ECG Cases

NOVEMBER 28, 2023

On this month's EM Quick Hits podcast: Anand Swaminathan on update to ED management of postpartum hemorrhage, Nour Khatib on serotonin syndrome and its mimics, Katie Lin on an approach to recognition and management of severe TBI and brain herniation syndromes, Hans Rosenberg on the ED management of ulcerative colitis, Heather Cary on pediatric c-spine (..)

Pediatrics 110

Pediatrics Hemorrhage 110

Journal of Clinical Investigation - Cardiology

FEBRUARY 1, 2024

Microscopic hemorrhage is a common aspect of cancers, yet its potential role as an independent factor influencing both cancer progression and therapeutic response is largely ignored. These cells resembled antiinflammatory erythrophagocytic macrophages.

Cancer 98

Cancer Hemorrhage 98

ECG Cases

MAY 28, 2024

Once the diagnosis of nontraumatic subarachnoid hemorrhage (SAH) has been made, our job is not done. When is a CT plus CTA of the head indicated up front in the management of patients with suspected subarachnoid hemorrhage? What can we do in the ED to prevent rebleeding in patients with subarachnoid hemorrhage?

Hemorrhage 52

Hemorrhage Outcomes 52

Stroke Journal

OCTOBER 2, 2024

BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). Among patients with AA-ICH, there were no differences in the proportion with lobar hemorrhage (63/148 [42.6%] versus 46/107 [43.0%]; OR, 1.02 [95% CI, 0.62–1.68];P=0.946)

Hemorrhage 40

Hemorrhage Blood Pressure Hypertension Hospital 40

Medical Xpress - Cardiology

JULY 3, 2024

This makes it particularly interesting for preclinical treatment of hemorrhagic shock. Relatively small volume injections of solutions of a novel star-shaped polymer could compensate for the loss of fluid without disrupting coagulation, according to a new study published in the journal Angewandte Chemie International Edition.

Hemorrhage 90

Hemorrhage Research 90

Medical Xpress - Cardiology

FEBRUARY 14, 2024

Taking an anticoagulant, or blood-thinning medication, can increase one's risk of—or exacerbate—a brain bleed, also known as a brain hemorrhage, which is the deadliest type of stroke. Now, new research finds that faster treatment for these patients is associated with a greater likelihood of survival.

Hemorrhage 90

Hemorrhage Research Stroke Strokes 90

All About Cardiovascular System and Disorders

NOVEMBER 16, 2023

ECG Changes in Intracranial Hemorrhage ECG changes are fairly common in intracranial hemorrhage. Giant T inversions with QT interval prolongation may be seen in intracranial hemorrhage even without associated myocardial damage [1]. But the number of persons with lobar hemorrhage in that study was only 17%. Am Heart J.

Hemorrhage 52

Hemorrhage Myocardial Infarction Aneurysm Electrocardiogram 52

American College of Cardiology

MAY 22, 2024

What is the effect of andexanet alfa, a reversal agent for factor Xa inhibitors, on hematoma volume expansion in patients with intracerebral hemorrhage?

Hemorrhage 58

Hemorrhage Article 58

Stroke Journal

FEBRUARY 1, 2024

Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] 1.10]), top-quartile hemorrhage volume (2.89 [1.08-7.75]), female) with an ethno-racial distribution of 57.6% Hispanic, 8.5%

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Frontiers in Cardiovascular Medicine

JANUARY 8, 2024

Nevertheless, the patient developed hemorrhagic PT due to acute pericarditis 2 weeks later, which was confirmed by cardiac magnetic resonance, requiring an urgent pericardiocentesis. Conclusions We encountered a unique case of COVID-19-associated acute pericarditis exhibiting hemorrhagic PT.

COVID-19 72

COVID-19 Pericarditis Hemorrhage Hospital 72

Stroke Journal

MAY 2, 2024

The American Heart Association/American Stroke Association released a revised spontaneous intracerebral hemorrhage guideline in 2022. These 15 performance measures encompass a wide spectrum of intracerebral hemorrhage patient care, from prehospital to posthospital settings, highlighting the importance of timely interventions.

Hemorrhage 75

Hemorrhage Stroke Strokes Patient Care 75

Stroke: Vascular and Interventional Neurology

FEBRUARY 19, 2024

BACKGROUNDThe rate of underlying ruptured aneurysms, complications, and their relevance to outcomes in “benign” perimesencephalic subarachnoid hemorrhage are not well known and underreported.METHODSRetrospective analysis of patients with perimesencephalic subarachnoid hemorrhage from a large tertiary care center (2007–2022).RESULTSEighty‐one

Aneurysm 40

Aneurysm Hemorrhage Outcomes Hospital 40

Journal of the American Heart Association

DECEMBER 29, 2023

BackgroundThe outcome of diffuse angiogram‐negative subarachnoid hemorrhage (dan‐SAH) compared with aneurysmal SAH (aSAH) remains unclear. 4.64];P<0.001), presence of intraventricular hemorrhage (OR, 3.58 [95% CI, 1.72–7.46];P=0.001), 4.64];P<0.001), presence of intraventricular hemorrhage (OR, 3.58 [95% CI, 1.72–7.46];P=0.001),

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Ischemia 40

Cardiovascular Diabetology

MARCH 17, 2024

Hemorrhagic stroke (HS), including non-traumatic intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), constitutes a substantial proportion of cerebrovascular incidents, accounting for around 30% o.

Hemorrhage 52

Hemorrhage Stroke Strokes Research 52

Stroke Journal

FEBRUARY 1, 2024

A pairwise comparison of PiB and FTP uptake was done between lobes with any hemorrhagic lesion (ICH/cSS) and their corresponding lobes without hemorrhages.Results:The FTP uptake was significantly higher in 8 frontal, 16 temporal, and 11 occipital lobes with hemorrhages compared to their corresponding contralateral lobes without hemorrhages (1.18±0.1

Hemorrhage 40

Hemorrhage Stroke Strokes 40

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

Hereditary hemorrhagic telangiectsia (HHT) is an inherited vascular disorder with highly variable expressivity, affecting up to 1 in 5,000 individuals. This disease is characterized by small arteriovenous malformations (AVMs) in mucocutaneous areas (telangiectases) and larger visceral AVMs in the lungs, liver, and brain.

Hemorrhage 56

Hemorrhage 56

Stroke Journal

FEBRUARY 1, 2024

Radiologic subtypes were: hemorrhagic infarction (HI-1) (51.4%), HI-2 (25.7%), parenchymal hematoma (PH-1) (4.3%), PH-2 (4.3%), subarachnoid hemorrhage (SAH) (34.3%), intraventricular hemorrhage (IVH) (12.8%), and subdural hemorrhage (SDH) (0%). Coexisting subtypes were present in 27.1 % of HT cases.

Hemorrhage 40

Hemorrhage Outcomes Thrombolysis Stroke 40

All About Cardiovascular System and Disorders

FEBRUARY 2, 2024

What are the ECG Changes in Intracranial Hemorrhage?

Hemorrhage 52

Hemorrhage Electrophysiology 52

Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundDelayed cerebral ischemia represents a significant contributor to death and disability following aneurysmal subarachnoid hemorrhage. In murine studies (n=30), the endovascular perforation model was predominantly used, while rat studies primarily employed intracisternal blood injection to mimic subarachnoid hemorrhage.

Ischemia 40

Ischemia Hemorrhage Blood Pressure Aneurysm 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Patients who have had hemorrhagic strokes experience psychological and functional deficits after hospital discharge. Conclusion:Psychological and functional outcomes for patients with hemorrhagic strokes are associated with SDoH. Stroke, Volume 55, Issue Suppl_1 , Page AWP164-AWP164, February 1, 2024.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. Results:We included 314 patients admitted with intracranial hemorrhage, 51 (16%) of whom had GCS ≤ 8 at time of admission, 51% female and median [interquartile (IQR)] age of 63 [51-73].

Hemorrhage 40

Hemorrhage Stroke Strokes Risk Factors 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

We investigated whether computed tomography perfusion (CTP) derived hypoperfusion index ratio correlates with the rate of hemorrhagic transformation.MethodsWe conducted a retrospective cohort analysis of a prospectively maintained patient database. female), 55 (19%) had hemorrhagic transformation. to 15.18; p=0.011).ConclusionIn

Hemorrhage 40

Hemorrhage Stroke Strokes 40

Frontiers in Cardiovascular Medicine

MAY 12, 2024

During the treatment, the patient received two sessions of external cardiopulmonary resuscitation (ECPR) as supportive care and experienced cerebral hemorrhage. Through a cautious anticoagulation therapy, not only was the ECMO support successfully maintained but also was further deterioration of cerebral hemorrhage effectively prevented.

Embolism 52

Embolism Hemorrhage Pulmonary Cardiac Arrest 52

Stroke Journal

FEBRUARY 1, 2024

Introduction:Intracerebral Hemorrhage (ICH) leads to high rates of morbidity and mortality. There was no association between BMI and ICH volume in patients with deep or lobar hemorrhage. Stroke, Volume 55, Issue Suppl_1 , Page AWMP81-AWMP81, February 1, 2024. Malnutrition is common in stroke patients and leads to worse outcomes.

Hemorrhage 40

Hemorrhage BMI Outcomes Coronary Artery Disease 40

Stroke Journal

FEBRUARY 1, 2024

Whether atrial cardiopathy is associated with the risk of intracranial hemorrhage in acute ischemic stroke (AIS) remains uncertain. Our primary outcomes included any intracranial hemorrhage (ICH) and symptomatic ICH (sICH) during follow-up. Our secondary outcome was ischemic stroke recurrence.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

We aimed to determine the prevalence, characteristics, and predictors of hemorrhagic foci in patients with RSSI.Methods:From a prospective, longitudinal study of RSSIs, we recruited patients who underwent multimodal MRI assessments at baseline and approximately one year after stroke onset. versus 75.7%, P = 0.001). versus 75.7%, P = 0.001).

Hemorrhage 40

Hemorrhage Stroke Strokes Circulation 40

Stroke Journal

FEBRUARY 1, 2024

Our study aims to describe the trends and outcomes of patients with Subarachnoid Hemorrhage (SAH) using a Nationwide Inpatient Sample (NIS) database.Methods:We examined the 2016-2020 NIS database, focusing on patients aged 18 years and older with a primary SAH discharge diagnosis. years with 72,650 (61.0%) being female. to COVID 5.6 (p=0.0006).

COVID-19 40

COVID-19 Hemorrhage Outcomes Inpatient 40

Dr. Smith's ECG Blog

MARCH 7, 2024

A young man presented with a gunshot wound to the right chest, with hemo-pneumothorax and hemorrhagic shock. He got a chest tube and intubation and massive transfusion and stabilized. CT of chest showed the bullet path through his right lung but nowhere near his heart. But he did get an EKG: What is this?

Hemorrhage 118

Hemorrhage Chest Pain Article AFIB 118

Science Daily - Stroke

NOVEMBER 20, 2023

A new study has revealed a new culprit in the formation of brain hemorrhages that does not involve injury to the blood vessels, as previously believed.

Hemorrhage 40

Hemorrhage Research 40

Stroke Journal

FEBRUARY 1, 2024

Project analysis began by identifying care opportunities.

Hemorrhage 40

Hemorrhage Stroke Strokes Best Practices 40

Stroke Journal

DECEMBER 21, 2023

FAST-MAG (Field Administration of Stroke Therapy-Magnesium) was a pragmatic clinical trial of magnesium sulfate administered prehospital for acute clinical stroke syndromes and included patients with intracerebral hemorrhage. Placebo patients had fewer serial neuroimaging studies available (123 [65.4%] versus 145 [75.1%];P=0.038).

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Science Daily - Stroke

MAY 22, 2023

Regular physical activity and exercise may reduce bleeding in individuals with intracerebral hemorrhage, a new study shows. The researchers emphasize the importance of physical activity to protect the brain.

Hemorrhage 40

Hemorrhage Exercise Research 40

Stroke Journal

FEBRUARY 1, 2024

In the EMS cohort, only patients seen between 8 am to 8 pm, corresponding to the operating hours of the MSU, were included. The target blood pressure goal was met much quicker in the MSU. Faster time metrics convey a hypothetical benefit towards improved patient outcomes.

Hemorrhage 40

Hemorrhage Blood Pressure Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Glial fibrillary acidic protein (GFAP) has been recently identified as a biomarker of intracerebral hemorrhage. GFAP values over 1000 pg/ml indicated a primary cerebral cause of coma with 100% certainty (hereof, 86% had intracranial hemorrhage).Conclusion:Increased

Hemorrhage 40

Hemorrhage Biomarkers Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Superficial (gray matter, vermis) cerebellar intracerebral hemorrhage (cICH) is associated with strictly lobar supratentorial cerebral microbleeds—a strong marker for cerebral amyloid angiopathy. Stroke, Volume 55, Issue Suppl_1 , Page AWP161-AWP161, February 1, 2024.

Hemorrhage 40

Hemorrhage Hypertension Risk Factors Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Spontaneous intracerebral hemorrhages (ICH) remains the most devastating form of stroke. SCUBA patient was matched with control ICH patient who received standard medical treatment at 1:1 ratio by variables (hematoma volume and laterality, intraventricular hemorrhage [IVH] with hydrocephalus, age, NIHSS, GCS).

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Stroke Journal

OCTOBER 30, 2024

BACKGROUND:Erythrolysis releases free Hb (hemoglobin), which is one of the most upstream and important molecules causing early brain injury and cerebral vasospasm after subarachnoid hemorrhage (SAH). mg/mL BSA, 30.1 mg/mL Hp (100%; a mixture of Hp1-1, Hp2-1, and Hp2-2), 50% Hp, 25% Hp, and 12.5% Hp solutions from 30 minutes postmodeling.

Hemorrhage 40

Hemorrhage Stroke Strokes 40