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HeartSciences Announces Allowance of U.S Patent for AI-ECG Assessment of Left Ventricular and Right Ventricular Heart Dysfunction

DAIC

mtaschetta-millane Thu, 07/11/2024 - 10:53 July 11, 2024 — Heart Test Laboratories, Inc.

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Succinylation of SERCA2a at K352 Promotes Its Ubiquitinoylation and Degradation by Proteasomes in Sepsis-Induced Heart Dysfunction

Circulation: Heart Failure

SERCA2a (sarco/endoplasmic reticulum Ca2+ATPase type 2a), which plays a crucial role in controlling intracellular Ca2+signaling and myocardial cell function, is downregulated and inactivated during sepsis-induced heart dysfunction. However, the cause of this dysregulation remains unclear.

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New 4D imaging may detect poor pumping in deadly heart disease

Medical Xpress - Cardiology

In a new study published in iScience, Mayo Clinic researchers found that a novel 4D echo imaging method that measures cardiac strain may detect subtle changes in the heart's dysfunction during acute myocarditis, a deadly heart disease.

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A new therapeutic target for a lethal form of heart failure: ALPK2

Science Daily - Heart Disease

Heart failure with preserved ejection function is a lethal form of heart failure, with few effective treatments. A team has now identified an enzyme, alpha-kinase 2 (ALPK2), that is specifically expressed in the heart and regulates the heart dysfunction that leads to heart failure with preserved ejection function.

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Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction

Cardiovascular Diabetology

Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.

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Aria CV Announces First Patient Successfully Implanted with Second-Generation Pulmonary Hypertension System

DAIC

We are proud to have performed the first implant of this novel device, as it offers an alternative treatment for patients who remain significantly impacted by right heart dysfunction related to pulmonary hypertension, which has limited approved therapy options,” said Dr. Ashwin Ravichandran of Ascension St.

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Artificial intelligence-enabled phenotyping of patients with severe aortic stenosis: on the recovery of extra-aortic valve cardiac damage after transcatheter aortic valve replacement

Open Heart

However, right heart dysfunction as well as the proportion of patients with severe tricuspid regurgitation remained unchanged. Clusters with persistent right heart dysfunction ultimately displayed 2-year survival rates of 69.2% (95% CI 56.6% ±15.8 ±15.1 mm Hg, p value: 0.0079). to 84.7%) and 74.6% (95% CI 65.9%