DAIC

JULY 11, 2024

Heart failure (HF) is a growing worldwide public health issue affecting 64 million people annually 1 and is associated with high mortality, lower quality of life and reduced physical capacity while placing substantial costs on the healthcare system.

Heart Dysfunction 109

Heart Dysfunction Quality of Life Heart Failure Public Health 109

Science Daily - Heart Disease

JANUARY 30, 2025

Heart failure with preserved ejection function is a lethal form of heart failure, with few effective treatments. A team has now identified an enzyme, alpha-kinase 2 (ALPK2), that is specifically expressed in the heart and regulates the heart dysfunction that leads to heart failure with preserved ejection function.

Heart Failure 64

Heart Failure Heart Dysfunction 64

Circulation: Heart Failure

FEBRUARY 25, 2025

Circulation: Heart Failure, Ahead of Print. SERCA2a (sarco/endoplasmic reticulum Ca2+ATPase type 2a), which plays a crucial role in controlling intracellular Ca2+signaling and myocardial cell function, is downregulated and inactivated during sepsis-induced heart dysfunction.

Heart Dysfunction 40

Heart Dysfunction Heart Failure Circulation 40

Cardiovascular Diabetology

NOVEMBER 4, 2024

Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.

Preserved Ejection Fraction 52

Preserved Ejection Fraction Cardiac Function Heart Dysfunction Heart Failure 52

Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

An increasing number of preclinical and clinical studies have confirmed a causal relationship between heart and brain diseases. Cardiogenic dementia is a cognitive impairment caused by heart dysfunction and has received increasing research attention.

Dementia 64

Dementia Coronary Artery Disease Quality of Life Myocardial Infarction 64

Dr. S. Venkatesan MD

AUGUST 3, 2024

Gorter TM, van Veldhuisen DJ, Bauersachs et al Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail.

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Pulmonary Heart Dysfunction 52

Circulation

NOVEMBER 11, 2024

Heart transplantation remains a vital treatment for end-stage heart failure, yet the scarcity of suitable donor hearts makes the treatment unavailable to many patients in critical need. Circulation, Volume 150, Issue Suppl_1 , Page A4146828-A4146828, November 12, 2024.

Transplant 40

Transplant Heart Transplant Heart Dysfunction Heart Failure 40