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Nature Reviews Cardiology, Published online: 04 April 2025; doi:10.1038/s41569-025-01146-x Hearttransplantation remains the optimal long-term treatment for appropriate patients with advanced heart failure. However, the donor heart shortage is a limiting factor, and the risk profile of transplant candidates is worsening.
Hearttransplantation is an effective treatment for end-stage heart disease, and postoperative patients' medication adherence is crucial for transplantation outcomes and long-term survival.
The Transplant Company recently announced that AlloSureis now commercially available for pediatric hearttransplant patients of all ages and patients who have received a simultaneous pancreas-kidney (SPK) transplant. 5 As with other organ transplants, the organs are at risk of rejection.
"Discover Advocate Children's Hospital's new pediatric hearttransplant program led by top doctors and certified by UNOS, in partnership with other top hospital
More than 4,500 hearttransplants were performed in the U.S. While the lifesaving operation improves the quality of life and longevity for most recipients, organ rejection remains a risk, with acute rejection occurring in up to 32% of recipients within the first year.
IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to hearttransplantation in children with end-stage heart failure. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.
(MedPage Today) -- The newborn that received the world's first partial hearttransplant in 2022 continued to do well a year later, according to a case report from the transplant team. Born with type A2 persistent truncus arteriosus and irreparable.
New York City-based NewYork-Presbyterian Morgan Stanley Children's Hospital performed the first "domino" hearttransplant on babies, according to an American Hospital Association report.
The world's first partial hearttransplant has achieved what researchers have spent more than a year hoping for—functioning valves and arteries that grow along with the young patient, as hypothesized by the pioneering team behind the procedure at Duke Health.
Advanced heart failure (AdvHF) can only be treated definitively by hearttransplantation (HTx), yet problems such right ventricle dysfunction (RVD), rejection, cardiac allograft vasculopathy (CAV), and primary graft dysfunction (PGD) are linked to a poor prognosis.
In 2024, Boston-based Tufts Medical Center performed 70 adult hearttransplants, breaking its 2023 record by nine and setting the New England region record for the second year in a row.
based Northwell Health has received approval from the state health department to open a hearttransplant center at Cohen Children's Medical Center in Queens. New Hyde Park, N.Y.-based
(MedPage Today) -- NBA champion and "Survivor" contestant Scot Pollard is "awake and feeling great" a day after a hearttransplant, his wife said Saturday on social media. Scot has a new heart!" Dawn Pollard posted Friday night on X, formerly.
In the United States, about 30-40% of donor hearts aren't considered for transplant due to inadequate function in the donor. This leads to a drop in the number of donated hearts that are available to be matched with someone who needs a hearttransplant.
Jon Kobashigawa, MD, of the Smidt Heart Institute at Cedars-Sinai, is an expert in hearttransplantation, heart failure, and other complex cardiac conditions. Kobashigawa was instrumental in expanding the Comprehensive Transplant Program at Cedars-Sinai , one of the largest transplant programs in the world. “Dr.
Oklahoma City-based Oklahoma Children's Hospital is the first in the state to open a pediatric hearttransplant program, ABC affiliate KOCO reported March 5.
"Discover the incredible story of Bert Janssen, the Dutch man who has lived with a donor heart for 39 years and 252 days, officially confirmed as the world's lo
Nearly a year after a newborn received the world's first partial hearttransplant, the transplanted valves and arteries are functioning well and growing along with the child's heart — a key measure of success in the procedure paving the way for future advancements.
Despite developments in circulating biomarker and imaging technology in the assessment of cardiovascular disease, the surveillance and diagnosis of hearttransplant rejection has continued to rely on histopathologic interpretation of the endomyocardial biopsy.
(MedPage Today) -- WASHINGTON -- Hearttransplant patient Eddie Garcia was "feeling like a million bucks" one day in the summer of 2021. He had just gotten back from a 3-mile walk, something he couldn't do prior to his transplant in 2020 -.
Michelle Kittleson, MD, PhD, provides insight into the potential impact of a new risk score for hearttransplant allocation as well as the need for more equitable cardiovascular care in the US.
Despite being a hearttransplantation candidate, she declined revascularization and sought alternative treatments for angina, dyspnea, and daily activity limitations. EECP may alleviate the need for hearttransplantation through its integration as a standard early intervention.
Pictured Left to Right: Members and students of the McGill Gene Editing Laboratory at The Texas Heart Institute in Houston, Texas: Fansen Meng, PhD, Xiao Li, PhD, James Martin, MD, PhD, Rich Li, PhD (back), Maggie Lim (undergraduate student at Rice University front), Yuka Morikawa, PhD, Ann Bromley.
Patients can develop de novo malignancies following orthotopic hearttransplantation. However, vascular tumors are not commonly described in this population.
"Vanderbilt Transplant Center sets world record with 174 hearttransplants in 2024, including pediatric procedures. Learn more about their achievements and adva
The risk of early heart failure after hearttransplantation is lower if the donor heart is stored in a so-called heart-in-a-box instead of in the usual cooler with ice.
Philadelphia-based University of Pennsylvania researchers found the number of hearttransplant emergency department visits increased with high admission rates but low in-hospital mortality rates.
The risk of early heart failure after hearttransplantation is lower if the donor heart is stored in a so-called heart-in-a-box instead of in the usual cooler with ice. This is according to a study by researchers at the University of Gothenburg.
Researchers at Atlanta-based Emory University developed artificial intelligence that they say improves the prediction of successful hearttransplants by 10%.
A 53-year-old woman with the dilated phase of hypertrophic cardiomyopathy underwent orthotopic hearttransplantation. The donor heart was evaluated as normal preoperatively without mitral regurgitation or the.
A heart pump device the size of an AA battery could help children in need of a hearttransplant wait at home rather than the hospital, Science Daily reported May 7.
By the end of the study cardiologists performed 10% fewer biopsies in the first year post-transplant and 40% fewer in the second year post-transplant despite an increase in follow-up biopsy rates for dual positives. Hanna , CareDx President and CEO.
Continuing significant advancements in the field of xenotransplantation, surgeon-scientists from the University of Maryland School of Medicine provided an extensive analysis on the second patient in the world to receive a genetically-modified pig organ.
The outcome of hearttransplantation is significantly affected by perioperative infections. Individualised immunosuppression strategies are essential to reduce the risk of such infections.
After struggling with heart failure for the first months of his life, doctors told his parents that Zeke would need a hearttransplant immediately. Within one day, our hearttransplant team performed the transplant surgery. Now Zane, 6, and Zeke, 5, are living lives the odds said were unlikely.
(MedPage Today) -- Public report cards for hearttransplant centers are under fire for not being meaningful -- potentially even misrepresentative of care quality -- as a given center's ratings may vary wildly from year to year, a study found.
Introduction Hearttransplantation (HT) is the only treatment option in children with heart failure secondary to cardiomyopathies and non-reparable congenital heart diseases. Rhythm disturbances that develop during follow-up can serve as early indicators of graft rejection and should be carefully evaluated.
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