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Heart–brain interaction in cardiogenic dementia: pathophysiology and therapeutic potential

Frontiers in Cardiovascular Medicine

An increasing number of preclinical and clinical studies have confirmed a causal relationship between heart and brain diseases. Cardiogenic dementia is a cognitive impairment caused by heart dysfunction and has received increasing research attention.

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Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction

Cardiovascular Diabetology

Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.

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Association between caseload volume and outcomes in left ventricular assist device implantations – a EUROMACS analysis

European Journal of Heart Failure

Patients from higher volume centres more frequently presented in INTERMACS levels 1 and 2, suffered from right heart dysfunction and needed inotropic support. Cumulative follow-up was 10003 patient-years, with a median follow-up of 1.54years (interquartile range 0.523.15). No difference was observed in adjusted 1-year survival.

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New 4D imaging may detect poor pumping in deadly heart disease

Medical Xpress - Cardiology

In a new study published in iScience, Mayo Clinic researchers found that a novel 4D echo imaging method that measures cardiac strain may detect subtle changes in the heart's dysfunction during acute myocarditis, a deadly heart disease.

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SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

However, researchers said the drug may be helpful in reducing heart failure risks, including hospitalization, following a heart attack. Researchers tracked outcomes for a median of just under 18 months. SGLT-2 inhibitors were initially approved to treat Type 2 diabetes by lowering blood sugar.

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Aria CV Announces First Patient Successfully Implanted with Second-Generation Pulmonary Hypertension System

DAIC

Vincent Cardiovascular Research Institute in Indianapolis, Indiana. The Aria CV Pulmonary Hypertension System is an implantable gas-filled balloon that is introduced percutaneously and functions in the main pulmonary artery to alleviate the excessive workload on the right heart that results in right heart failure.

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EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

While composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce heart failure risks after a heart attack, according to results from the EMPACT-MI trial presented on day one of the American College of Cardiology Scientific Sessions, ACC.24, 24, being held in Atlanta, GA.