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Tenax Therapeutics Announces New U.S. Patent Covering the Use of Levosimendan in Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)

DAIC

Initially discovered and developed by Orion Corporation in Finland, intravenous levosimendan is approved in 60 countries outside the United States for use in hospitalized patients with acutely decompensated heart failure. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,

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Chronic Thromboembolic Pulmonary Hypertension: the therapeutic assessment

Frontiers in Cardiovascular Medicine

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure.

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Heart Failure in Zero Gravity—External Constraint and Cardiac Hemodynamics

JAMA Cardiology

In this case series study, pulmonary artery systolic, diastolic, and mean pressures of 2 participants with obesity and heart failure with preserved ejection fraction were measured at zero gravity during parabolic flight to assess the effect of external constraint on left ventricular filling pressures.

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Dapagliflozin and Right Ventricular Pulmonary Vasculature in HFpEF

JAMA Cardiology

This randomized clinical trial investigates the effect of dapagliflozin on right ventricular performance and vascular load during exertion in heart failure with preserved ejection fraction (HFpEF).

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Expanding the Use of Invasive Implanted Hemodynamic Monitoring in Pediatric Patients: Exercise Hemodynamics, Pulmonary Hypertension, and Heart Failure

American College of Cardiology

What is the safety and utility of invasive implanted hemodynamic monitoring (IHM) using the CardioMEMS™ HF System in pediatric patients with heart failure (HF) and pulmonary hypertension (PH)?

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Clinical characteristics and mortality risk factors in pediatric hypertrophic, restrictive, and rapidly progressive hypertrophic cardiomyopathy: a retrospective cohort study with follow-up

Frontiers in Cardiovascular Medicine

Infection (75.47%, 160/212) and heart failure (51.42%, 109/212) were common comorbidities. The independent risk factors for mortality included left ventricular ejection fraction (LVEF), pulmonary hypertension, and low-density lipoprotein (LDL) levels (P<0.05).

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Decongestion in acute heart failure: Is it time to change diuretic‐centred paradigm?

European Journal of Heart Failure

Guideline directed medical therapy (GDMT)-centred decongestion in heart failure (HF). Abstract Congestion is a common cause of clinical deterioration and the most common clinical presentation at admission in acute heart failure (HF).