hyperintensities (WMH) commonly found on brain magnetic resonance (MR) imaging in migraine patients and migraine medications might contribute to Major Adverse Cardiovascular Event (MACE) outcomes including ischemic and hemorrhagic stroke.
Hypertension, Ahead of Print. We used mixed effects regression models to identify associations between trajectory groups and outcomes adjusting for potential confounders and reported the respective adjusted odds ratios (aORs) and common odds ratios.RESULTS:There were 2640 total patients with acute ischemic stroke included in the analysis.
Introduction:Chronic kidney disease (CKD) is a risk factor for intracerebral hemorrhage (ICH) and for worse outcomes following ICH. For each patient, eGFR along with age, sex, race, ethnicity, hypertension, diabetes (DM), heart disease, and hyperlipidemia were abstracted.
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