DAIC

MARCH 26, 2025

Food and Drug Administration (FDA) accepted its supplemental new drug application (sNDA) and granted Priority Review designation for KERENDIA(finerenone) for the treatment of adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF).

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Heart Failure Preserved Ejection Fraction Kidney Disease ACE Inhibitor 52

ECG Cases

AUGUST 19, 2024

We over-admit low risk acute heart failure patients and under-admit high risk heart failure patients. The post Ep 197 Acute Heart Failure Risk Stratification and Disposition appeared first on Emergency Medicine Cases.

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Heart Failure 125

American Heart News - Heart News

OCTOBER 10, 2024

Statement Highlights: Previous studies have found that 14-81% of patients with heart failure experience some degree of cognitive impairment affecting language, memory or executive function. Evidence also indicates that people with atrial fibrillation.

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Atrial Fibrillation Heart Failure Heart Disease 142

Science Daily - Heart Disease

AUGUST 1, 2024

A new small study has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).

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Heart Failure Preserved Ejection Fraction Obesity 118

Medical Xpress - Cardiology

JULY 29, 2024

An analysis of blood samples from thousands of study participants, led by researchers at UT Southwestern Medical Center, revealed 18 proteins associated with both heart failure and frailty, conditions that commonly develop in late life.

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Heart Failure Research 138

DAIC

MARCH 6, 2024

a biomarker-guided predictive care company, has presented data showing its FDA-cleared, non-invasive, biomarker-based technology for remote heart failure monitoring detected twice as many heart failure events as compared to the weight-based standard of care. Bodyport Inc., Image courtesy: Bodyport Inc.

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Heart Failure Technology Biomarkers Hospital 128

Medical Xpress - Cardiology

JANUARY 31, 2025

People hospitalized for infectionsalmost any infectionsare at substantially increased risk years later for heart failure, according to collaborative research by the University of Minnesota and Mayo Clinic.

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Heart Failure Hospital Research 124

Becker's Hospital Review - Cardiology

SEPTEMBER 3, 2024

have the lowest death rate for heart failure patients in the country, according to CMS data. Chicago-based Northwestern Memorial Hospital and VA Boston Healthcare System-Jamaica Plain (Mass.)

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Heart Failure Hospital CMS 124

Science Daily - Heart Disease

JANUARY 2, 2025

In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.

Heart Failure 120

Heart Failure Research 120

Frontiers in Cardiovascular Medicine

JANUARY 22, 2025

BackgroundHeart failure (HF) is a clinical syndrome resulting from structural damage or dysfunction of the heart. Previous investigations have highlighted the critical involvement of immune cells in the progression of heart failure, with distinct roles attributed to different types of immune cells.

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Heart Failure Research 52

Frontiers in Cardiovascular Medicine

MARCH 5, 2025

The association between ACC and clinical outcomes in HF patients was analyzed using Cox proportional hazards regression and restricted cubic spline models.ResultsA total of 4,737 heart failure patients were included.

Heart Failure 52

Heart Failure Hospital Outcomes Research 52

Cardiology Update

AUGUST 4, 2024

Despite proven benefits in reducing morbidity and mortality, many heart failure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). ESC Heart Failure 2024; 11 : 560–569. The post Digital Consults to Enhance Heart Failure Treatment: The ADMINISTER Trial appeared first on Cardiology Update.

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Heart Failure ACE Inhibitor COVID-19 Quality of Life 119

Becker's Hospital Review - Cardiology

JANUARY 27, 2025

In partnership with Abbott, the American Heart Association has launched a $3 million initiative to address knowledge gaps found within heart failure treatment education that may be contributing to cardiovascular care disparities.

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Education Heart Failure Hospital 115

DAIC

MARCH 25, 2025

Ten presentations will feature new data from the pivotal Phase III FINEARTS-HF cardiovascular (CV) outcomes trial, which investigated KERENDIA for treatingt adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF). Additional ACC.25

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Preserved Ejection Fraction Heart Failure Kidney Disease Research 52

JAMA Cardiology

SEPTEMBER 26, 2024

This prespecified analysis of the Finerenone Trial to Investigate the Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial investigates the long-term effects of treatment with the nonsteroidal mineralocorticoid receptor antagonist, finerenone, in patients with heart failure with mildly reduced (..)

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Heart Failure Preserved Ejection Fraction 111

Science Daily - Heart Disease

SEPTEMBER 2, 2024

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial.

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Preserved Ejection Fraction Heart Failure Hospital 123

Frontiers in Cardiovascular Medicine

NOVEMBER 21, 2024

However, its role in critically ill patients with acute heart failure (acute HF) remains underexplored.MethodsWe conducted a retrospective cohort study on patients with acute HF included in the Medical Information Mart for Intensive Care IV (MIMIC-IV) version 2.2 database.

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Heart Failure Research 59

Science Daily - Heart Disease

OCTOBER 23, 2024

Researchers have reduced scar formation and improved heart function in mouse models of heart failure using a monoclonal antibody treatment, similar to that approved by the FDA to treat other conditions.

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Heart Failure Heart Attack Heart attacks Research 115

JAMA Cardiology

MARCH 4, 2025

This Viewpoint recommends simultaneous or rapid sequence initiation of combination therapy with 3 specific classes of medication for heart failure with mildly reduced ejection fraction or preserved ejection fraction.

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Preserved Ejection Fraction Heart Failure 111

American Heart News - Heart News

JULY 24, 2024

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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Preserved Ejection Fraction Heart Failure Research 119

Becker's Hospital Review - Cardiology

AUGUST 14, 2024

Luke's Regional Medical Center has the lowest readmission rate for heart failure patients, CMS found. Boise, Idaho-based St.

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Heart Failure CMS Hospital 116

Science Daily - Heart Disease

MARCH 7, 2025

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

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Heart Failure Research 108

Science Daily - Heart Disease

AUGUST 19, 2024

Heart failure is a leading cause of death worldwide and is especially deadly for people who don't have access to medical facilities.

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Heart Failure Biomarkers Research 104

HCPLive

FEBRUARY 12, 2025

Meta-analysis suggests iron therapy lowers the risk of heart failure hospitalization and cardiovascular death in patients with chronic kidney disease.

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Heart Failure Kidney Disease Hospital 120

European Journal of Heart Failure

MARCH 10, 2025

Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis. Clonal haematopoiesis and heart failure: a meta-analysis. CH, clonal haematopoiesis; CI, confidence interval; HF, heart failure.

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Heart Failure Outcomes Coronary Artery Disease Risk Factors 40

JAMA Cardiology

FEBRUARY 25, 2025

This secondary analysis of the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial evaluates the effect of finerenone on outpatient worsening heart failure events requiring oral diuretic intensification among patients with heart failure with mildly reduced or (..)

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Preserved Ejection Fraction Outpatient Heart Failure 111

Heart BMJ

FEBRUARY 12, 2025

In adults with congenital heart disease (ACHD patients), atrial arrhythmias (AA) and heart failure (HF) are common. 1 Factors related to congenital heart disease, such as underlying anatomy, surgical repair technique and scars, can all be considered as AA substrates.

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Congenital Heart Disease Congenital Heart Failure Arrhythmia 59

Science Daily - Heart Disease

JULY 29, 2024

A novel study co-authored by a heart failure cardiologist demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

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Preserved Ejection Fraction Heart Failure 110

Frontiers in Cardiovascular Medicine

FEBRUARY 24, 2025

The increasing prevalence of heart failure (HF) has led to advancements in therapeutic strategies, including the development of new pharmacological treatments and the expansion of guideline recommendations across the spectrum of left ventricular ejection fractions.

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Heart Failure Heart Transplant Pharmacology Transplant 52

Medical Xpress - Cardiology

JANUARY 24, 2025

A specially designed drug prevented laboratory mice from developing heart failure after heart attacks, according to new research from Cedars-Sinai. This discovery could lead to new treatments to prevent heart failure, a serious cardiac condition that develops in up to 30% of heart attack survivors within one year.

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Heart attacks Heart Attack Heart Failure Laboratory 111

Medical Xpress - Cardiology

JULY 29, 2024

A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

Preserved Ejection Fraction 111

Preserved Ejection Fraction Heart Failure Research Hospital 111

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

AimThe association between red cell distribution widthalbumin ratio (RAR) and the risk of all-cause mortality in intensive care unit (ICU) patients with heart failure remains uncertain. database was utilized for the analysis of ICU patients with heart failure.

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Heart Failure ICU Physiology Outcomes 52

Heart BMJ

JANUARY 29, 2025

Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes.

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Heart Failure Circulation Biomarkers Atrial Fibrillation 52

Science Daily - Heart Disease

SEPTEMBER 30, 2024

Scientists discovered that blocking the activity of the hormone glucagon could treat a common and challenging type of heart failure that affects millions worldwide.

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Heart Failure 109

Medical Xpress - Cardiology

AUGUST 19, 2024

Heart failure is a leading cause of death worldwide and is especially fatal for people who don't have access to medical facilities. So, a team of researchers aims to bring heart failure screening from the lab to the home.

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Heart Failure COVID-19 Biomarkers Research 106

Open Heart

FEBRUARY 27, 2025

Background Iron deficiency (ID) is a highly prevalent comorbidity in patients with chronic and acute heart failure and is associated with worse clinical outcomes. We aimed to evaluate the prevalence and clinical characteristics of ID and its association with in-hospital congestion and postdischarge outcomes.

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Heart Failure Hospital Outcomes 52

Science Daily - Heart Disease

NOVEMBER 20, 2024

Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with obesity and heart failure with preserved pump function, new research reveals.

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Heart Failure Obesity Diabetes Research 111