Circulation

JANUARY 18, 2024

BACKGROUND:Cardiolipin is a mitochondrial-specific phospholipid that maintains integrity of the electron transport chain (ETC) and plays a central role in myocardial ischemia/reperfusion injury. Tafazzin is an enzyme that is required for cardiolipin maturation.

Myocardial Infarction 45

Myocardial Infarction Heart Transplant Ischemia Transplant 45

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

EMS 12-Lead

MAY 20, 2022

There is broad subendocardial ischemia as demonstrated by STE aVR with concomitant STD that almost appears appropriately maximal in Leads II and V5. There is LBBB-like morphology with persistent patterns of subendocardial ischemia. This is the initial ECG: The QRS is widened with a regular cadence, and there are no discernable P waves.

Cardiomyopathy 52

Cardiomyopathy Ischemia STEMI Coronary Angiogram 52

Dr. Smith's ECG Blog

FEBRUARY 15, 2018

100% occluded RCA with TIMI 0 flow Post drug-eluting stent placement with TIMI 3 flow While in the cath lab, she transiently developed complete heart block and became hypotensive requiring transvenous pacemaker placement and transient pressors. Peak troponin T was 3.00 ng/mL (highly elevated). Post-cath ECG with resolution of acute changes.

Chest Pain 52

Chest Pain Critical Care Article Pacemaker 52

Frontiers in Cardiovascular Medicine

FEBRUARY 19, 2025

At present, the main methods to treat ischemic heart disease are drug therapy, intervention and operation. These methods only alleviate symptoms of heart failure and myocardial ischemia and improve patients' quality of life by partially restoring myocardial reperfusion.

Myocardial Infarction 52

Myocardial Infarction Quality of Life Heart Transplant Ischemia 52

Cardiology Update

MARCH 5, 2024

In the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, researchers examined the risk of ischemic events in patients with stable coronary artery disease. years, with 57.1% occurring within 30 days after CABG. Original article: Redfors B et al.

Coronary Artery Disease 116

Coronary Artery Disease Ischemia Coronary Artery Bypass Graft Myocardial Infarction 116

Journal of the American Heart Association

APRIL 7, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundStrain assessed by cardiac magnetic resonance (CMR) is a key prognostic indicator in myocardial infarction. True MINOCA was defined by evidence of ischemia or infarction on CMR.

Myocardial Infarction 45

Myocardial Infarction Atrial Fibrillation Angina Ischemia 45

Journal of Cardiothoracic Surgery

APRIL 11, 2024

Background The clinical presentation of left ventricular free wall rupture (LVFWR) varies ranging from uneventful condition to congestive heart failure. Case summary Here we report two cases of LVFWR with different clinical presentation and notable outcome.

Ischemia 52

Ischemia Myocardial Infarction ICU Aortic 52

Journal of the American Heart Association

JANUARY 23, 2025

A cardiovascular reactivity risk score was calculated by allotting 0 to 3 points for each quartile of increasing abnormality for each of the 3 reactivity responses and summing the quartile points from the MIPS (Mental Stress Ischemia Prognosis Study) to yield a cardiovascular reactivity risk score ranging from 0 to 9.

Coronary Artery Disease 56

Coronary Artery Disease Outcomes Myocardial Infarction Risk Factors 56

Dr. Smith's ECG Blog

APRIL 8, 2016

If there is polymorphic VT with a long QT on the baseline ECG, then generally we call that Torsades, but Non-Torsades Polymorphic VT can result from ischemia alone. I have read articles that say that patients without ischemia are at low risk of complications from hypokalemia, But it is not entirely without risk. 1987;147(3):465-469.

STEMI 52

STEMI Myocardial Infarction Cardiac Arrest Arrhythmia 52

Journal of the American Heart Association

APRIL 3, 2025

This study aimed to elucidate the prognostic value of supranormal LVEF.MethodsThis retrospective cohort study analyzed patients referred for cardiac magnetic resonance imaging to assess myocardial ischemia or viability. Primary outcomes included cardiovascular death, heart failure, myocardial infarction, and stroke.

Outcomes 45

Outcomes Myocardial Infarction Ischemia Heart Failure 45

Frontiers in Cardiovascular Medicine

JUNE 26, 2024

ACS may arise from the disruption of an atherosclerotic plaque, ultimately leading to acute ischemia and myocardial infarction. The interplay between chronic LV remodeling and recurrent ischemic episodes delineates the progression of the disease toward heart failure and cardiovascular death.

Plaque 52

Plaque Myocardial Infarction Atherosclerosis Ischemia 52

Journal of the American Heart Association

MARCH 21, 2025

Study end points include mortality, cardiovascular events (hospitalization for acute myocardial infarction or stroke) and limb events (hospitalization for critical limb ischemia or major amputation) and were identified using Veterans Affairs and nonVeterans Affairs encounters.ResultsThe mean age was 70.6 were male, and 18.5%

Peripheral Arterial Disease 45

Peripheral Arterial Disease Outcomes Myocardial Infarction Kidney Disease 45

Dr. Smith's ECG Blog

NOVEMBER 12, 2020

Clin Chem [Internet] 2020;Available from: [link] Smith mini-review: Troponin in Emergency Department COVID patients Cardiac Troponin (cTn) is a nonspecific marker of myocardial injury. In normal times, the most common use of cTni is in diagnosing, or ruling out, acute myocardial infarction (AMI, a subcategory of acute myocardial injury.

Cardiac Arrest 52

Cardiac Arrest COVID-19 Myocardial Infarction Cardiogenic Shock 52

EMS 12-Lead

JUNE 1, 2022

Such findings would normally suggest primary ischemia with concomitant surveillance of coronary occlusion, but these ST/T changes might very well be secondary to the Escape mechanism at hand. The patient care narrative states no further changes in heart rate with persistent LBBB morphology. European Heart Journal, 28 , 2449-2455. [7]

Heart Failure 52

Heart Failure Myocardial Infarction Bradycardia Chest Pain 52

MIBHS

OCTOBER 15, 2024

These cells, known as cardiomyocytes, rely on a constant supply of oxygen to continue contracting and relaxing as part of the heart’s pumping action. Without oxygen, the cells would quickly die, leading to a heart attack (myocardial infarction). CAD is one of the leading causes of heart attacks.

Circulation 52

Circulation Heart Attack Heart attacks Chest Pain 52

Wellnest

DECEMBER 11, 2023

HIV and Cardiovascular Disease: HIV infection itself is associated with an increased risk of cardiovascular disease and can double the risk of CVDs, including myocardial infarction and stroke. Plus, abacavir, an NRTI, has been linked to an increased risk of myocardial infarction.

Quality of Life 52

Quality of Life Myocardial Infarction Public Health Arrhythmia 52

Dr. Smith's ECG Blog

OCTOBER 24, 2018

Therefore, this does not meet the definition of myocardial infarction ( 4th Universal Definition of MI ), which requires at least one troponin above the 99% reference range. This was clearly severe subepicardial ischemia causing ST Elevation, but it was not of a long enough duration to result in measurable infarct.

STEMI 40

STEMI Angina Myocardial Infarction Plaque 40

Cardiology Update

APRIL 30, 2024

The highly impactful International Study of Comparative Health Effectiveness With Medical and Invasive Approaches ( ISCHEMIA ) trial investigated the effectiveness of invasive (INV) versus conservative (CON) strategies for managing stable coronary artery disease. EuroIntervention. 2024 Mar 5:EIJ-D-24-00011.

Coronary Artery Disease 119

Coronary Artery Disease Ischemia Outcomes Cardiac Arrest 119

Journal of the American Heart Association

FEBRUARY 27, 2024

We evaluated the primary outcome (cardiovascular death, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest) and other end points, by sex, in 1168 (22.6%) women and 4011 (77.4%) men. of invasive‐assigned women revascularized versus 81.2%

Ischemia 45

Ischemia Coronary Artery Disease Myocardial Infarction Outcomes 45

Dr. Smith's ECG Blog

APRIL 8, 2015

Evidence of acute ischemia (may be subtle) vii. History of Cardiovascular disease (all studies): Especially any history of heart failure or structural cardiac disease, including valvular 4. to 1.64) for myocardial infarction or death from coronary heart disease, and 1.06 (95 percent confidence interval, 0.77

Arrhythmia 52

Arrhythmia Outcomes Chest Pain Risk Factors 52

Dr. Smith's ECG Blog

MARCH 19, 2025

They end up with high mortality and needless heart failure. Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded culprit artery - a systemic review and meta-analysis. This means that, in the United States alone, of 500,000 NSTEMI, 170,000 do not get the care they deserve.

Chest Pain 115

Chest Pain STEMI Stents Stent 115

Dr. Smith's ECG Blog

FEBRUARY 26, 2025

It could also, given a different clinical context be compatible with a subacute myocardial infarction complicated by post infarct regional pericarditis. Due to the atypical and vague symptoms, the myocardial infarct was not initially diagnosed. At presentation he had a history of dyspnea for 6 days.

Chest Pain 88

Chest Pain Pericarditis Myocardial Infarction Dementia 88

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2025

Acute myocardial infarction (MI) is a leading cause of death worldwide. Although with current treatment, acute mortality from MI is low, the damage and remodeling associated with MI are responsible for subsequent heart failure.

Myocardial Infarction 63

Myocardial Infarction Heart Failure Cancer Ischemia 63

Dr. Smith's ECG Blog

MARCH 8, 2025

It is possible there is microvascular dysfunction producing residual transmural ischemia. But this is most common when there is prolonged ischemia, and this patient had the fastest reperfusion imaginable! In addition to profound acute heart failure, the patient suffered from electrical storm. SanzRuiz, R., Solis, J., &

Cardiomyopathy 74

Cardiomyopathy Myocardial Infarction Defibrillator Bradycardia 74