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BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). Among patients with AA-ICH, there were no differences in the proportion with lobar hemorrhage (63/148 [42.6%] versus 46/107 [43.0%]; OR, 1.02 [95% CI, 0.62–1.68];P=0.946)
Background:Local angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, which contributes to the pathogenesis of subarachnoid hemorrhage (SAH). million patients with hypertension were assessed. million patients with hypertension were assessed. million,follow-up:6.3 female) [HR:0.94(0.91-0.97),
BACKGROUNDLocal angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, and impaired arterial wall integrity contributes to the pathogenesis of subarachnoid hemorrhage (SAH). million patients with hypertension were assessed. million, followup: 6.3 million, followup: 5.7 million, followup: 5.3
Hypertension, Ahead of Print. Background:After a large intracerebral hemorrhage (ICH), the hematoma and swelling cause intracranial pressure (ICP) to increase, sometimes causing brain herniation and death.
Hypertension, Ahead of Print. ETs were shown to play important roles among others, in systemic hypertension, particularly when resistant or difficult to control, and in pulmonary hypertension, atherosclerosis, cardiac hypertrophy, subarachnoid hemorrhage, chronic kidney disease, diabetic cardiovascular disease, scleroderma, some cancers, etc.
Introduction:Chronic kidney disease (CKD) is a well-established risk factor for spontaneous intracerebral hemorrhage (ICH). This association was reduced to a 19% increase in ICH risk after adjusting for hypertension in multivariable MR (OR 1.19; 95% CI 1.03-1.39; Stroke, Volume 55, Issue Suppl_1 , Page AWP159-AWP159, February 1, 2024.
Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical. Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025.
Introduction:Cerebrovascular white matter disease (WMD) severity is linked to vascular risk factors like hypertension, hyperlipidemia, and diabetes. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. Stroke, Volume 56, Issue Suppl_1 , Page ATP170-ATP170, February 1, 2025.
Introduction:Superficial (gray matter, vermis) cerebellar intracerebral hemorrhage (cICH) is associated with strictly lobar supratentorial cerebral microbleeds—a strong marker for cerebral amyloid angiopathy. Of these, 83 (64%) patients had deep cICH and 46 (36%) patients had superficial cICH.
Contributing factors such as hypocholesterolemia and hypertension amplify the risk of ICH and subsequent hematoma expansion, underscoring the urgent need for effective interventions. Standardized studies are imperative to inform evidence-based clinical decisions and improve outcomes for individuals afflicted with intracranial hemorrhage.
The majority (77%) of MSU patients received anti-hypertensive medications while in the MSU. In the EMS cohort, only patients seen between 8 am to 8 pm, corresponding to the operating hours of the MSU, were included. Initial systolic blood pressure in the hospital was significantly higher for EMS compared to MSU patients (166 vs 157, p=0.011).
The main risk factor is hypertension, and blood pressure (BP) control is crucial in the primary and secondary prevention of stroke. Individuals self-reported previous medical history of stroke (including TIA, ischemic and hemorrhagic stroke), hypertension, medication intake, and other vascular risk factors.
Background:TheGallele ofFOXO3SNPrs2802292,which is associated with human resilience and longevity, has been shown to attenuate the impact of hypertension on the risk of intracerebral hemorrhage. We sought to determine whether theFOXO3 G-allele similarly attenuates the impact of hypertension on the risk of cerebral microinfarcts (CMI).Methods:From
Background and Objectives:It is unclear whether induced hypertension in acute ischemic stroke (AIS) may improve long-term outcomes. The safety outcome was symptomatic intracranial hemorrhage (sICH). sICH did not differ between patients treated with induced hypertension (<1%) versus control (<1%) (OR 1.03; 95% CI 0.14-7.45;
Background and Purpose:Intracerebral and subarachnoid hemorrhages comprise roughly 15% of all strokes but have a higher risk of mortality and morbidity than ischemic strokes. Controlling hypertension after a hemorrhage is the primary intervention to limit the risk of hematoma expansion (HE) and the sequelae of secondary injury.
There is a critical lack of data about early life stroke risk factors among Black women, a group with higher rates of hypertension compared to other racial groups. Ischemic and hemorrhagic stroke were ascertained by self-report at biennial health questionnaires. range 24-64] years).
There is a critical lack of data about early life stroke risk factors among Black women, a group with higher rates of hypertension compared to other racial groups. Ischemic and hemorrhagic stroke were ascertained by self-report at biennial health questionnaires. range 24-64] years).
BACKGROUND:Cerebellar intracerebral hemorrhage (cICH) is often attributed to hypertension or cerebral amyloid angiopathy (CAA). 36.73];P=0.01), hypertension (84.4% Stroke, Volume 54, Issue 12 , Page 3074-3080, December 1, 2023. However, deciphering the exact etiology can be challenging. versus 3.4%; OR, 41.39 [95% CI, 5.01–341.68];P=0.001),
Introduction:Intracerebral hemorrhage (ICH) is a major cause of maternal mortality, but its pathophysiology is not well characterized. Participants were identified from an internal stroke registry and through the ICHOP (Intracerebral Hemorrhage Outcomes Project) study. secondary) ICH (adjusted OR 4.9,
Introduction:Incident intracerebral hemorrhage (ICH) is an uncommon medical event that can lead to devastating outcomes, including death. CMBs result from irregularities in brain vessel structure due to chronic hypertension and cerebral amyloid angiopathy. Stroke, Volume 55, Issue Suppl_1 , Page ATMP79-ATMP79, February 1, 2024.
Introduction:Patients with intracerebral hemorrhage (ICH) often undergo CT and CT angiography with the latter being done to identify vascular abnormalities for ICH etiology. Univariate logistic regression estimated unadjusted effects of ICH type, age, hypertension (HTN), and other predictors on the logit of vascular abnormalities.
Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH. Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025.
IntroductionAneurysmal subarachnoid hemorrhage (aSAH) accounts for about 10% of hemorrhagic strokes [1] and holds a high mortality and morbidity rate. [2, Head CT on arrival showed a diffuse subarachnoid hemorrhage, more prominent in the posterior fossa, and grade IV on the modified Fisher scale.
We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. The occurrence of hemorrhagic change was assessed on CT after MT.
Outcomes of MSU management in patients with intracranial hemorrhage (ICH) have not been reported.Methods:We conducted a retrospective review of ICH patients enrolled in the Benefits of Stroke Treatment Using a Mobile Stroke Unit (BEST-MSU), a prospective multicenter controlled trial comparing MSU with standard EMS management (SM).
Introduction:Intracerebral Hemorrhage (ICH) is a significant type of stroke, being the second most common and with a higher risk of mortality and morbidity compared to ischemic stroke. Stroke, Volume 56, Issue Suppl_1 , Page AHUP13-AHUP13, February 1, 2025.
Less is known about disparities in risk and outcomes for young patients presenting with intracerebral hemorrhage (ICH), which is associated with higher short-term and long-term mortality. Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described.
The timing of ischemic stroke (IS) and hemorrhagic stroke (HS) in relation to MPN diagnosis among Veterans remains undefined.We utilized the Veterans Affairs Informatics and Computing Infrastructure database from 1/1/2006 - 1/26/2023 and included 586,555 Veterans from Illinois, the state most representative of the US population.
IntroductionSubarachnoid hemorrhage (SAH) has an estimated prevalence of 7.9 Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. per 100,000 person yearsi. It is primarily caused by the rupture of intracranial aneurysms, leading to severe consequences and a 60% 6‐month mortality rateii. were intervened on.
IntroductionSubarachnoid Hemorrhage (SAH) is the leading cause of morbidity and mortality in stroke patients, associated with severe neurological, infectious, and thromboembolic complications. Further studies are required to offer risk stratification and prevention strategies for readmission among patients with Subarachnoid Hemorrhage.
Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described. Stroke, Volume 55, Issue Suppl_1 , Page AWP209-AWP209, February 1, 2024.
Cases had a maternal stroke (ischemic, hemorrhagic, subarachnoid hemorrhage, or cerebral venous thrombosis) during pregnancy or PP, identified from a stroke registry.
Introduction:Pregnant patients are at risk of neurological complications including intracerebral hemorrhage (ICH). vs 63.38, p<0.001) and had fewer comorbidities such as cancer and chronic kidney disease, atrial fibrillation, hypertension, hyperlipidemia. Stroke, Volume 55, Issue Suppl_1 , Page AWMP80-AWMP80, February 1, 2024.
Objectives:Spontaneous intracerebral hemorrhage (ICH) is caused by the rupture of small arterioles due to cerebral small vessel disease (SVD), commonly with hypertensive arteriolosclerosis (HTA) or cerebral amyloid angiopathy (CAA). Stroke, Volume 56, Issue Suppl_1 , Page ATMP63-ATMP63, February 1, 2025.
BACKGROUND:Long-term patterns of functional outcome after intracerebral hemorrhage (ICH) have not been well elucidated in population-based studies from low- and middle-income countries. Stroke, Ahead of Print. The proportion of favorable outcomes increased from 12.1% at day 28 to 17.4% at day 90 and then to 23.0%
Background:The 2023 American Heart Association/American Stroke AssociationsGuideline for Management of Patients with Aneurysmal Subarachnoid Hemorrhage(SAH) support use of the Ottawa Rule to screen individuals at risk. The ED lacked a formal triage process for identification of SAH resulting in delayed treatment.
The primary outcome was a composite of the incidence of myocardial infarction and ischemic and hemorrhagic stroke, obtained by tracking the medical use data of the first-ever ICD-10 codes. Circulation, Volume 150, Issue Suppl_1 , Page A4113411-A4113411, November 12, 2024. years and median follow-up duration was 15.9
Qualitative data were compared by chi-square tests.Among 586,555 Veterans from Illinois, there were 15,455 ischemic stroke (IS), 1,593 hemorrhagic stroke (HS), 2,752 MPN, and 59,393 with AO exposure. AO exposure was verified on the Veterans’ service duration and location. Among MPNs, there were 237 IS (41 with AO) and 26 HS (3 with AO).
Patients with a high risk of metabolic syndrome (>= 2 of the following: hypertension, diabetes, hyperlipidemia, or obesity) have a higher risk of AIS (1.37, 1.13 - 1.65), AMI (1.81, 1.19 - 2.75), and MACE (1.28, 1.13 - 1.44).Conclusions:Developing
Introduction:Cerebral amyloid angiopathy (CAA) is an age-related cerebral small vessel disease that can lead to poor outcomes due to cerebral hemorrhage. The same applies to hypertensive cerebral small vessel disease (HTN-CSVD). Stroke, Volume 56, Issue Suppl_1 , Page AWP188-AWP188, February 1, 2025.
Background:Cerebral vasospasm in non-traumatic subarachnoid hemorrhage (SAH) is associated with a high rate of morbidity and mortality. Patients with seizures were more likely to be White or Hispanic, and to have systemic inflammatory disease, hyperlipidemia and hypertension (all p<0.001). vs. 7.70 ± 7.77; p<0.001).
Transcript of the video: Eisenmenger syndrome is an important complication of large left to right shunts which develop later due to development of pulmonary vascular obstructive disease and severe pulmonary hypertension. This highlights one of the most important complications of Eisenmenger syndrome, that is airway hemorrhage.
It has articles, ranging from from simple clinical studies on postpartum hemorrhage (E-MOTIVE study) from deep inside Africa by Melinda Gate foundation, to Dupilumab for COPD, a stunning monoclonal antibody inhibitor of IL-4 for COPD exacerbations.
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