HeartSciences Announces Allowance of U.S Patent for AI-ECG Assessment of Left Ventricular and Right Ventricular Heart Dysfunction
DAIC
JULY 11, 2024
mtaschetta-millane Thu, 07/11/2024 - 10:53 July 11, 2024 — Heart Test Laboratories, Inc.
Heart Dysfunction Related Topics 
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Succinylation of SERCA2a at K352 Promotes Its Ubiquitinoylation and Degradation by Proteasomes in Sepsis-Induced Heart Dysfunction
Circulation: Heart Failure
FEBRUARY 25, 2025
SERCA2a (sarco/endoplasmic reticulum Ca2+ATPase type 2a), which plays a crucial role in controlling intracellular Ca2+signaling and myocardial cell function, is downregulated and inactivated during sepsis-induced heart dysfunction. However, the cause of this dysregulation remains unclear.
A new therapeutic target for a lethal form of heart failure: ALPK2
Science Daily - Heart Disease
JANUARY 30, 2025
Heart failure with preserved ejection function is a lethal form of heart failure, with few effective treatments. A team has now identified an enzyme, alpha-kinase 2 (ALPK2), that is specifically expressed in the heart and regulates the heart dysfunction that leads to heart failure with preserved ejection function.
Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction
Cardiovascular Diabetology
NOVEMBER 4, 2024
Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.
Artificial intelligence-enabled phenotyping of patients with severe aortic stenosis: on the recovery of extra-aortic valve cardiac damage after transcatheter aortic valve replacement
Open Heart
OCTOBER 19, 2022
However, right heart dysfunction as well as the proportion of patients with severe tricuspid regurgitation remained unchanged. Clusters with persistent right heart dysfunction ultimately displayed 2-year survival rates of 69.2% (95% CI 56.6% ±15.8 ±15.1 mm Hg, p value: 0.0079). to 84.7%) and 74.6% (95% CI 65.9%
Heart–brain interaction in cardiogenic dementia: pathophysiology and therapeutic potential
Frontiers in Cardiovascular Medicine
JANUARY 23, 2024
An increasing number of preclinical and clinical studies have confirmed a causal relationship between heart and brain diseases. Cardiogenic dementia is a cognitive impairment caused by heart dysfunction and has received increasing research attention.
A case report of successful rescue using veno-arterial extracorporeal membrane oxygenation: managing cerebral-cardiac syndrome
Frontiers in Cardiovascular Medicine
APRIL 11, 2024
IntroductionThe presence of cerebral-cardiac syndrome, wherein brain diseases coincide with heart dysfunction, significantly impacts patient prognosis. In severe instances, circulatory failure may ensue, posing a life-threatening scenario necessitating immediate life support measures, particularly effective circulatory support methods.
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