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This secondary analysis of the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients With HeartFailure (FINEARTS-HF) randomized clinical trial evaluates the effect of finerenone on outpatient worsening heartfailure events requiring oral diuretic intensification among patients with heartfailure with mildly reduced or (..)
This proof-of-principle study investigates the association between tissue sodium content, assessed by MRI, and HF-related baseline parameters in an outpatient cohort of patients with chronic heartfailure, including those with reduced ejectionfraction (HFrEF), mildly reduced ejectionfraction (HFmrEF), and preservedejectionfraction (HFpEF).Methods
Heartfailure with preservedejectionfraction (HFpEF) is a common concern in the medical field due to its prevalence in an ageing western population. HFpEF is associated with significant morbidity and mortality not dissimilar to heartfailure (HF) with reduced ejectionfraction.
The trial, called RELIEVE-HF , is the first randomized placebo-procedure controlled trial of interatrial shunting that included patients with both major types of heartfailure : heartfailure with reduced ejectionfraction (HFrEF) and heartfailure with preservedejectionfraction (HFpEF).
The trial, called RELIEVE-HF , is the first randomized placebo-procedure controlled trial of interatrial shunting that included patients with both major types of heartfailure : heartfailure with reduced ejectionfraction (HFrEF) and heartfailure with preservedejectionfraction (HFpEF).
Introduction The diagnostic and therapeutic arsenal for heartfailure with preservedejection (HFpEF) has expanded. With novel therapies (eg, sodium-glucose co-transporter 2 inhibitors) and firmer recommendations to optimise non-cardiac comorbidities, it is unclear if outpatient HFpEF models can adequately deliver this.
The primary effectiveness endpoint was a composite of death, heart transplant/left ventricular assist device (LVAD) implantation, HF hospitalization, outpatient HF worsening, and quality of life. HFpEF is HF with preservedejectionfraction in which pressure builds up in the heart and lungs due to a stiffened left ventricle.
Introduction This study aimed to evaluate the use and dose of loop diuretics (LDs) across the entire ejectionfraction (EF) spectrum in a large, ‘real-world’ cohort of chronic heartfailure (HF) patients. Results In this cohort, 8512 (82.1%) patients used diuretics, of which 8179 (96.1%) used LDs.
HFpEF, heartfailure with preservedejectionfraction. Whether left ventricular size predicts functional capacity in patients with heartfailure with preservedejectionfraction (HFpEF) is unclear.
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