Cardiovascular Ultrasound

MARCH 3, 2024

Heart failure with preserved ejection fraction (HFpEF) represents a significant proportion of heart failure cases. Accurate diagnosis is challenging due to the heterogeneous nature of the disease and limitatio.

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HeartRhythm

SEPTEMBER 4, 2024

Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) are comorbid conditions that are increasingly prevalent and have a high socioeconomic burden. This article discusses their shared pathophysiology, focusing on the triad of hypertension, obesity, and aging.We

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Preserved Ejection Fraction Atrial Fibrillation Heart Failure Quality of Life 40

Science Daily - Heart Disease

AUGUST 1, 2024

A new small study has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).

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Heart Failure Preserved Ejection Fraction Obesity 115

American College of Cardiology

APRIL 6, 2024

The goal of the STEP-HFpEF DM trial was to compare the safety and efficacy of semaglutide among patients with obesity-related heart failure with preserved ejection fraction (HFpEF) and type 2 diabetes mellitus (DM).

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Preserved Ejection Fraction Heart Failure Obesity Diabetes 69

Medical Xpress - Cardiology

JULY 29, 2024

A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

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Preserved Ejection Fraction Heart Failure Research Hospital 111

Science Daily - Heart Disease

SEPTEMBER 2, 2024

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial.

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American College of Cardiology

JULY 8, 2024

The goal of the PARAGON-HF trial was to evaluate the neprilysin-angiotension receptor inhibitor sacubitril/valsartan among patients with heart failure with preserved ejection fraction (HFpEF).

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Preserved Ejection Fraction Heart Failure Outcomes Article 56

Science Daily - Heart Disease

JULY 29, 2024

A novel study co-authored by a heart failure cardiologist demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

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Preserved Ejection Fraction Heart Failure 95

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Heart failure with preserved ejection fraction (HFpEF) is the largest unmet clinical need in cardiovascular medicine. Despite decades of research, the treatment option for HFpEF is still limited, indicating our ongoing incomplete understanding on the underlying molecular mechanisms.

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Preserved Ejection Fraction Heart Failure Biomarkers Cardiovascular Disease 59

American Heart News - Heart News

JULY 24, 2024

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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Preserved Ejection Fraction Heart Failure Research 98

Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

Heart failure with preserved ejection fraction (HFpEF) is a widespread syndrome with limited therapeutic options and poorly understood immune pathophysiology.

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Preserved Ejection Fraction Heart Failure Obesity Ablation 75

European Journal of Heart Failure

APRIL 17, 2024

HFpEF, heart failure with preserved ejection fraction; MR, mitral valve regurgitation. Abstract Mitral regurgitation (MR) is highly prevalent among patients with heart failure and preserved ejection fraction (HFpEF).

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Preserved Ejection Fraction Bicuspid/Mitral Heart Failure Pulmonary 40

HeartRhythm

APRIL 30, 2024

The efficacy of catheter ablation as a treatment approach for patients with concurrent atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) has been inadequately investigated.

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Frontiers in Cardiovascular Medicine

JANUARY 28, 2024

Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) have emerged as major age-related epidemics within cardiology. Indeed, these two conditions are commonly found in the same individual, so much so that AF has been used in proposed diagnostic criteria for HFpEF.

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Preserved Ejection Fraction Heart Failure Atrial Fibrillation Electrophysiology 59

European Journal of Heart Failure

FEBRUARY 18, 2024

Global longitudinal strain (GLS) and clinical outcomes in heart failure with preserved ejection fraction (HFpEF). Almost 47% of patients with HFpEF had evidence of left ventricular (LV) subclinical dysfunction, defined as absolute LV GLS 0.1).

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Preserved Ejection Fraction Heart Failure Hospital Outcomes 40

Heart BMJ

FEBRUARY 12, 2024

Objective Heart failure with preserved ejection fraction (HFpEF) is a common heterogeneous syndrome that remains imprecisely defined and consequently has limited treatment options and poor outcomes. Patients with an ejection fraction between 40% and 49% will be limited to no more than 25% of the cohort.

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European Journal of Heart Failure

DECEMBER 13, 2023

BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. ABSTRACT Aim Chronic obstructive pulmonary disease (COPD) is common in heart failure with a mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and is associated with worse outcomes.

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Preserved Ejection Fraction Heart Failure Pulmonary Quality of Life 75

JAMA Cardiology

APRIL 23, 2024

This systematic review and meta-analysis investigates the efficacy of catheter ablation compared with rate or rhythm control among patients with atrial fibrillation and heart failure.

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Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 72

Frontiers in Cardiovascular Medicine

MARCH 3, 2024

Introduction Heart failure with preserved ejection fraction (HFpEF) is a complex disease process influenced by metabolic disorders, systemic inflammation, myocardial fibrosis, and microvascular dysfunction.

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Preserved Ejection Fraction Biomarkers Heart Failure 64

Circulation: Heart Failure

OCTOBER 23, 2023

Circulation: Heart Failure, Volume 16, Issue 11 , Page e010802, November 1, 2023. Heart failure with preserved ejection fraction (HFpEF) has become the leading form of heart failure worldwide, particularly among elderly patient populations.

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HeartRhythm

APRIL 14, 2024

The benefit of catheter ablation in patients with atrial fibrillation (AF) for patients with heart failure with preserved ejection fraction (HFpEF) remains uncertain.

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Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 40

European Journal of Heart Failure

DECEMBER 7, 2023

ABSTRACT Background Left atrial (LA) myopathy is increasingly recognized as an important phenotypic trait in heart failure (HF) with preserved ejection fraction (HFpEF). 2.92, p = 0.01). Further study is required to define optimal strategies to treat and prevent biatrial myopathy in HFpEF.

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JAMA Cardiology

JUNE 30, 2023

This post hoc analysis of a randomized clinical trial evaluates the safety and efficacy of empagliflozin in patients with heart failure and preserved ejection fraction who are taking diuretics.

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Science Daily - Heart Disease

MAY 30, 2024

A mouse study of heart failure with preserved ejection fraction (HFpEF) found male-female differences at the cellular level. The findings could have implications for how HFpEF is treated in women compared to men.

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HeartRhythm

APRIL 30, 2024

However, it is unknown whether these patterns hold for persistent AF among patients with heart failure with preserved ejection fraction (HFpEF). Studies have suggested that early atrial fibrillation (AF) ablation is associated with improved outcomes. The majority of these studies evaluated paroxysmal AF cases.

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Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 40

Circulation: Heart Failure

OCTOBER 23, 2023

Circulation: Heart Failure, Volume 16, Issue 11 , Page e010633, November 1, 2023. BACKGROUND:Heart failure with preserved ejection fraction is associated with significant functional limitations, yet treatments for improving exercise performance have been elusive.

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Preserved Ejection Fraction Heart Failure Biomarkers Exercise 40

HeartRhythm

APRIL 30, 2024

Patients with heart failure with preserved ejection fraction (HFpEF) have many comorbidities including SND, but the optimal treatment approach for HFpEF with SND is uncertain. Guidelines recommend permanent pacemaker (PPM) implantation in patients with sinus node dysfunction (SND) to improve quality of life.

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Preserved Ejection Fraction Heart Failure Quality of Life Medicare 40

European Journal of Heart Failure

OCTOBER 30, 2023

In patients with heart failure with preserved ejection fraction (HFpEF), abnormal global longitudinal strain (GLS) is a strong predictor for clinical events and can help identity patients who are at risk for future decline in left ventricular ejection fraction (LVEF). After a median follow-up of 4.6 years,

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Preserved Ejection Fraction Heart Failure Outcomes Hospital 40

Science Daily - Heart Disease

FEBRUARY 21, 2024

In ambulatory women ages 63-99 years, higher amounts of usual daily light and moderate intensity activities were associated with lower risk of developing heart failure with preserved ejection fraction independent of demographic and clinical factors associated with heart failure risk.

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HeartRhythm

APRIL 30, 2024

The data on comparison of parameters of diastolic dysfunction (DD) on transthoracic echocardiogram (TTE) according to the progressive stages of AF in patients with coexisting heart failure with preserved ejection fraction (HFpEF) are limited.

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Preserved Ejection Fraction Heart Failure Echocardiogram Atrial Fibrillation 40

European Journal of Heart Failure

DECEMBER 28, 2023

Abstract Aims Preventive strategies for heart failure (HF) with preserved ejection fraction (HFpEF) include pharmacotherapies and lifestyle modifications. Thus, we evaluated the association between CRF and HFpEF incidence.

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Preserved Ejection Fraction Heart Failure Myocardial Infarction Article 40

Medical Xpress - Cardiology

JULY 24, 2024

Increasing ketone supply to the heart in mice with heart failure with preserved ejection fraction (HFpEF) allowed their hearts to utilize more ketones and produce more energy, according to preliminary research presented today at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2024.

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Preserved Ejection Fraction Heart Failure Innovation Research 75

European Journal of Heart Failure

DECEMBER 7, 2023

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Obesity was associated with more first and recurrent heart failure events.

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Journal of the American Heart Association

FEBRUARY 14, 2024

Pathological increases in renal sympathetic nerve activity contribute to the pathogenesis of heart failure with preserved ejection fraction (HFpEF).We BackgroundThe renal sympathetic nervous system modulates systemic blood pressure, cardiac performance, and renal function.

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Preserved Ejection Fraction Heart Failure Blood Pressure Biomarkers 40

HeartRhythm

APRIL 30, 2024

Left atrial and pulmonary artery pressure (PAP) elevation can reflect severity and dynamic status of heart failure (HF) in HF with preserved ejection fraction (pEF). Atrial fibrillation (AF) worsens HFpEF progression and pump failure, but catheter ablation can restore rhythm control in this population.

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Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 40

Journal of the American Heart Association

DECEMBER 29, 2023

Journal of the American Heart Association, Ahead of Print. BackgroundHeart failure with preserved ejection fraction ≥50% is prevalent with few evidence‐based therapies. points, whereas usual care worsened by 6.9 points,P<0.001).

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Preserved Ejection Fraction Heart Failure Quality of Life Echocardiogram 40

Heart BMJ

FEBRUARY 23, 2024

Objective The heterogeneous pathophysiology of the diverse heart failure with preserved ejection fraction (HFpEF) phenotypes needs to be examined. We aim to assess differences in the biomarkers among the phenotypes of HFpEF and investigate its multifactorial pathophysiology.

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Preserved Ejection Fraction Heart Failure Biomarkers Hypertension 40