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Preserving the future of heart transplantation

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 04 April 2025; doi:10.1038/s41569-025-01146-x Heart transplantation remains the optimal long-term treatment for appropriate patients with advanced heart failure. However, the donor heart shortage is a limiting factor, and the risk profile of transplant candidates is worsening.

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The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experience”

Frontiers in Cardiovascular Medicine

IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heart failure. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.

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Better transplantations with 'heart-in-a-box': Study finds method reduces early heart failure risk

Medical Xpress - Cardiology

The risk of early heart failure after heart transplantation is lower if the donor heart is stored in a so-called heart-in-a-box instead of in the usual cooler with ice. This is according to a study by researchers at the University of Gothenburg.

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Too Ill for Typical Transplants, Woman Gets a Pig Kidney and Heart Pump Instead

Med Page Today

(MedPage Today) -- A 54-year-old New Jersey woman has become the first-ever patient to undergo combined mechanical heart pump and gene-edited pig kidney transplant surgery, doctors announced. The patient, Lisa Pisano, had heart failure and end.

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Cedars-Sinai Cardiologist Leads the American Society of Transplantation

DAIC

Jon Kobashigawa, MD, of the Smidt Heart Institute at Cedars-Sinai, is an expert in heart transplantation, heart failure, and other complex cardiac conditions. Kobashigawa was instrumental in expanding the Comprehensive Transplant Program at Cedars-Sinai , one of the largest transplant programs in the world. “Dr.

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Novel device therapies in heart failure: focus on patient selection

Frontiers in Cardiovascular Medicine

The increasing prevalence of heart failure (HF) has led to advancements in therapeutic strategies, including the development of new pharmacological treatments and the expansion of guideline recommendations across the spectrum of left ventricular ejection fractions.

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RELIEVE-HF: Interatrial shunt in patients with heart failure

Cardiology Update

RELIEVE-HF investigators evaluated the efficacy and safety of the V-wave interatrial shunt system in patients with heart failure. The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/heart transplantation, HF hospitalizations, worsening HF, and KCCQ score changes. Atlanta, GA.