Medical Xpress - Cardiology

FEBRUARY 12, 2024

Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from end-stage heart failure. While the procedure offers hope, the long-term outcomes for these young patients remain suboptimal due to allograft rejection and graft failure.

Transplant 71

Transplant Pediatrics Heart Transplant Heart Failure 71

DAIC

JANUARY 11, 2024

In organ transplantation, an extended criteria donor is defined as having perceived risk factors linked to poor subsequent outcomes, for example, those with age >55 or ischemic times exceeding 4 hours, which sometimes leads to rejection of the donor organ. utilizing the Paragonix SherpaPak CTS (p=0.022). “At

Transplant 111

Transplant Heart Transplant Technology Risk Factors 111

Cardiology Update

APRIL 25, 2024

The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/heart transplantation, HF hospitalizations, worsening HF, and KCCQ score changes. Among patients with HFpEF, those who received the shunt experienced poor outcomes than those who did not.

Heart Failure 98

Heart Failure Heart Transplant Transplant Research 98

Frontiers in Cardiovascular Medicine

MARCH 7, 2024

Background Belt electrode skeletal muscle electrical stimulation (B-SES) is an emerging therapy anticipated to yield more favorable outcomes than conventional neuromuscular electrical stimulation (NMES), owing to its larger stimulation area. However, information on its efficacy and safety in patients with heart failure remains limited.

Heart Failure 124

Heart Failure Obesity Heart Transplant Transplant 124

Circulation: Heart Failure

MARCH 8, 2024

Centers performing at least 1 heart transplant or left ventricular assist device were classified as ATCs. Patient characteristics, outcomes, and procedural volume were compared among 3 cohorts: admissions to non-ATCs, admissions to ATCs, and transfers to ATCs.

Heart Failure 40

Heart Failure Cardiogenic Shock Outcomes Cardiac Arrest 40

Frontiers in Cardiovascular Medicine

JANUARY 25, 2024

On the contrary, the use of transcatheter edge-to-edge mitral valve repair (TEER) has exponentially increased over the past decade, expanding its potential use even in patients on the heart transplantation waiting list.

Bicuspid/Mitral 69

Bicuspid/Mitral Heart Failure Heart Transplant Transplant 69

Open Heart

NOVEMBER 25, 2022

Cox models were created to investigate if UA was a significant predictor of adverse outcome where log1.1(UA) UA) was used to estimate the effect on outcome associated with a 10% increase in UA levels. Regression analyses were constructed to investigate the association between UA and haemodynamic variables.

Heart Failure 52

Heart Failure Outcomes Heart Transplant Artificial Heart 52

European Journal of Heart Failure

NOVEMBER 9, 2023

However, data on long-term outcome after upgrade to CRT are scarce. The primary composite endpoint included all-cause mortality, heart transplantation, or ventricular assist device implantation.

Outcomes 40

Outcomes Heart Failure Heart Transplant Transplant 40

Cardiology Update

JANUARY 22, 2024

[link] Patients with New York Heart Association (NYHA) class II or III heart failure, a left ventricular ejection fraction of 30% or less, and a QRS duration of 120 msec or more (or a paced QRS duration of 200 msec or more) were randomly assigned to receive either an ICD alone or a CRT defibrillator (CRT-D). to 0.92; P=0.002).

Heart Failure 115

Heart Failure Defibrillator Heart Transplant Transplant 115

Circulation

FEBRUARY 26, 2024

Cardiogenic shock continues to portend poor outcomes, conferring short-term mortality rates of 30% to 50% despite recent scientific advances. As a result, despite the association of advanced age with worse outcomes, focused strategies in the assessment and management of cardiogenic shock in this high-risk and growing population are lacking.

Cardiogenic Shock 74

Cardiogenic Shock Best Practices Heart Transplant Transplant 74

DAIC

JUNE 24, 2024

The Cordella platform is the first and only PA pressure-guided platform to offer comprehensive patient management using daily PA pressure and vital signs from home to guide therapeutic management and improve patient outcomes. This approval is very exciting and has the potential to transform care for HF patients.

Heart Failure 109

Heart Failure Reimbursement Heart Transplant Pulmonary 109

Circulation: Heart Failure

FEBRUARY 1, 2024

BACKGROUND:In 2018, an algorithm-based allocation system for heart transplantation (HT) was implemented in France. The cumulative incidence of waitlist mortality estimated with competing risk analysis and incidence of transplantation were compared between diagnosis groups. 1.51];P=0.19; RCM: HR, 1.19 [95% CI, 0.90–1.58];P=0.23;

Heart Failure 40

Heart Failure Congenital Heart Disease Congenital Cardiomyopathy 40

European Journal of Heart Failure

NOVEMBER 7, 2023

BNP, CMR-LVEF and SUVmax in FDG-PET: independent predictors of outcome in a contemporary cardiac sarcoidosis population remaining robust in subgroup subanalysis. Here, we describe baseline characteristics at presentation along with prognosis and predictors of outcome in a sizable and deeply phenotyped contemporary cohort of CS patients.

Sudden Cardiac Death 40

Sudden Cardiac Death Outcomes Heart Transplant Heart Failure 40

DAIC

FEBRUARY 21, 2024

Getty Images milla1cf Wed, 02/21/2024 - 19:10 February 21, 2024 — Ochsner Children's Hospital , ranked among the top hospitals in the nation for pediatric cardiology and congenital heart surgery, is raising awareness of the need for more pediatric-specific heart devices.

Pediatrics 105

Pediatrics Hospital Heart Failure Transplant 105

Circulation: Heart Failure

NOVEMBER 6, 2023

Circulation: Heart Failure, Ahead of Print.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Circulation 40

DAIC

MARCH 6, 2024

Food and Drug Adminstration (FDA) has approved DEFINITY (Perflutren Lipid Microsphere) as an ultrasound enhancing agent for use in pediatric patients with suboptimal echocardiograms, including those who have undergone heart transplant, or have Kawasaki disease or a congenital cardiovascular anomaly. 5 Kutty, S., et al (2016).

Pediatrics 105

Pediatrics Ultrasound Heart Transplant Echocardiogram 105

DAIC

DECEMBER 8, 2023

The DRAIN-HF study will evaluate the Aortix percutaneous mechanical circulatory support (pMCS) technology in patients with acute decompensated heart failure (ADHF) who are unresponsive to standard medical therapy. milla1cf Fri, 12/08/2023 - 08:07 December 8, 2023 — Procyrion, Inc. ,

Technology 113

Technology Heart Failure Heart Transplant Transplant 113

DAIC

APRIL 30, 2024

The highly positive outcomes observed in primate models highlight the potential of this strategy. Heart attacks typically kill millions of cardiac muscle cells, leaving the heart in a weakened state. Cardiovascular diseases are still among the top causes of death worldwide, and especially prevalent in developed countries.

Transplant 105

Transplant Heart Transplant Myocardial Infarction Heart Attack 105

All About Cardiovascular System and Disorders

FEBRUARY 24, 2024

A study published in JACC has compared the phenotypic expression and clinical outcomes in patients with arrhythmogenic cardiomyopathy [2]. Heart failure, heart transplantation and death by cardiac causes were more often seen in individuals with biventricular phenotype compared to isolated left or right ventricular phenotype.

Cardiomyopathy 52

Cardiomyopathy Chest Pain Heart Transplant Myocardial Infarction 52

DAIC

MARCH 13, 2024

We are pleased that CMS has provided coverage support for the confirmatory CardiAMP Heart Failure II study.” To my knowledge, no therapy has been proven to reduce mortality in these patients, and CardiAMP Heart Failure II has great potential to achieve this outcome by confirming our CardiAMP Heart Failure Trial results.”

CMS 111

CMS Heart Failure Reimbursement Quality of Life 111

DAIC

MAY 31, 2024

By the end of the study cardiologists performed 10% fewer biopsies in the first year post-transplant and 40% fewer in the second year post-transplant despite an increase in follow-up biopsy rates for dual positives. Hanna , CareDx President and CEO.

Heart Transplant 105

Heart Transplant Transplant Outcomes 105

Circulation

JANUARY 18, 2024

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) use to provide hemodynamic support for acute myocardial infarction has grown exponentially, is associated with poor outcomes, and is under active clinical investigation, yet the mechanistic effect of VA-ECMO on myocardial damage in acute myocardial infarction remains poorly understood.

Myocardial Infarction 45

Myocardial Infarction Heart Transplant Ischemia Transplant 45

Open Heart

MAY 25, 2022

Methods The primary outcome was the prevalence and incidence of TE in the patients with LVNC. The secondary outcome was the TE and mortality and heart transplantation rates between paediatric and adult patients with LVNC.

Heart Transplant 40

Heart Transplant Transplant Risk Factors Outcomes 40

European Journal of Heart Failure

OCTOBER 3, 2023

Characteristics of heart failure with improved ejection fraction (HFimpEF) patients and outcome comparison with heart failure with persistently reduced ejection fraction (pHFrEF). Nonetheless, these patients remain at risk for adverse outcome. HFimpEF patients had lower HF severity: left ventricular ejection fraction 44.0

Heart Failure 40

Heart Failure Exercise Laboratory Transplant 40

Society of Thoracic Surgeons - Technology

JANUARY 19, 2022

With her fellowship, Dr. Fiedler plans to learn skills and administrative approaches that will help her expand the heart transplant program at UW-Madison, where she currently serves as associate director of heart transplantation and mechanical circulatory support.

Cardiothoracic 52

Cardiothoracic Heart Transplant Allied Health Education 52

Circulation: Heart Failure

FEBRUARY 20, 2024

Circulation: Heart Failure, Ahead of Print. Background:Black heart transplant patients are at higher risk of acute rejection (AR) and death than White patients. The primary composite outcome occurred in 43% and 55% of Black patients at 1 and 2 years, compared with 23% and 27% in White patients,P<0.001.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Outcomes 40

Journal of the American Heart Association

JANUARY 3, 2024

BackgroundThe extent to which sex, racial, and ethnic groups receive advanced heart therapies equitably is unclear. Our primary outcome measures were the number of LVAD and HT procedures per 1000 adults with HFrEF. The main exposures were sex, race, ethnicity, and age.

Heart Transplant 45

Heart Transplant Transplant Heart Failure Inpatient 45

DAIC

APRIL 6, 2024

Gregg Stone, MD “When you examine the outcomes in patients with heart failure across a broad range of left ventricular ejection fraction, the Ventura interatrial shunt was extremely safe but did not improve outcomes compared with no treatment. There was a tremendous placebo effect,” he said.

Heart Failure 81

Heart Failure Quality of Life Outcomes Preserved Ejection Fraction 81

European Journal of Heart Failure

DECEMBER 13, 2023

Venn diagram of iron deficiency (ID) according to various definitions and associated outcomes. Abstract Aims There is uncertainty about the definition of iron deficiency (ID) and the association between ID and prognosis in patients with advanced heart failure. Non-scaled VENN diagram.

Heart Failure 40

Heart Failure Heart Transplant Transplant Tricuspid 40

DAIC

FEBRUARY 13, 2024

THE TEXAS HEART INSTITUTE 2024 milla1cf Tue, 02/13/2024 - 17:56 February 13, 2024 — Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from end-stage heart failure.

Transplant 111

Transplant Pediatrics Heart Transplant Research 111

Dr. Smith's ECG Blog

JANUARY 9, 2023

He was readmitted a few weeks later for a heart failure exacerbation, diuresed, and discharged again. The last information available is that the patient was undergoing heart transplant evaluation. She died before she could get a heart transplant. This gets drilled into them. Diagnostic of Massive OMI.

Chest Pain 52

Chest Pain Aneurysm STEMI Thrombosis 52

Dr. Sanjay Gupta

MARCH 6, 2022

If we are unable to build a relationship of trust with the patient then we are going to fail in achieving the best outcome for that patient and this is why engagement and empathy are so essential. Secondly all management should be ensconced in kindness, patience, connection and good communication.

Chronic Disease 40

Chronic Disease Quality of Life Heart Failure Nursing 40

Cardiology Update

APRIL 9, 2024

The percent change from baseline in fasting triglycerides (TG) at six months served as the primary outcome measure. The percent change from baseline in fasting TG at six months served as the primary outcome measure. Among patients with HFpEF, those who received the shunt experienced poor outcomes than those who did not.

Angina 52

Angina Myocardial Infarction Aortic valve Coronary Artery Disease 52

DAIC

APRIL 6, 2024

Gregg Stone, MD “When you examine the outcomes in patients with heart failure across a broad range of left ventricular ejection fraction, the Ventura interatrial shunt was extremely safe but did not improve outcomes compared with no treatment. There was a tremendous placebo effect,” he said.

Heart Failure 98

Heart Failure Quality of Life Preserved Ejection Fraction Hospital 98

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Program Designations Access and Publications (A&P) 1 Participant User File (PUF) 2 Task Force on Funded Research (TFR) 3 Special Projects 4 Adult Cardiac Surgery Database Lead Author Title Publication Date William Keeling 2 National Trends in Emergency Coronary Artery Bypass Grafting European Journal of Cardiothoracic Surgery October 2023 Jake (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52