Journal of Cardiothoracic Surgery

APRIL 4, 2024

Additionally, ischemia-reperfusion injury following cardioplegic arr. Cardiopulmonary bypass induces a systemic inflammatory response and alterations in fluid homeostasis, resulting in generalized tissue edema.

Open-Heart Surgery 52

Open-Heart Surgery Heart Failure Ischemia 52

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

Journal of the American Heart Association

FEBRUARY 3, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundThe early assessment of heart failure (HF) risk in patients with acute coronary syndrome (ACS) can help reduce mortality.

Heart Failure 40

Heart Failure Ischemia 40

Dr. Smith's ECG Blog

JANUARY 9, 2024

Are you confident there is no ischemia? The heart rate is about 130 bpm. The heart rate could be compatible with that of a 2:1 conducted atrial flutter. Primary VT , and the VT with tachycardia is causing ischemia with chest discomfort (supply-demand mismatch/type 2 MI)? Do you agree with this strategy?

Tachycardia 119

Tachycardia Electrophysiology Atrial Flutter Ischemia 119

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

This article evaluates the utility of S100A8/A9 protein as a biomarker and therapeutic target for diagnosing cardiovascular diseases, considering its structural features, fundamental biological properties, and its multifaceted influence on cardiovascular conditions including atherosclerosis, myocardial infarction, myocardial ischemia/reperfusion injury, (..)

Cardiovascular Disease 52

Cardiovascular Disease Myocardial Infarction Atherosclerosis Biomarkers 52

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Myocardial damage caused, for example, by cardiac ischemia leads to ventricular volume overload resulting in increased stretch of the remaining myocardium. Conversely, in response to extensive myocardial damage, cardiomyocytes in the adult zebrafish heart and neonatal mice proliferate and completely regenerate the damaged myocardium.

Ischemia 59

Ischemia Heart Failure 59

Dr. Smith's ECG Blog

AUGUST 6, 2024

In any case, the ECG is diagnostic of severe ischemia and probably OMI. So this could be myocarditis but in my opinion needs an angiogram before making that diagnosis. == Dr. Nossen Comment/Interpretation: Evaluation of ischemia on an ECG can be very challenging. Concordant STE of 1 mm in just one lead or 2a.

Chest Pain 104

Chest Pain Ischemia Pericarditis Tachycardia 104

Dr. Smith's ECG Blog

JUNE 27, 2021

The patient has heart failure as a result of this event. If this STD were due to LVH or to subendocardial ischemia, rather than posterior OMI, it would be maximal in V5 and V6. How could an occlusion (Occlusion MI, OMI) that results in the loss of a massive amount of myocardium and results in Heart Failure be missed?

Myocardial Infarction 40

Myocardial Infarction Ischemia STEMI Pulmonary 40

Journal of Cardiovascular Pharmacology

OCTOBER 24, 2024

In the heart, autophagy is regulated mainly through mitophagy due to the metabolic changes of cardiomyocytes caused by ischemia and hypoxia. Myocardial remodeling is characterized by gradual heart enlargement, cardiac dysfunction, and extraordinary molecular changes.

Myocardial Infarction 40

Myocardial Infarction Ischemia Heart Failure Heart Disease 40

Dr. Smith's ECG Blog

JANUARY 1, 2024

His medical history includes hypertension, a decade-long battle with diabetes, ischemic heart disease, a coronary bypass graft surgery ten years ago, a diagnosis of congestive heart failure for the last five years, and a prior ICD implantation five years ago. Thus VT is very probable.

Tachycardia 112

Tachycardia Blog Ischemia Heart Failure 112

Ken Grauer, MD

MAY 20, 2023

NOTE: It's important to correlate ongoing circumstances at the time that a prior tracing was done ( ie, Was the patient stable and asymptomatic — or were they having chest pain, an exacerbation of heart failure, or some other ongoing process at the time the prior ECG was recorded? ). Cardiol 27:674-677, 2004 ).

Blog 145

Blog Chest Pain Ischemia STEMI 145

DAIC

FEBRUARY 29, 2024

ET Murphy Ballroom 4 Comparison of an "Inclisiran First" Strategy with Usual Care in Patients With Atherosclerotic Cardiovascular Disease: Results From the VICTORION-INITIATE Randomized Trial Targeting Weight Loss to Personalize the Prevention of Type 2 Diabetes Once-weekly Semaglutide in Patients with Heart Failure With Preserved Ejection Fraction, (..)

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

Dr. Smith's ECG Blog

OCTOBER 18, 2023

Most such rhythms in the setting of ischemia are VF and will not convert without defibrillation. NT-pro-BNP peaked at 4831, consistent with heart failure. Instead, antiarrhythmic drugs such as amiodarone or ß-blockers may be needed — and/or treatment targeted to correcting ischemia. Acute ischemia?

Cardiac Arrest 122

Cardiac Arrest Tachycardia Cardiomyopathy Bradycardia 122

Dr. Smith's ECG Blog

MARCH 22, 2024

The fact that R waves 2 through 6 are junctional does make ischemia more difficult to interpret -- but not impossible. The Queen of Hearts does not care about rhythm analysis, she simply looks at the ECG and decides whether it represents OMI or not.

Chest Pain 114

Chest Pain STEMI Bradycardia Ischemia 114

Circulation

JANUARY 18, 2024

BACKGROUND:Cardiolipin is a mitochondrial-specific phospholipid that maintains integrity of the electron transport chain (ETC) and plays a central role in myocardial ischemia/reperfusion injury. Circulation, Ahead of Print. Tafazzin is an enzyme that is required for cardiolipin maturation.

Myocardial Infarction 45

Myocardial Infarction Heart Transplant Ischemia Transplant 45

Circulation

NOVEMBER 11, 2024

Analyses of cardiovascular magnetic resonance imaging (MRI) in the MESA cohort have shown that LV sphericity is an important mode of variation in cardiac structure that is associated with ischemia, heart failure, and atrial fibrillation.

Atrial Fibrillation 40

Atrial Fibrillation Ischemia Heart Failure Circulation 40

Dr. Smith's ECG Blog

JUNE 11, 2021

Accordingly, in the algorithm by Cai et al for patients with LBBB and ischemic symptoms ( See below ) — the first indication for PCI is clinical: patients with hemodynamic instability or acute heart failure. So there is now high pre-test probability + refractory ischemia + Modified Sgarbossa + dynamic ECG changes.

Chest Pain 52

Chest Pain Cardiac Arrest Ischemia Cardiogenic Shock 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionTransient Ischemic Attack (TIA) is a common neurologic condition characterized by temporary, focal cerebral ischemia that results in reversible neurological deficits without tissue infarction. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Diabetes 40

Diabetes Coronary Artery Disease Atrial Fibrillation Dementia 40

EMS 12-Lead

MAY 20, 2022

There is broad subendocardial ischemia as demonstrated by STE aVR with concomitant STD that almost appears appropriately maximal in Leads II and V5. There is LBBB-like morphology with persistent patterns of subendocardial ischemia. This is the initial ECG: The QRS is widened with a regular cadence, and there are no discernable P waves.

Cardiomyopathy 52

Cardiomyopathy Ischemia STEMI Coronary Angiogram 52

All About Cardiovascular System and Disorders

MARCH 26, 2024

They have heart failure sometimes. That is, there is renal ischemia due to clogging of capillaries, which leads to increased erythropoietin secretion and this causes decompensated erythrocytosis. So they do badly, but it develops only very late and in very few also. It produces cardiomegaly on X-ray in ASD Eisenmenger.

VSD 52

VSD Pulmonary Hemorrhage Hypertension 52

Dr. Smith's ECG Blog

MARCH 2, 2019

Diffuse ST depression with ST elevation in aVR: Is this pattern specific for global ischemia due to left main coronary artery disease? Ischemia b. ST depression: is it ischemia? Does this patient have hypertension and/or heart failure that has worsened? Reference: Knotts RJ , Wilson JM, Kim E, Huang HD, Birnbaum Y.

Sickle Cell Disease 52

Sickle Cell Disease Ischemia Dysrhythmia Chest Pain 52

Dr. Smith's ECG Blog

JANUARY 22, 2020

There was no evidence of ischemia. In addition to ruling out rate-slowing medication serum electrolyte disorders and/or ischemia/infarction as potential causes of bradyarrhythmias one should also rule out hypothyroidism + sleep apnea. We are not told how ischemia has been ruled out in this case. Hyperkalemia.

Pulmonary 52

Pulmonary AFIB Atrial Fibrillation Pacemaker 52

Cardiology Update

MARCH 5, 2024

In the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, researchers examined the risk of ischemic events in patients with stable coronary artery disease. years, with 57.1% occurring within 30 days after CABG. Original article: Redfors B et al.

Coronary Artery Disease 116

Coronary Artery Disease Ischemia Coronary Artery Bypass Graft Myocardial Infarction 116

Dr. Smith's ECG Blog

OCTOBER 6, 2023

All of this appears to be consistent with "No Reflow", or small vessel occlusion with persistent ischemia in spite of an open artery. --There is persistent ST elevation in leads V1-V4, with a lot of STE in V4 (another bad sign). The best predictor of good blush and high TMP is the ECG, specifically resolution of ST Elevation on the ECG.

Aneurysm 66

Aneurysm Chest Pain Cardiogenic Shock Blog 66

Dr. Smith's ECG Blog

FEBRUARY 15, 2018

100% occluded RCA with TIMI 0 flow Post drug-eluting stent placement with TIMI 3 flow While in the cath lab, she transiently developed complete heart block and became hypotensive requiring transvenous pacemaker placement and transient pressors. Peak troponin T was 3.00 ng/mL (highly elevated). Post-cath ECG with resolution of acute changes.

Chest Pain 52

Chest Pain Critical Care Article Pacemaker 52

Dr. Smith's ECG Blog

MARCH 15, 2023

These include: i ) Use of rate-slowing medication ( ie, ß-blockers, digoxin, verapamil/diltiazem, etc. ) ; ii ) Acute or recent infarction or ischemia; iii ) Hypothyroidism; iv ) Neurologic injury; v ) Electrolyte disturbance; and , vi ) Sleep apnea.

Atrial Fibrillation 52

Atrial Fibrillation AFIB Arrhythmia Exercise 52

Dr. Smith's ECG Blog

DECEMBER 27, 2018

It is important to appreciate that even before looking at the ECG itself — the chance of true chamber enlargement is greatly increased IF the patient is older, and has longstanding hypertension and/or underlying heart disease likely to predispose to chamber enlargement (ie, heart failure, cardiomyopathy, valvular disease, etc. ).

Chest Pain 40

Chest Pain Hypertension STEMI Heart Disease 40

Frontiers in Cardiovascular Medicine

MARCH 18, 2025

Finally, we also emphasize the preclinical/clinical translational significance of neutrophil-targeted strategies.

Cardiovascular Disease 52

Cardiovascular Disease Atrial Fibrillation Atherosclerosis Ischemia 52

Dr. Smith's ECG Blog

AUGUST 14, 2023

The flutter waves can conceal or mimic ischemic repolarization findings, but here I don't see any obvious findings of OMI or subendocardial ischemia. The rhythm is 2:1 atrial flutter. The QRS is around 100 msec wide (narrow), but with very abnormal morphology including a large R-wave in V1, deep S-wave in I, R-wave in aVR.

Chest Pain 52

Chest Pain Pulmonary Sickle Cell Disease Atrial Flutter 52

Frontiers in Cardiovascular Medicine

FEBRUARY 19, 2025

At present, the main methods to treat ischemic heart disease are drug therapy, intervention and operation. These methods only alleviate symptoms of heart failure and myocardial ischemia and improve patients' quality of life by partially restoring myocardial reperfusion.

Myocardial Infarction 52

Myocardial Infarction Quality of Life Heart Transplant Ischemia 52

MIBHS

OCTOBER 31, 2024

Dilation: The chambers of the heart expand, making the walls thinner. Both forms of enlargement may compromise the heart’s ability to pump blood efficiently, leading to further complications like heart failure. What Causes an Enlarged Heart? Here are some of the most common causes: 1.

Blood Pressure 52

Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

Dr. Smith's ECG Blog

MARCH 6, 2020

There is no evidence of infarction or ischemia. NT-proBNP values less than 300 pg/ml have a 99% negative predictive value for excluding congestive heart failure. A cutoff of 1200 pg/ml for patients with a normal eGFR is very specific for heart failure. Troponin I was 0.054 ng/mL NT-ProBNP was 8316 (0-900 pg/mL). "

Heart Failure 52

Heart Failure Tachycardia Atrial Flutter Cardiomyopathy 52

Journal of Cardiovascular Electrophysiology

NOVEMBER 15, 2024

Central illustration: In those presenting With monomorphic VT, undergoing coronary ischemia assessment was associated With improved 12-month event-free survival from the primary endpoint of VT recurrence, ICD therapy, heart failure hospitalization, and death.

Ischemia 40

Ischemia Tachycardia Outcomes Heart Failure 40

Dr. Smith's ECG Blog

OCTOBER 20, 2024

The first task when assessing a wide complex QRS for ischemia is to identify the end of the QRS. The ST segment changes are compatible with severe subendocardial ischemia which can be caused by type I MI from ACS or potentially from type II MI (non-obstructive coronary artery disease with supply/demand mismatch). What do you think?

Cardiogenic Shock 128

Cardiogenic Shock Ischemia Chest Pain Cardiac Arrest 128

Journal of Cardiothoracic Surgery

APRIL 11, 2024

Background The clinical presentation of left ventricular free wall rupture (LVFWR) varies ranging from uneventful condition to congestive heart failure. Case summary Here we report two cases of LVFWR with different clinical presentation and notable outcome.

Ischemia 52

Ischemia Myocardial Infarction ICU Aortic 52

DAIC

FEBRUARY 14, 2025

Critical limb-threatening ischemia (CLTI) represents the end stage of peripheral artery disease (PAD), when poor circulation due to blockages in the arteries causes symptoms including numbness, sores that will not heal, gangrene, and extreme pain. When we save a limb, we save a life.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Cancer Innovation Best Practices 52

Frontiers in Cardiovascular Medicine

FEBRUARY 6, 2024

Risk stratification of cardiovascular death and treatment strategies in patients with heart failure (HF), the optimal timing for valve replacement, and the selection of patients for implantable cardioverter defibrillators are based on an echocardiographic calculation of left ventricular ejection fraction (LVEF) in most guidelines.

Defibrillator 64

Defibrillator Ischemia Heart Failure 64