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Two promising approaches in the treatment of myocardial infarction: stem cells and gene therapy

Frontiers in Cardiovascular Medicine

Although heart transplantation can replace the damaged heart, its clinical application and promotion are limited by the source of donor, expensive cost, immune rejection, and ethical problems. It has become an urgent task for clinical medicine to seek new and better treatment.

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Right Ventricular Function on Cardiovascular Magnetic Resonance Imaging and Long-Term Outcomes in Stable Heart Transplant Recipients

Circulation: Cardiovascular Imaging

BACKGROUND:In heart transplant recipients, right ventricular (RV) dysfunction may occur for a variety of reasons. Whether RV dysfunction in the stable phase after heart transplantation is associated with long-term adverse outcomes is unknown. years after heart transplantation were included.

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Using Stem Cell-derived Heart Muscle Cells to Advance Heart Regenerative Therapy

DAIC

Myocardial infarctions , commonly known as “heart attacks,” are on the rise, resulting in a significant number of deaths each year. Heart attacks typically kill millions of cardiac muscle cells, leaving the heart in a weakened state.

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Novel Role for Cardiolipin as a Target of Therapy to Mitigate Myocardial Injury Caused by Venoarterial Extracorporeal Membrane Oxygenation

Circulation

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) use to provide hemodynamic support for acute myocardial infarction has grown exponentially, is associated with poor outcomes, and is under active clinical investigation, yet the mechanistic effect of VA-ECMO on myocardial damage in acute myocardial infarction remains poorly understood.

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Phenotypes in Arrhythmogenic Cardiomyopathy

All About Cardiovascular System and Disorders

Heart failure, heart transplantation and death by cardiac causes were more often seen in individuals with biventricular phenotype compared to isolated left or right ventricular phenotype. Higher incidence of hot phases were noted in left ventricular and biventricular phenotypes.

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Highlights of ACC 2024

Cardiology Update

EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardial infarction (MI). Investigators assessed if empagliflozin could lower the risk of hospitalization for heart failure (HF) or death from cardiovascular disease (CVD). Here is our curated list of the top sessions.

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Heart Pump Improves Survival After Severe Heart Attacks

DAIC

Previous trials evaluating the potential benefits of this and other heart pumps for cardiogenic shock have had mixed results. of those who received the Impella pump had died at six months after randomization; there was a 13 percentage point absolute reduction in the rate of death, the study’s primary endpoint, in favor of the heart pump.