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Background Heartfailure with preserved ejection fraction is a recognised outcome in patients with myocardial infarction, although heartfailure with reduced ejection fraction is more common. fold higher risk of heartfailure with preserved ejection fraction (95% CI 1.30 m/s had a 2.10-fold
BackgroundHeart failure (HF) is a leading cause of morbidity and mortality worldwide. Various factors can exacerbate disease progression in patients with HF and negatively impact treatment outcomes. ConclusionThe prevalence of poor HF treatment outcomes in Ethiopia was found to be high.
Chronic heartfailure (CHF) combined with depression represents a significant clinical challenge due to the mutual exacerbation of physical and psychological symptoms. Outcomes were assessed by evaluating the clinical efficacy, cardiac function, inflammatory markers, depressive symptoms, and quality of life.
Implantation of an intra-aortic balloon pump (IABP) did not improve 60-day survival or bridge to heart replacement (HRT) therapies in patients with heartfailure-cardiogenic shock (HF-CS) compared to standard care, according to a study presented during a Featured Clinical Research session at ACC.25
Care for survivors after an acute attack of COVID-19 should include paying close attention to cardiovascular health and disease.Systematic Review RegistrationPROSPERO [CRD42022353965].
Association of clonal haematopoiesis with heartfailure incidence and outcomes: A systematic review and meta-analysis. Clonal haematopoiesis and heartfailure: a meta-analysis. CH, clonal haematopoiesis; CI, confidence interval; HF, heartfailure.
Heartfailure is a growing health-care concern affecting tens of millions of individuals globally. Although traditional therapeutic strategies have focused on reducing the risk for hospitalization and mortality, the importance of patient-reported outcomes (PROs) in patients with heartfailure is increasingly being recognized.
(MedPage Today) -- How patients with acute decompensated heartfailure (HF) perceived the financial challenges of their healthcare played out in their health outcomes, despite receiving life-prolonging medications, a prospective study from China.
Despite proven benefits in reducing morbidity and mortality, many heartfailure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). ESC HeartFailure 2024; 11 : 560–569. The post Digital Consults to Enhance HeartFailure Treatment: The ADMINISTER Trial appeared first on Cardiology Update.
Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heartfailure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes.
Background Atrial arrhythmias (AA) and heartfailure (HF) are major causes of hospitalisation in adult congenital heart disease (ACHD). Dates of first AA and HF presentations were documented, and outcomes of RFA, including acute and long-term success, were assessed.
The association between ACC and clinical outcomes in HF patients was analyzed using Cox proportional hazards regression and restricted cubic spline models.ResultsA total of 4,737 heartfailure patients were included. Patients were stratified into three groups based on ACC levels.
Heartfailure (HF) is a highly prevalent long-term condition, with variation in services and resources across the UK. Studies are needed to determine if they are adequately resourced to meet population needs and improve patient outcomes. Eighty-five responses describing community HF services were received.
AimThe association between red cell distribution widthalbumin ratio (RAR) and the risk of all-cause mortality in intensive care unit (ICU) patients with heartfailure remains uncertain. database was utilized for the analysis of ICU patients with heartfailure.
RELIEVE-HF investigators evaluated the efficacy and safety of the V-wave interatrial shunt system in patients with heartfailure. The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/heart transplantation, HF hospitalizations, worsening HF, and KCCQ score changes. April 6, 2024.
Heartfailure (HF) is one of the significant complications in patients with myocardial infarction (MI), leading to increased risk for cardiovascular morbidity and mortality. 2 Therefore, early identification of HF in high-risk populations, particularly post-MI, is essential for improving outcomes.
(‘Reprieve’), a development stage company focused on pioneering an intelligent approach to acute decompensated heartfailure (ADHF) treatment, today highlighted the publication of TREAT-AHF study results in JACC: HeartFailure. Heartfailure (HF) is a leading cause of hospitalization in the United States.
This multicenter secondary analysis of the FINEARTS-HF randomized clinical trial examines the treatment effect of finerenone, relative to placebo, on clinical outcomes based on postrandomization potassium levels.
ObjectiveThis network meta-analysis was to compare the efficacy of different drugs on cardiac function, renal function, and clinical outcomes in patients with acute heartfailure (AHF) accompanied by renal dysfunction.MethodsPubMed, EMBASE, Cochrane Library, and Web of Science were searched to screen all clinical trials of AHF between January 1st 2001 (..)
Eli Lilly's tirzepatide showed a 38% reduction in heartfailureoutcomes and improved symptoms in adults with HFpEF and obesity in the phase 3 SUMMIT trial.
recently announced that Digitiva, a non-invasive digital health solution for heartfailure management, has been listed with the U.S. a smartphone app designed for heartfailure patients and built on the Welldoc, Inc. tim.hodson Thu, 09/19/2024 - 09:42 Sept. 18, 2024 – Astellas Pharma Inc.
IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heartfailure. The primary outcome was survival at the follow-up evaluation.
Background Iron deficiency (ID) is a highly prevalent comorbidity in patients with chronic and acute heartfailure and is associated with worse clinical outcomes. We aimed to evaluate the prevalence and clinical characteristics of ID and its association with in-hospital congestion and postdischarge outcomes.
milla1cf Mon, 02/26/2024 - 12:40 February 26, 2024 — More than 6 million Americans live with heartfailure , and about half have an enlarged left ventricle, which causes stress on the heart and less blood pumped with each heartbeat. Patients may experience trouble breathing and fatigue, and at times require hospitalization.
Heartfailure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. Empagliflozin (EMPA) improves cardiovascular outcomes in HFpEF patients, but the underlying mec.
IntroductionHeart failure (HF) with improved ejection fraction (HFimpEF) was shown to be related with improved outcome but increase of left ventricular ejection fraction (LVEF) in patients without HF is of less known clinical significance.
Background Heartfailure (HF) is a leading cause of morbidity and mortality worldwide. Our findings suggest that monitoring and managing SUA could be crucial in improving patient with HF outcomes. Serum uric acid (SUA), a product of purine metabolism, has been implicated in HF progression.
mtaschetta-millane Wed, 07/31/2024 - 06:00 July 31, 2024 — A novel study co-authored by a heartfailure cardiologist at University Hospitals Harrington Heart & Vascular Institute, demonstrates the effectiveness of a newly developed scoring system in identifying patients with HeartFailure with Preserved Ejection Fraction (HFpEF).
Background Belt electrode skeletal muscle electrical stimulation (B-SES) is an emerging therapy anticipated to yield more favorable outcomes than conventional neuromuscular electrical stimulation (NMES), owing to its larger stimulation area. However, information on its efficacy and safety in patients with heartfailure remains limited.
Baseline characteristics for the vericiguat global study in participants with chronic heartfailure (VICTOR) trial. of participants had no prior hospitalization for heartfailure. Conclusion The VICTOR trial enrolled the most optimally treated population in a phase III heartfailure trial. beta-blockers, 94.3%
Matthew Segar co-authored a study in JACC HeartFailure led by his research and residency mentor, University of Texas Southwestern Medical Center's Dr. Ambarish Pandey , that utilized a machine learning-based-approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heartfailure (ADHF).
milla1cf Tue, 05/28/2024 - 07:00 May 28, 2024 — Yoga focused on breathing, meditation, and relaxation is linked with symptom improvement in patients with heartfailure, according to research presented at HeartFailure 2024 , a scientific congress of the European Society of Cardiology (ESC).
The researchers looked at data from 4,286 people -- out of a total of 17,605 from the landmark Semaglutide and Cardiovascular Outcomes (SELECT) trial who were randomly assigned either semaglutide or a placebo -- who were followed up over an average of more than three years.
Circulation: HeartFailure, Ahead of Print. The genotype-phenotype interdependence causes unpredictable phenotypic penetrance that results in a variety of signs and symptoms and patient outcomes. About 3% to 4% of patients with African ancestry carry this genetic predisposition to develop signs and symptoms of hATTR-CA.
However, whether it delivers comparable efficacy with different capture sites in heartfailure (HF) patients remains unclear. Left bundle branch pacing (LBBP) is a novel physiological pacing modality.
The primary outcome measure for the study is change in six-minute walk distance from Baseline to Week 12. Initially discovered and developed by Orion Corporation in Finland, intravenous levosimendan is approved in 60 countries outside the United States for use in hospitalized patients with acutely decompensated heartfailure.
(MedPage Today) -- Breathing machines with adaptive servo-ventilation (ASV) did not improve survival or other clinical outcomes in patients with heartfailure (HF) and reduced ejection fraction and sleep-disordered breathing, the phase III ADVENT.
Abstract In patients with heartfailure, neurohumoral activation leads to increased renal sodium avidity across the entire renal tubules, resulting in a positive sodium and water balance, leading to decompensated heartfailure requiring intravenous diuretics.
ABSTRACT Aims Heartfailureoutcomes remain poor despite advances in therapy. The European Society of Cardiology HeartFailure III Registry (ESC HF III Registry) aims to characterize HF clinical features and outcomes and to assess implementation of guideline-recommended therapy in Europe and other ESC affiliated countries.
BackgroundInfective endocarditis (IE) is still a fatal disease, and given its rarity, ongoing updates to patient characteristics and outcomes of IE are essential for providing precision diagnoses and effective treatments. The inhospital mortality rate was 14.5%, which significantly increased from 14.1% in 2016 to 15.4%
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