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Recognized causes include drugs, myocardial ischemia, and hypoxia. Its association with orthotopic hearttransplantation (OHT) is not known. Atrial standstill is a rare condition characterized by the absence of electrical and mechanical activity of the atria.
End-stage ischemic heart disease necessitates hearttransplantation, and emerging cell therapy presents a promising solution to address donor scarcity. Disruption of gut microbiota significantly influences various diseases and treatments, including transplantation.
BACKGROUND:Cardiolipin is a mitochondrial-specific phospholipid that maintains integrity of the electron transport chain (ETC) and plays a central role in myocardial ischemia/reperfusion injury. Circulation, Ahead of Print. Tafazzin is an enzyme that is required for cardiolipin maturation.
At present, the main methods to treat ischemic heart disease are drug therapy, intervention and operation. These methods only alleviate symptoms of heart failure and myocardial ischemia and improve patients' quality of life by partially restoring myocardial reperfusion.
Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. This may result in ischemia (lack of oxygen to the heart muscle), causing parts of the heart to weaken and enlarge.
of those who received the Impella pump had died at six months after randomization; there was a 13 percentage point absolute reduction in the rate of death, the study’s primary endpoint, in favor of the heart pump. Among 355 patients who were included in the analysis, 58.5% of those who received standard care alone and 45.8%
He was readmitted a few weeks later for a heart failure exacerbation, diuresed, and discharged again. The last information available is that the patient was undergoing hearttransplant evaluation. She died before she could get a hearttransplant. They just could not believe that a young woman could have an OMI.
As hearttransplantation continues to be the gold standard therapy for end-stage heart failure, the imbalance between the supply of hearts, and the demand for them, continues to get worse. Notably, ex vivo perfusion has facilitated the donation of DCD hearts and improved the success of transplantation.
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