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Background Heartfailure with preservedejectionfraction is a recognised outcome in patients with myocardialinfarction, although heartfailure with reduced ejectionfraction is more common. fold higher risk of heartfailure with preservedejectionfraction (95% CI 1.30
Heartfailure (HF) is one of the significant complications in patients with myocardialinfarction (MI), leading to increased risk for cardiovascular morbidity and mortality. 2 However, mortality rate is greater in HF cases developing >3 days following MI compared with less than or equal to 3 days after MI.
Beta-blockers are commonly used in patients with heartfailure and mildly reduced or preservedejectionfraction (HFmrEF/HFpEF). Methods and results We pooled individual patient data from four large HFmrEF/HFpEF trials (I-Preserve, TOPCAT, PARAGON-HF, and DELIVER).
Abstract Aims Preventive strategies for heartfailure (HF) with preservedejectionfraction (HFpEF) include pharmacotherapies and lifestyle modifications. All had no evidence of HF or myocardialinfarction prior to completion of the ETT. years and 43,179 women; mean age 55.0±8.9 years) year apart.
The secondary outcomes were composite major adverse cardiac events (MACE) (study defined), myocardialinfarction (MI), stroke, cardiac death, sudden death, the development of symptoms, heartfailure hospitalisations and major bleeding. The primary outcome was all-cause mortality. to 1.1), I 2 =31%, p=0.09).
BACKGROUND:Apparent treatment-resistant hypertension (aTRH) is prevalent and associated with adverse outcomes in heartfailure with mildly reduced or preservedejectionfraction. Less is known about the potential role of sodium-glucose co-transporter 2 inhibition in this high-risk population.
Circulation: HeartFailure, Volume 17, Issue 12 , Page e011629, December 1, 2024. Spironolactone, a steroidal mineralocorticoid receptor antagonist (MRA), has been used to treat patients with heartfailure (HF) for more than half a century. The use of MRAs has been limited due to excessive concern about hyperkalemia.
ObjectiveTo investigate the therapeutic effect of Vericiguat combined with “new quadruple” drugs on patients with heartfailure (HF).MethodsFrom Patients diagnosed with preservedejectionfraction (HFpEF) were treated with Vericiguat combined with “ARNI, BB, SGLT2i” therapy.
ET Main Tent (Hall B1) - A Double-blind, Randomized Placebo Procedure-controlled Trial of an Interatrial Shunt in Patients with HFrEF and HFpEF: Principal Results From the RELIEVE-HF Trial - Empagliflozin After Acute MyocardialInfarction: Results of the EMPACT-MI Trial - CSL112 (Apolipoprotein A-I) Infusions and Cardiovascular Outcomes in Patients (..)
EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardialinfarction (MI). Investigators assessed if empagliflozin could lower the risk of hospitalization for heartfailure (HF) or death from cardiovascular disease (CVD). Here is our curated list of the top sessions.
There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heartfailure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] Is the obesity paradox a real phenomenon?
BackgroundThe mortality of patients with acute myocardialinfarction (MI) raised rapidly in last decade and obesity are becoming the major cause to CAD progression, thus inducing heartfailurepreservedejectionfraction (HFpEF).
Emerging Risk Factors: Non-traditional factors such as the microbiome, pollution, and somatic mutations are increasingly linked to “SMuRFless” myocardialinfarction (MI) cases. Biomarker-Based HF Prediction: Combined biomarker and imaging assessments provide the highest accuracy in predicting heartfailure risk.
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