Frontiers in Cardiovascular Medicine

JANUARY 22, 2024

Myocardial ischemia may induce myocardial fibrosis, a condition that progressively leads to ventricular remodeling, heightening the risk of heart failure. 68 Ga-FAPI-04 PET/CT shows promise in assessing fibroblast activation in patients with early myocardial infarction characterized by prolonged myocardial ischemia.

Angina 69

Angina Ischemia Myocardial Infarction Electrocardiogram 69

The American Journal of Cardiology

JANUARY 1, 2025

Publication date: Available online 31 December 2024 Source: The American Journal of Cardiology Author(s): Takuma Takada, Eiji Shibahashi, Shun Hasegawa, Ayano Yoshida, Makoto Kishihara, Shonosuke Watanabe, Shota Shirotani, Takuro Abe, Masashi Nakao, Junichi Yamaguchi, Kentaro Jujo

Ischemia 40

Ischemia Heart Failure 40

Dr. Smith's ECG Blog

JANUARY 2, 2025

It should be kept in mind that on occasions, beta-one agonist can result in increased ventricular ectopy e.g., in severe myocardial ischemia (by increasing myocardial demand), or sometimes with congenital long-QT syndrome. Smith, this can be accomplished by either using beta-one agonists or temporary transvenous pacing.

Tachycardia 116

Tachycardia Cardiomyopathy Blog Bradycardia 116

MIBHS

OCTOBER 31, 2024

Dilation: The chambers of the heart expand, making the walls thinner. Both forms of enlargement may compromise the heart’s ability to pump blood efficiently, leading to further complications like heart failure. What Causes an Enlarged Heart? Here are some of the most common causes: 1.

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Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

The American Journal of Cardiology

FEBRUARY 6, 2025

Publication date: Available online 5 February 2025 Source: The American Journal of Cardiology Author(s): Sravani Modumudi, Chandana Padmanabham Reddy

Ischemia 40

Ischemia Heart Failure 40

Journal of Cardiothoracic Surgery

APRIL 11, 2024

Background The clinical presentation of left ventricular free wall rupture (LVFWR) varies ranging from uneventful condition to congestive heart failure. Case summary Here we report two cases of LVFWR with different clinical presentation and notable outcome.

Ischemia 52

Ischemia Myocardial Infarction ICU Aortic 52

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

Journal of the American Heart Association

FEBRUARY 3, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundThe early assessment of heart failure (HF) risk in patients with acute coronary syndrome (ACS) can help reduce mortality.

Heart Failure 40

Heart Failure Ischemia 40

Dr. Smith's ECG Blog

JANUARY 9, 2024

Are you confident there is no ischemia? The heart rate is about 130 bpm. The heart rate could be compatible with that of a 2:1 conducted atrial flutter. Primary VT , and the VT with tachycardia is causing ischemia with chest discomfort (supply-demand mismatch/type 2 MI)? Do you agree with this strategy?

Tachycardia 119

Tachycardia Electrophysiology Atrial Flutter Ischemia 119

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

This article evaluates the utility of S100A8/A9 protein as a biomarker and therapeutic target for diagnosing cardiovascular diseases, considering its structural features, fundamental biological properties, and its multifaceted influence on cardiovascular conditions including atherosclerosis, myocardial infarction, myocardial ischemia/reperfusion injury, (..)

Cardiovascular Disease 52

Cardiovascular Disease Myocardial Infarction Atherosclerosis Article 52

Dr. Smith's ECG Blog

OCTOBER 20, 2024

The first task when assessing a wide complex QRS for ischemia is to identify the end of the QRS. The ST segment changes are compatible with severe subendocardial ischemia which can be caused by type I MI from ACS or potentially from type II MI (non-obstructive coronary artery disease with supply/demand mismatch). What do you think?

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Cardiogenic Shock Ischemia Chest Pain Cardiac Arrest 128

DAIC

FEBRUARY 14, 2025

Critical limb-threatening ischemia (CLTI) represents the end stage of peripheral artery disease (PAD), when poor circulation due to blockages in the arteries causes symptoms including numbness, sores that will not heal, gangrene, and extreme pain. When we save a limb, we save a life.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Cancer Innovation Best Practices 52

Dr. Smith's ECG Blog

JANUARY 20, 2024

Last ECG: Final Diagnosis: "NSTEMI" This patient will likely suffer heart failure and early death due to the diagnosis of "NSTEMI" Learning Points: Despite NSTEMI guidelines recommending emergent angiography for NSTEMI patients with refractory ischemic symptoms, this is simply not done in many systems, and this has been recorded in a study as well.

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Chest Pain STEMI Hypertension Blog 121

Frontiers in Cardiovascular Medicine

FEBRUARY 6, 2024

Risk stratification of cardiovascular death and treatment strategies in patients with heart failure (HF), the optimal timing for valve replacement, and the selection of patients for implantable cardioverter defibrillators are based on an echocardiographic calculation of left ventricular ejection fraction (LVEF) in most guidelines.

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Defibrillator Ischemia Heart Failure 64

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Myocardial damage caused, for example, by cardiac ischemia leads to ventricular volume overload resulting in increased stretch of the remaining myocardium. Conversely, in response to extensive myocardial damage, cardiomyocytes in the adult zebrafish heart and neonatal mice proliferate and completely regenerate the damaged myocardium.

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Ischemia Heart Failure 59

Dr. Smith's ECG Blog

AUGUST 6, 2024

In any case, the ECG is diagnostic of severe ischemia and probably OMI. So this could be myocarditis but in my opinion needs an angiogram before making that diagnosis. == Dr. Nossen Comment/Interpretation: Evaluation of ischemia on an ECG can be very challenging. Concordant STE of 1 mm in just one lead or 2a.

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Chest Pain Ischemia Pericarditis Tachycardia 104

Frontiers in Cardiovascular Medicine

JUNE 26, 2024

ACS may arise from the disruption of an atherosclerotic plaque, ultimately leading to acute ischemia and myocardial infarction. The interplay between chronic LV remodeling and recurrent ischemic episodes delineates the progression of the disease toward heart failure and cardiovascular death.

Plaque 52

Plaque Myocardial Infarction Atherosclerosis Ischemia 52

Dr. Smith's ECG Blog

JUNE 27, 2021

The patient has heart failure as a result of this event. If this STD were due to LVH or to subendocardial ischemia, rather than posterior OMI, it would be maximal in V5 and V6. How could an occlusion (Occlusion MI, OMI) that results in the loss of a massive amount of myocardium and results in Heart Failure be missed?

Myocardial Infarction 40

Myocardial Infarction Ischemia STEMI Pulmonary 40

Journal of the American Heart Association

JANUARY 23, 2025

A cardiovascular reactivity risk score was calculated by allotting 0 to 3 points for each quartile of increasing abnormality for each of the 3 reactivity responses and summing the quartile points from the MIPS (Mental Stress Ischemia Prognosis Study) to yield a cardiovascular reactivity risk score ranging from 0 to 9.

Coronary Artery Disease 56

Coronary Artery Disease Outcomes Myocardial Infarction Risk Factors 56

Journal of Cardiovascular Pharmacology

OCTOBER 24, 2024

In the heart, autophagy is regulated mainly through mitophagy due to the metabolic changes of cardiomyocytes caused by ischemia and hypoxia. Myocardial remodeling is characterized by gradual heart enlargement, cardiac dysfunction, and extraordinary molecular changes.

Myocardial Infarction 40

Myocardial Infarction Ischemia Heart Failure Heart Disease 40

Dr. Smith's ECG Blog

JANUARY 1, 2024

His medical history includes hypertension, a decade-long battle with diabetes, ischemic heart disease, a coronary bypass graft surgery ten years ago, a diagnosis of congestive heart failure for the last five years, and a prior ICD implantation five years ago. Thus VT is very probable.

Tachycardia 112

Tachycardia Blog Ischemia Heart Failure 112

Journal of the American Heart Association

MARCH 21, 2025

Study end points include mortality, cardiovascular events (hospitalization for acute myocardial infarction or stroke) and limb events (hospitalization for critical limb ischemia or major amputation) and were identified using Veterans Affairs and nonVeterans Affairs encounters.ResultsThe mean age was 70.6 were male, and 18.5% At 1 year, 9.4%

Peripheral Arterial Disease 45

Peripheral Arterial Disease Outcomes Myocardial Infarction Kidney Disease 45

Ken Grauer, MD

MAY 20, 2023

NOTE: It's important to correlate ongoing circumstances at the time that a prior tracing was done ( ie, Was the patient stable and asymptomatic — or were they having chest pain, an exacerbation of heart failure, or some other ongoing process at the time the prior ECG was recorded? ). Cardiol 27:674-677, 2004 ).

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Blog Chest Pain Ischemia STEMI 144

Frontiers in Cardiovascular Medicine

JANUARY 14, 2024

The rate of composite outcome (in-hospital death, stroke/global ischemia, dialysis, and/or acute heart failure) was 41.2%, and 10-year mortality rate was 47.0%. In the validation dataset (2,229 patients), the rate of in-hospital mortality was 18.4%.

Risk Factors 64

Risk Factors Hospital Aortic Ischemia 64

Dr. Smith's ECG Blog

OCTOBER 18, 2023

Most such rhythms in the setting of ischemia are VF and will not convert without defibrillation. NT-pro-BNP peaked at 4831, consistent with heart failure. Instead, antiarrhythmic drugs such as amiodarone or ß-blockers may be needed — and/or treatment targeted to correcting ischemia. Acute ischemia?

Cardiac Arrest 122

Cardiac Arrest Tachycardia Cardiomyopathy Bradycardia 122

DAIC

FEBRUARY 29, 2024

ET Murphy Ballroom 4 Comparison of an "Inclisiran First" Strategy with Usual Care in Patients With Atherosclerotic Cardiovascular Disease: Results From the VICTORION-INITIATE Randomized Trial Targeting Weight Loss to Personalize the Prevention of Type 2 Diabetes Once-weekly Semaglutide in Patients with Heart Failure With Preserved Ejection Fraction, (..)

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Aortic valve Myocardial Infarction Aortic Blood Pressure 103

DAIC

JUNE 13, 2024

Use of this device may cause serious injury, including blood loss, tearing in the artery (perforation), unstable blood pressure (hemodynamic instability), prevention of blood flow to the heart (myocardial ischemia), or death. Teleflex/Arrow International reports 322 complaints.

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Aortic Blood Pressure Ischemia Heart Failure 115

Dr. Smith's ECG Blog

MARCH 22, 2024

The fact that R waves 2 through 6 are junctional does make ischemia more difficult to interpret -- but not impossible. The Queen of Hearts does not care about rhythm analysis, she simply looks at the ECG and decides whether it represents OMI or not.

Chest Pain 114

Chest Pain STEMI Bradycardia Ischemia 114

Circulation

JANUARY 18, 2024

BACKGROUND:Cardiolipin is a mitochondrial-specific phospholipid that maintains integrity of the electron transport chain (ETC) and plays a central role in myocardial ischemia/reperfusion injury. Circulation, Ahead of Print. Tafazzin is an enzyme that is required for cardiolipin maturation.

Myocardial Infarction 45

Myocardial Infarction Heart Transplant Ischemia Transplant 45

Dr. S. Venkatesan MD

FEBRUARY 20, 2024

SCD is the leading cause of mortality in heart failure. The simple reason could be we can address the ischemia a potential arrhythmic target by some form of revascularization in IDCM. Bardy GH, Lee KL, Mark DB, Poole JE, Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. N Engl J Med.

Defibrillator 52

Defibrillator Heart Failure Sudden Cardiac Death Cardiomyopathy 52

Heart 2023 Conference

APRIL 20, 2022

Source: JAMA Cardiology) Patients with afib who survived an intracerebral haemorrhage had a very significant risk of cerebrovascular ischemia episodes and death in the following year, according to registry data. American College of Cardiology Journal) Are you thinking of stopping your antiplatelet medication too soon after angioplasty?

Pulmonary 52

Pulmonary Hypertension AFIB COVID-19 52

Circulation

NOVEMBER 11, 2024

Analyses of cardiovascular magnetic resonance imaging (MRI) in the MESA cohort have shown that LV sphericity is an important mode of variation in cardiac structure that is associated with ischemia, heart failure, and atrial fibrillation.

Atrial Fibrillation 40

Atrial Fibrillation Ischemia Heart Failure Circulation 40

Dr. Smith's ECG Blog

JUNE 11, 2021

Accordingly, in the algorithm by Cai et al for patients with LBBB and ischemic symptoms ( See below ) — the first indication for PCI is clinical: patients with hemodynamic instability or acute heart failure. So there is now high pre-test probability + refractory ischemia + Modified Sgarbossa + dynamic ECG changes.

Chest Pain 52

Chest Pain Cardiac Arrest Ischemia Cardiogenic Shock 52

EMS 12-Lead

JUNE 1, 2022

Such findings would normally suggest primary ischemia with concomitant surveillance of coronary occlusion, but these ST/T changes might very well be secondary to the Escape mechanism at hand. LBBB may be the precipitating cause of the heart failure syndrome, or may portend high mortality when identified in preexisting heart failure.

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Heart Failure Myocardial Infarction Bradycardia Chest Pain 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionTransient Ischemic Attack (TIA) is a common neurologic condition characterized by temporary, focal cerebral ischemia that results in reversible neurological deficits without tissue infarction. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

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Diabetes Coronary Artery Disease Atrial Fibrillation Dementia 40

EMS 12-Lead

MAY 20, 2022

There is broad subendocardial ischemia as demonstrated by STE aVR with concomitant STD that almost appears appropriately maximal in Leads II and V5. There is LBBB-like morphology with persistent patterns of subendocardial ischemia. This is the initial ECG: The QRS is widened with a regular cadence, and there are no discernable P waves.

Cardiomyopathy 52

Cardiomyopathy Ischemia STEMI Coronary Angiogram 52

DAIC

FEBRUARY 14, 2025

Critical limb-threatening ischemia (CLTI) represents the end stage of peripheral artery disease (PAD), when poor circulation due to blockages in the arteries causes symptoms including numbness, sores that will not heal, gangrene, and extreme pain. When we save a limb, we save a life.

Hospital 52

Hospital Peripheral Arterial Disease Cancer Innovation 52