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Heart Failure Hypertension Obesity 
American College of Cardiology
AUGUST 7, 2024
In this week’s View, Dr. Eagle looks at post-capillary pulmonary hypertension in heart failure and the revised European guideline definition. He then explores obesity in adolescents and its impact on our societal health.
53 
Open Heart
MAY 23, 2024
Pre-eclampsia and heart failure have common risk factors, including hypertension, obesity and diabetes. It is not known whether heart failure increases the risk of pre-eclampsia. This study examines whether pregestational heart failure increases the risk of pre-eclampsia.
American College of Cardiology
JANUARY 8, 2024
Obesity is a multifaceted disease that is directly and indirectly implicated in atherosclerotic cardiovascular disease (CVD), heart failure (HF), atrial fibrillation (AF), and multiple CVD risk factors, including dyslipidemia, hypertension, type 2 diabetes mellitus (DM), and sleep disorders.
68 
MIBHS
FEBRUARY 15, 2025
High blood pressure, also known as hypertension, is a common condition that affects millions of people worldwide. Often referred to as the silent killer, hypertension can quietly damage your heart and other vital organs over time. Hypertension is diagnosed when blood pressure consistently reads 130/80 mm Hg or higher.
Frontiers in Cardiovascular Medicine
JULY 17, 2024
Recently, indisputable evidence has shown that the TyG index is strongly associated with cardiovascular disease [CVD, including atherosclerosis, heart failure (HF), and hypertension] prognosis and mortality. Finally, we summarized the mechanism of the “obesity paradox.”
CardiacWire
AUGUST 23, 2024
It looks like we might be able to add prediabetes and hypertension to the growing list of conditions that Eli Lilly’s “weight loss drug” tirzepatide is able to treat, after new analysis of the SURMOUNT-1 trial showed significant reductions in blood pressure and diabetes progression. mm Hg systolic and 4.2 of placebo-takers.
64 
Journal of Clinical Investigation - Cardiology
DECEMBER 15, 2023
Heart failure with preserved ejection fraction (HFpEF) is a widespread syndrome with limited therapeutic options and poorly understood immune pathophysiology.
Frontiers in Cardiovascular Medicine
DECEMBER 17, 2023
These conditions have an increasing share in the health burden worldwide due to worsening endemic of hypertension, obesity, and diabetes. However, the same set of genes were significantly induced in the Trp53inp2-cKO hearts under both mechanical and metabolic stresses.
European Journal of Heart Failure
DECEMBER 7, 2023
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. Overall, 60.9%
American College of Cardiology
NOVEMBER 5, 2024
The idea that obesity increases the risk of heart failure seems like an obvious conclusion. After all, as the Framingham Heart Study clearly showed, obesity and overweight are significantly associated with a higher risk of hypertension, angina and coronary heart disease.
Journal of the American Heart Association
DECEMBER 29, 2023
AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.
45 Circulation: Heart Failure
JANUARY 28, 2025
Circulation: Heart Failure, Ahead of Print. BACKGROUND:The therapeutic armamentarium for heart failure with preserved ejection fraction (HFpEF) remains notably constrained. compared with single condition exposure 5.21.3% (obesity), 6.73.5% (hypertension), and 9.01.1% (diabetes;P<0.001).
Circulation
JUNE 4, 2024
We projected through 2050, overall and by age and race and ethnicity, accounting for changes in disease prevalence and demographics.RESULTS:We estimate that among adults, prevalence of hypertension will increase from 51.2% to 26.8%) and obesity (43.1% to 9.2%), heart failure (2.7% in 2020 to 61.0% Diabetes (16.3%
81 
DAIC
JUNE 18, 2024
A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 trillion by 2050, according to two American Heart Association ( AHA ) presidential advisories published June 4 in the AHA journal Circulation. "The
105 
HeartRhythm
SEPTEMBER 4, 2024
Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) are comorbid conditions that are increasingly prevalent and have a high socioeconomic burden. This article discusses their shared pathophysiology, focusing on the triad of hypertension, obesity, and aging.We
Circulation: Heart Failure
MARCH 8, 2024
Circulation: Heart Failure, Ahead of Print. Background:Current prevalence estimates of heart failure (HF) are primarily based on self-report or HF hospitalizations. Results:Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White.
Circulation
NOVEMBER 11, 2024
Intro:Drug Development for Heart failure with Preserved Ejection Fraction (HFpEF) is a major challenge facing cardiovascular research due to its complex pathophysiology and existence of comorbidities, leading to recognize distinct HFpEF phenogroups. Circulation, Volume 150, Issue Suppl_1 , Page A4139791-A4139791, November 12, 2024.
Journal of the American Heart Association
FEBRUARY 26, 2025
Multimorbidity was defined as 2 comorbidities (heart failure, hypertension, diabetes, coronary heart disease, kidney dysfunction, moderate or severe mitral valve regurgitation, or obesity). AF symptom severity was assessed via the University of Toronto AF Severity Scale questionnaire.
HeartRhythm
MARCH 12, 2024
2 As noted elsewhere,3 DM and AF affect a population that shares concomitant conditions such as obesity, hypertension and even heart failure (HF). In the United States the Center for Disease Control and Prevention estimates that it affects 11.6% of the population.1 Further, DM is a major risk for AF.
Wellnest
FEBRUARY 28, 2023
Sleep Issues Are Caused by Heart Failure Heart failure complications may impact your sleep. Obstructive sleep apnea (OSA), a respiratory disorder, has been connected to heart disease, obesity, diabetes, stroke, and high blood pressure. They also have an increased risk of having a stroke or a heart attack.
Journal of the American Heart Association
MARCH 18, 2024
Changes in BCAA homeostasis have emerged as pivotal contributors in the pathophysiology of several cardiometabolic diseases, including type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, and heart failure.
40 
ADN Center of Excellence
SEPTEMBER 2, 2024
AFib is associated with a fivefold increased risk of stroke, and it is also linked to heart failure, chronic fatigue, and other serious health issues. Factors such as aging populations, rising rates of obesity, hypertension, and other cardiovascular conditions contribute to this increase.
59 Journal of the American Heart Association
MARCH 27, 2025
Six multimorbidity patterns were identified, including 4 specific patterns: (1) pattern 1, cerebrovascular cluster (histories of cerebrovascular disease and hypertension); (2) pattern 2, traditional cardiovascular disease risk factors cluster (histories of hyperlipidemia, obesity, anddiabetes, and family history of cardiovascular disease and smoking); (..)
Circulation
NOVEMBER 11, 2024
The CardioMEMS PA (pulmonary artery) sensor allows remote pulmonary artery diastolic (PAD) pressure monitoring to adjust diuresis in heart failure with preserved ejection fraction (HFpEF). In our case, the use of CardioMEMS PA sensor system allowed a novel perspective of assessing hemodynamic impact of cardiac myosin inhibitors.
Circulation
APRIL 1, 2025
BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but effective treatments are lacking. Cardiac lymphatics play a crucial role in maintaining heart health by draining fluids and immune cells.
ADN Center of Excellence
SEPTEMBER 2, 2024
AFib is associated with a fivefold increased risk of stroke, and it is also linked to heart failure, chronic fatigue, and other serious health issues. Factors such as aging populations, rising rates of obesity, hypertension, and other cardiovascular conditions contribute to this increase.
52 
MIBHS
JULY 31, 2024
Here are some of the major ways in which chronic stress negatively impacts cardiovascular health: High Blood Pressure When you experience stress, your body releases hormones like cortisol and adrenaline, which cause your heart rate and blood pressure to spike.
DAIC
FEBRUARY 29, 2024
ET Main Tent (Hall B1) Effect of Gamification, Financial Incentives or Both Combined to Increase Physical Activity Among Patients with Elevated Risk For Major Adverse Cardiovascular Events.
103 
Journal of the American Heart Association
MARCH 19, 2025
The end point was the development of cardiotoxicity (defined as clinical heart failure or drop in left ventricular ejection fraction 10% to 50%).ResultsA Hypertension, diabetes, hyperlipidemia, obesity, and low socioeconomic status were more common in NH Black and Hispanic individuals. NonHispanic [NH] White, 30.5%
40 
DAIC
DECEMBER 19, 2023
The device is a patented 3-lead, 2-channel wireless continuous ECG wearable device that allows physicians the ability to address and assess sleep and heart health remotely. Undiagnosed and untreated sleep apnea increases the risk of costly health complications like heart disease, hypertension, diabetes, and depression.
Stroke Journal
FEBRUARY 1, 2024
Regarding comorbidities, congestive heart failure (OR 1.73, p <0.01, CI 1.32 Regarding comorbidities, congestive heart failure (OR 1.73, p <0.01, CI 1.32 to 2.26) and liver disease (OR 2.20, p < 0.01, CI 1.27 to 2.26) and liver disease (OR 2.20, p < 0.01, CI 1.27
40 Stroke Journal
JANUARY 30, 2025
In unadjusted analysis, factors significantly associated with troponin testing were a triage complaint of chest pain, older age, higher mean systolic BP, hypertension, diabetes, obesity, stroke or TIA, congestive heart failure, or coronary disease.
40 Stroke Journal
FEBRUARY 1, 2024
VRFs included hypertension, dyslipidemia, obesity, smoking, atrial fibrillation, coronary artery disease, heart failure, diabetes, and sleep apnea. Patients aged 18-55 with a diagnosis of IS were included and separated into two age groups: 18-35 and 36-55.
40 
AMS Cardiology
AUGUST 15, 2023
Family history – If a close family member has had heart disease, it can raise your risk. High blood pressure – Hypertension is a significant risk factor for heart disease. Routine blood pressure checks are essential to maintaining a healthy heart as high blood pressure often has no symptoms.
Stroke: Vascular and Interventional Neurology
NOVEMBER 9, 2023
They had a higher prevalence of diabetes (23.38% vs 18.82%), hypertension (74.34% vs 70.12%), obesity (13.95% vs 12.25%), dyslipidemia (38.17% vs 33.02%), smoking (39.30% vs 37.43%), prior TIA/ischemic stroke (22.60% vs 20.39%), coronary artery disease (15.03%), DVT (6.06% vs 3.51%), peripheral vascular disease (14.24% vs 11.09%), chronic renal failure (..)
40 
DAIC
MARCH 26, 2025
Food and Drug Administration (FDA) accepted its supplemental new drug application (sNDA) and granted Priority Review designation for KERENDIA(finerenone) for the treatment of adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF).
European Journal of Heart Failure
APRIL 13, 2025
The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. BMI, body mass index; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide.
European Journal of Heart Failure
APRIL 6, 2025
Abstract Aims Oxidative stress is known to be involved in the pathophysiology of heart failure (HF). To assess oxidative stress, direct quantification of reactive oxygen species would be ideal but this is not feasible due to their short half-lives.
Cardiometabolic Health Congress
JULY 25, 2023
Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.
52 
Dr. Paddy Barrett
AUGUST 9, 2024
The 14 Factors Include: Hearing Loss High LDL cholesterol Less Education Traumatic Brain Injury Depression Social Isolation Hypertension Obesity Smoking Excess Alcohol Diabetes Physical Inactivity Air Pollution Visual Loss Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission When You Intervene Matters.
115 
Journal of the American Heart Association
JANUARY 23, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundCardiometabolic comorbidities such as obesity, diabetes, and hypertension are highly prevalent in heart failure (HF).
DAIC
SEPTEMBER 11, 2024
A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. Earlier projections had estimated that 3.3 million U.S. The study appears Sept. The study appears Sept.
DAIC
JUNE 26, 2024
Getty Images milla1cf Wed, 06/26/2024 - 18:59 June 26, 2024 — Semaglutide , a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options. The study analyzed the effects of semaglutide 2.4
DAIC
MARCH 29, 2024
About Heart Failure Heart failure (HF) is a chronic, progressive disease in which the heart cannot pump enough blood to meet the body's needs. HFpEF is HF with preserved ejection fraction in which pressure builds up in the heart and lungs due to a stiffened left ventricle. CEO of V-Wave.
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